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Trial details imported from

For full trial details, please see the original record at

Registration number
Ethics application status
Date submitted
Date registered
Date last updated

Titles & IDs
Public title
A Targeted Strengthening Program Following Total Hip Replacement.
Scientific title
A Targeted Strengthening Program Following Total Hip Replacement.
Secondary ID [1] 0 0
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Total Hip Joint Replacement 0 0
Condition category
Condition code

Study type
Description of intervention(s) / exposure
Behaviour - Strength training program

Behaviour: Strength training program

Intervention code [1] 0 0
Comparator / control treatment
Control group

Primary outcome [1] 0 0
Lower limb strength using a step test
Timepoint [1] 0 0
Secondary outcome [1] 0 0
Pain, stiffness and function using the WOMAC questionnaire.
Timepoint [1] 0 0
Secondary outcome [2] 0 0
Function using the Timed Up-and-Go Test.
Timepoint [2] 0 0
Secondary outcome [3] 0 0
Quality of life using the AQoL
Timepoint [3] 0 0
Secondary outcome [4] 0 0
Spatiotemporal measures of walking using an instrumented mat.
Timepoint [4] 0 0
Secondary outcome [5] 0 0
Hip joint torques using 3-D motion analysis.
Timepoint [5] 0 0

Key inclusion criteria
- primary uncomplicated total hip joint replacement 6-8 weeks prior to enrolment.

- able to walk 45m independently with or without walking aid.

- able to comprehend instructions

- prior joint replacement on the other side at least 12 months previously
Minimum age
No limit
Maximum age
No limit
Both males and females
Can healthy volunteers participate?
Key exclusion criteria
- unable to fully weight-bear on affected limb

- pre-existing neurological or orthopaedic condition affecting gait

- revision surgery

- post-operative complications, e.g. wound infection

- uncontrolled systemic disease

Study design
Purpose of the study
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Masking / blinding
Blinded (masking used)
Who is / are masked / blinded?

Intervention assignment
Other design features
Not Applicable
Type of endpoint(s)
Statistical methods / analysis

Recruitment status
Data analysis
Reason for early stopping/withdrawal
Other reasons
Date of first participant enrolment
Date of last participant enrolment
Date of last data collection
Sample size
Accrual to date
Recruitment in Australia
Recruitment state(s)
Recruitment hospital [1] 0 0
Austin Health - Melbourne
Recruitment postcode(s) [1] 0 0
3084 - Melbourne

Funding & Sponsors
Primary sponsor type
University of Melbourne

Ethics approval
Ethics application status

Brief summary
Total Hip Replacement (THR) is a common surgical procedure performed in people with hip
osteoarthritis and appears to be effective in relieving pain and improving function. However
significant wasting and weakness of the hip and knee muscles persists post-operatively.
Although relief of pain and improvement of function are important outcomes following THR,
weakness of the hip and knee muscles reduces a person's ability to manage stairs, slopes,
public transport and results in persistent gait abnormalities. Since lower limb weakness is
one of the risk factors for falls, it is important that patients undergo a strengthening
program post-operatively. The hypothesis is that lower limb strength and function will be
better in patients who undergo a strengthening program post-operatively than in those who
have usual care.
Trial website
Trial related presentations / publications
Public notes

Principal investigator
Name 0 0
Mary P Galea, PhD
Address 0 0
University of Melbourne
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for public queries
Name 0 0
Address 0 0
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for scientific queries

Summary results
Other publications