We are experiencing 4 week turn-around time in review of submissions and resubmissions. We recommend commencing this process concurrently with your ethics submission and allowing at least 8 weeks for registration to be completed from date of first submission. We currently do not have the capacity to expedite reviews.

Note also there are delays to review of updates. We appreciate your patience.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been endorsed by the ANZCTR. Before participating in a study, talk to your health care provider and refer to this information for consumers
Trial details imported from ClinicalTrials.gov

For full trial details, please see the original record at https://clinicaltrials.gov/show/NCT02680574




Registration number
NCT02680574
Ethics application status
Date submitted
9/02/2016
Date registered
11/02/2016
Date last updated
16/09/2020

Titles & IDs
Public title
Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)
Scientific title
Phase 3, Randomized, Open-label, Active-controlled Study Evaluating the Efficacy and Safety of Oral Vadadustat for the Maintenance Treatment of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD) (PRO2TECT-CONVERSION)
Secondary ID [1] 0 0
2015-004774-14
Secondary ID [2] 0 0
AKB-6548-CI-0015
Universal Trial Number (UTN)
Trial acronym
PRO2TECT
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Anemia 0 0
Non-dialysis-dependent Chronic Kidney Disease 0 0
Condition category
Condition code
Renal and Urogenital 0 0 0 0
Kidney disease
Renal and Urogenital 0 0 0 0
Other renal and urogenital disorders
Blood 0 0 0 0
Anaemia

Intervention/exposure
Study type
Interventional
Description of intervention(s) / exposure
Treatment: Drugs - vadadustat
Treatment: Drugs - darbepoetin alfa

Experimental: vadadustat -

Active Comparator: darbepoetin alfa -


Treatment: Drugs: vadadustat
oral tablet

Treatment: Drugs: darbepoetin alfa
Subcutaneous

Intervention code [1] 0 0
Treatment: Drugs
Comparator / control treatment
Control group

Outcomes
Primary outcome [1] 0 0
Mean change in Hb between baseline and the primary evaluation period
Timepoint [1] 0 0
Baseline visit, Week 36
Primary outcome [2] 0 0
Major adverse cardiovascular events (MACE), defined as all-cause mortality, non-fatal myocardial infarction, or non-fatal stroke
Timepoint [2] 0 0
From Baseline visit to end of study (event-driven, minimum 1 year)
Secondary outcome [1] 0 0
Mean change in Hb value between Baseline and the secondary evaluation period
Timepoint [1] 0 0
Baseline visit, Week 52
Secondary outcome [2] 0 0
Proportion of subjects with Hb values within the target range during the primary evaluation period
Timepoint [2] 0 0
Baseline visit, Week 36
Secondary outcome [3] 0 0
Adverse Events (AEs) and Serious Adverse Events (SAEs)
Timepoint [3] 0 0
From Baseline visit to end of study (event-driven, minimum 1 year)
Secondary outcome [4] 0 0
Proportion of time with Hb values within the target range during the primary evaluation period
Timepoint [4] 0 0
Baseline visit, Week 36
Secondary outcome [5] 0 0
Proportion of time with Hb values within the target range during the secondary evaluation period
Timepoint [5] 0 0
Baseline visit, Week 52
Secondary outcome [6] 0 0
Proportion of subjects with Hb values within the target range during the secondary evaluation period
Timepoint [6] 0 0
Baseline visit, Week 52
Secondary outcome [7] 0 0
Proportion of subjects with Hb increase of >1.0 g/dL from Baseline visit
Timepoint [7] 0 0
From baseline visit to end of study (event-driven, minimum 36 weeks)
Secondary outcome [8] 0 0
Time to achieve Hb increase of 1.0 g/dL from Baseline visit
Timepoint [8] 0 0
From baseline visit to end of study (event-driven, minimum 36 weeks)
Secondary outcome [9] 0 0
Mean change in Hb between Baseline (mean pretreatment Hb) and the primary evaluation period (mean Hgb from weeks 24-36) stratified b pre-baseline ESA exposure
Timepoint [9] 0 0
Baseline visit, Week 36
Secondary outcome [10] 0 0
Proportion of subjects receiving IV iron therapy
Timepoint [10] 0 0
Baseline visit, Week 52
Secondary outcome [11] 0 0
Mean monthly dose of IV elemental iron administered in subjects who have received IV iron
Timepoint [11] 0 0
Baseline visit, Week 52
Secondary outcome [12] 0 0
Proportion of subjects receiving RBC transfusion(s)
Timepoint [12] 0 0
Baseline visit, Week 52

Eligibility
Key inclusion criteria
- =18 years of age

- Diagnosis of CKD with an eGFR =60 mL/min/1.73 m^2 at Screening and not expected to
start dialysis within 6 months of Screening

- Currently maintained on ESA therapy, with a dose received within 6 weeks prior to or
during Screening

- Mean Screening HGB between 8.0 and 11.0 g/dL (inclusive) in the US and between 9.0 and
12.0 g/dL (inclusive) outside of the US
Minimum age
18 Years
Maximum age
No limit
Gender
Both males and females
Can healthy volunteers participate?
No
Key exclusion criteria
- Uncontrolled hypertension

- Severe heart failure at Screening (New York Heart Association Class IV)

- Acute coronary syndrome (hospitalization for unstable angina or myocardial
infarction), surgical or percutaneous intervention for coronary, cerebrovascular, or
peripheral artery disease (aortic or lower extremity), surgical or percutaneous
valvular replacement or repair, sustained ventricular tachycardia, hospitalization for
HF, or stroke within 12 weeks prior to or during Screening

- Hypersensitivity to darbepoetin or vadadustat or to any of their excipients

Study design
Purpose of the study
Treatment
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Masking / blinding
Open (masking not used)
Who is / are masked / blinded?



Intervention assignment
Parallel
Other design features
Phase
Phase 3
Type of endpoint(s)
Statistical methods / analysis

Recruitment
Recruitment status
Completed
Data analysis
Reason for early stopping/withdrawal
Other reasons
Date of first participant enrolment
Anticipated
Actual
Date of last participant enrolment
Anticipated
Actual
Date of last data collection
Anticipated
Actual
Sample size
Target
Accrual to date
Final
Recruitment in Australia
Recruitment state(s)
NSW,QLD,SA,TAS,VIC,WA
Recruitment hospital [1] 0 0
Research Site - Camperdown
Recruitment hospital [2] 0 0
Research Site - Liverpool
Recruitment hospital [3] 0 0
Research Site - Westmead
Recruitment hospital [4] 0 0
Research Site - Cairns
Recruitment hospital [5] 0 0
Research Site - Gold Coast
Recruitment hospital [6] 0 0
Research Site - Adelaide
Recruitment hospital [7] 0 0
Research Site - Launceston
Recruitment hospital [8] 0 0
Research Site - Bentleigh East
Recruitment hospital [9] 0 0
Research Site - Box Hill
Recruitment hospital [10] 0 0
Research Site - Fitzroy
Recruitment hospital [11] 0 0
Research Site - Nedlands
Recruitment hospital [12] 0 0
Research Site - Perth
Recruitment postcode(s) [1] 0 0
2050 - Camperdown
Recruitment postcode(s) [2] 0 0
2170 - Liverpool
Recruitment postcode(s) [3] 0 0
2145 - Westmead
Recruitment postcode(s) [4] 0 0
4870 - Cairns
Recruitment postcode(s) [5] 0 0
9726 - Gold Coast
Recruitment postcode(s) [6] 0 0
5000 - Adelaide
Recruitment postcode(s) [7] 0 0
7250 - Launceston
Recruitment postcode(s) [8] 0 0
3165 - Bentleigh East
Recruitment postcode(s) [9] 0 0
3128 - Box Hill
Recruitment postcode(s) [10] 0 0
3065 - Fitzroy
Recruitment postcode(s) [11] 0 0
6009 - Nedlands
Recruitment postcode(s) [12] 0 0
6000 - Perth
Recruitment outside Australia
Country [1] 0 0
United States of America
State/province [1] 0 0
Alabama
Country [2] 0 0
United States of America
State/province [2] 0 0
Arizona
Country [3] 0 0
United States of America
State/province [3] 0 0
California
Country [4] 0 0
United States of America
State/province [4] 0 0
Colorado
Country [5] 0 0
United States of America
State/province [5] 0 0
Connecticut
Country [6] 0 0
United States of America
State/province [6] 0 0
Florida
Country [7] 0 0
United States of America
State/province [7] 0 0
Georgia
Country [8] 0 0
United States of America
State/province [8] 0 0
Idaho
Country [9] 0 0
United States of America
State/province [9] 0 0
Illinois
Country [10] 0 0
United States of America
State/province [10] 0 0
Indiana
Country [11] 0 0
United States of America
State/province [11] 0 0
Louisiana
Country [12] 0 0
United States of America
State/province [12] 0 0
Maine
Country [13] 0 0
United States of America
State/province [13] 0 0
Maryland
Country [14] 0 0
United States of America
State/province [14] 0 0
Massachusetts
Country [15] 0 0
United States of America
State/province [15] 0 0
Michigan
Country [16] 0 0
United States of America
State/province [16] 0 0
Minnesota
Country [17] 0 0
United States of America
State/province [17] 0 0
Mississippi
Country [18] 0 0
United States of America
State/province [18] 0 0
Missouri
Country [19] 0 0
United States of America
State/province [19] 0 0
Montana
Country [20] 0 0
United States of America
State/province [20] 0 0
Nebraska
Country [21] 0 0
United States of America
State/province [21] 0 0
Nevada
Country [22] 0 0
United States of America
State/province [22] 0 0
New Hampshire
Country [23] 0 0
United States of America
State/province [23] 0 0
New Jersey
Country [24] 0 0
United States of America
State/province [24] 0 0
New Mexico
Country [25] 0 0
United States of America
State/province [25] 0 0
New York
Country [26] 0 0
United States of America
State/province [26] 0 0
North Carolina
Country [27] 0 0
United States of America
State/province [27] 0 0
Ohio
Country [28] 0 0
United States of America
State/province [28] 0 0
Oregon
Country [29] 0 0
United States of America
State/province [29] 0 0
Pennsylvania
Country [30] 0 0
United States of America
State/province [30] 0 0
Rhode Island
Country [31] 0 0
United States of America
State/province [31] 0 0
South Carolina
Country [32] 0 0
United States of America
State/province [32] 0 0
Tennessee
Country [33] 0 0
United States of America
State/province [33] 0 0
Texas
Country [34] 0 0
United States of America
State/province [34] 0 0
Utah
Country [35] 0 0
United States of America
State/province [35] 0 0
Vermont
Country [36] 0 0
United States of America
State/province [36] 0 0
Virginia
Country [37] 0 0
United States of America
State/province [37] 0 0
Washington
Country [38] 0 0
United States of America
State/province [38] 0 0
Wisconsin
Country [39] 0 0
Argentina
State/province [39] 0 0
Buenos Aires
Country [40] 0 0
Argentina
State/province [40] 0 0
Mendoza
Country [41] 0 0
Argentina
State/province [41] 0 0
Santa Fe
Country [42] 0 0
Argentina
State/province [42] 0 0
Tucuman
Country [43] 0 0
Argentina
State/province [43] 0 0
Ciudad Autonoma Buenos Aires
Country [44] 0 0
Argentina
State/province [44] 0 0
Cordoba
Country [45] 0 0
Argentina
State/province [45] 0 0
Corrientes
Country [46] 0 0
Argentina
State/province [46] 0 0
Salta
Country [47] 0 0
Argentina
State/province [47] 0 0
San Luis
Country [48] 0 0
Austria
State/province [48] 0 0
St. Pölten
Country [49] 0 0
Austria
State/province [49] 0 0
Wien
Country [50] 0 0
Brazil
State/province [50] 0 0
Bahia
Country [51] 0 0
Brazil
State/province [51] 0 0
Ceará
Country [52] 0 0
Brazil
State/province [52] 0 0
Espírito Santo
Country [53] 0 0
Brazil
State/province [53] 0 0
Minas Gerais
Country [54] 0 0
Brazil
State/province [54] 0 0
Paraná
Country [55] 0 0
Brazil
State/province [55] 0 0
Rio Do Janeiro
Country [56] 0 0
Brazil
State/province [56] 0 0
Rio Grande Do Sul
Country [57] 0 0
Brazil
State/province [57] 0 0
Santa Catarina
Country [58] 0 0
Brazil
State/province [58] 0 0
Sao Paulo
Country [59] 0 0
Bulgaria
State/province [59] 0 0
Byala
Country [60] 0 0
Bulgaria
State/province [60] 0 0
Cherven bryag
Country [61] 0 0
Bulgaria
State/province [61] 0 0
Lom
Country [62] 0 0
Bulgaria
State/province [62] 0 0
Silistra
Country [63] 0 0
Bulgaria
State/province [63] 0 0
Sliven
Country [64] 0 0
Bulgaria
State/province [64] 0 0
Smolyan
Country [65] 0 0
Bulgaria
State/province [65] 0 0
Sofia
Country [66] 0 0
Bulgaria
State/province [66] 0 0
Stara Zagora
Country [67] 0 0
Bulgaria
State/province [67] 0 0
Varna
Country [68] 0 0
Bulgaria
State/province [68] 0 0
Veliko Tarnovo
Country [69] 0 0
Bulgaria
State/province [69] 0 0
Vratsa
Country [70] 0 0
Canada
State/province [70] 0 0
Ontario
Country [71] 0 0
Chile
State/province [71] 0 0
Concepción
Country [72] 0 0
Chile
State/province [72] 0 0
Puerto Varas
Country [73] 0 0
Chile
State/province [73] 0 0
Santiago
Country [74] 0 0
Chile
State/province [74] 0 0
Temuco
Country [75] 0 0
Colombia
State/province [75] 0 0
Barranquilla
Country [76] 0 0
Colombia
State/province [76] 0 0
Bogota
Country [77] 0 0
Colombia
State/province [77] 0 0
Espinal
Country [78] 0 0
Colombia
State/province [78] 0 0
Manizales
Country [79] 0 0
Colombia
State/province [79] 0 0
Medellin
Country [80] 0 0
Colombia
State/province [80] 0 0
Medellín
Country [81] 0 0
Czechia
State/province [81] 0 0
Ceske Budejovice
Country [82] 0 0
Czechia
State/province [82] 0 0
Hradec Kralove
Country [83] 0 0
Czechia
State/province [83] 0 0
Praha 2
Country [84] 0 0
Czechia
State/province [84] 0 0
Praha 4
Country [85] 0 0
France
State/province [85] 0 0
Alpes De Haute Provence
Country [86] 0 0
France
State/province [86] 0 0
Loire
Country [87] 0 0
France
State/province [87] 0 0
Marne
Country [88] 0 0
France
State/province [88] 0 0
Val d'Oise
Country [89] 0 0
France
State/province [89] 0 0
Val De Marne
Country [90] 0 0
France
State/province [90] 0 0
Paris
Country [91] 0 0
Germany
State/province [91] 0 0
Baden Wuerttemberg
Country [92] 0 0
Germany
State/province [92] 0 0
Mecklenburg Vorpommern
Country [93] 0 0
Germany
State/province [93] 0 0
Nordrhein Westfalen
Country [94] 0 0
Germany
State/province [94] 0 0
Berlin
Country [95] 0 0
Germany
State/province [95] 0 0
Hamburg
Country [96] 0 0
Hungary
State/province [96] 0 0
Baja
Country [97] 0 0
Hungary
State/province [97] 0 0
Balatonfured
Country [98] 0 0
Hungary
State/province [98] 0 0
Budapest
Country [99] 0 0
Hungary
State/province [99] 0 0
Debrecen
Country [100] 0 0
Hungary
State/province [100] 0 0
Esztergom
Country [101] 0 0
Hungary
State/province [101] 0 0
Hodmezovasarhely
Country [102] 0 0
Hungary
State/province [102] 0 0
Kalocsa
Country [103] 0 0
Hungary
State/province [103] 0 0
Kaposvar
Country [104] 0 0
Hungary
State/province [104] 0 0
Kecskemet
Country [105] 0 0
Hungary
State/province [105] 0 0
Kistarcsa
Country [106] 0 0
Hungary
State/province [106] 0 0
Pecs
Country [107] 0 0
Hungary
State/province [107] 0 0
Szeged
Country [108] 0 0
Hungary
State/province [108] 0 0
Szigetvar
Country [109] 0 0
Israel
State/province [109] 0 0
Ashkelon
Country [110] 0 0
Israel
State/province [110] 0 0
Haifa
Country [111] 0 0
Israel
State/province [111] 0 0
Nahariya
Country [112] 0 0
Israel
State/province [112] 0 0
Ramat Gan
Country [113] 0 0
Israel
State/province [113] 0 0
Rishon Lezion
Country [114] 0 0
Italy
State/province [114] 0 0
Caserta
Country [115] 0 0
Italy
State/province [115] 0 0
Foggia
Country [116] 0 0
Italy
State/province [116] 0 0
Bari
Country [117] 0 0
Italy
State/province [117] 0 0
Lecco
Country [118] 0 0
Italy
State/province [118] 0 0
Milano
Country [119] 0 0
Italy
State/province [119] 0 0
Napoli
Country [120] 0 0
Italy
State/province [120] 0 0
Parma
Country [121] 0 0
Italy
State/province [121] 0 0
Pavia
Country [122] 0 0
Italy
State/province [122] 0 0
Roma
Country [123] 0 0
Italy
State/province [123] 0 0
Siena
Country [124] 0 0
Korea, Republic of
State/province [124] 0 0
Gyeonggi-do
Country [125] 0 0
Korea, Republic of
State/province [125] 0 0
Busan
Country [126] 0 0
Korea, Republic of
State/province [126] 0 0
Daegu
Country [127] 0 0
Korea, Republic of
State/province [127] 0 0
Seoul
Country [128] 0 0
Malaysia
State/province [128] 0 0
Kedah
Country [129] 0 0
Malaysia
State/province [129] 0 0
Kuala Lumpur
Country [130] 0 0
Malaysia
State/province [130] 0 0
Pulau Pinang
Country [131] 0 0
Mexico
State/province [131] 0 0
Coahuila
Country [132] 0 0
Mexico
State/province [132] 0 0
Distrito Federal
Country [133] 0 0
Mexico
State/province [133] 0 0
Guerrero
Country [134] 0 0
Mexico
State/province [134] 0 0
Hidalgo
Country [135] 0 0
Mexico
State/province [135] 0 0
Jalisco
Country [136] 0 0
Mexico
State/province [136] 0 0
Michoacán
Country [137] 0 0
Mexico
State/province [137] 0 0
Nuevo León
Country [138] 0 0
Mexico
State/province [138] 0 0
Queretaro
Country [139] 0 0
Mexico
State/province [139] 0 0
Sinaloa
Country [140] 0 0
Mexico
State/province [140] 0 0
Chihuahua
Country [141] 0 0
Mexico
State/province [141] 0 0
Durango
Country [142] 0 0
Mexico
State/province [142] 0 0
Veracruz
Country [143] 0 0
New Zealand
State/province [143] 0 0
Hamilton
Country [144] 0 0
New Zealand
State/province [144] 0 0
New Plymouth
Country [145] 0 0
Poland
State/province [145] 0 0
Nowa Sol
Country [146] 0 0
Puerto Rico
State/province [146] 0 0
Caguas
Country [147] 0 0
Romania
State/province [147] 0 0
Bucuresti
Country [148] 0 0
Romania
State/province [148] 0 0
Oradea
Country [149] 0 0
Romania
State/province [149] 0 0
Timisoara
Country [150] 0 0
Russian Federation
State/province [150] 0 0
Kazan
Country [151] 0 0
Russian Federation
State/province [151] 0 0
Kemerovo
Country [152] 0 0
Russian Federation
State/province [152] 0 0
Krasnoyarsk
Country [153] 0 0
Russian Federation
State/province [153] 0 0
Nizhniy Novgorod
Country [154] 0 0
Russian Federation
State/province [154] 0 0
Novosibirsk
Country [155] 0 0
Russian Federation
State/province [155] 0 0
Petrozavodsk
Country [156] 0 0
Russian Federation
State/province [156] 0 0
Pushkin
Country [157] 0 0
Russian Federation
State/province [157] 0 0
Saint-Petersburg
Country [158] 0 0
Russian Federation
State/province [158] 0 0
Yaroslavl
Country [159] 0 0
Serbia
State/province [159] 0 0
Belgrade
Country [160] 0 0
Serbia
State/province [160] 0 0
Kragujevac
Country [161] 0 0
Serbia
State/province [161] 0 0
Lazarevac
Country [162] 0 0
Serbia
State/province [162] 0 0
Nis
Country [163] 0 0
Serbia
State/province [163] 0 0
Zajecar
Country [164] 0 0
Slovakia
State/province [164] 0 0
Bardejov
Country [165] 0 0
Slovakia
State/province [165] 0 0
Bratislava
Country [166] 0 0
Slovakia
State/province [166] 0 0
Galanta
Country [167] 0 0
Slovakia
State/province [167] 0 0
Svidnik
Country [168] 0 0
Slovakia
State/province [168] 0 0
Trstena
Country [169] 0 0
South Africa
State/province [169] 0 0
Free State
Country [170] 0 0
South Africa
State/province [170] 0 0
Gauteng
Country [171] 0 0
South Africa
State/province [171] 0 0
KwaZulu-Natal
Country [172] 0 0
South Africa
State/province [172] 0 0
Western Cape
Country [173] 0 0
Spain
State/province [173] 0 0
Alicante
Country [174] 0 0
Spain
State/province [174] 0 0
Baleares
Country [175] 0 0
Spain
State/province [175] 0 0
Barcelona
Country [176] 0 0
Spain
State/province [176] 0 0
Málaga
Country [177] 0 0
Spain
State/province [177] 0 0
Almeria
Country [178] 0 0
Spain
State/province [178] 0 0
Badajoz
Country [179] 0 0
Spain
State/province [179] 0 0
Madrid
Country [180] 0 0
Spain
State/province [180] 0 0
Pamplona
Country [181] 0 0
Spain
State/province [181] 0 0
Sevilla
Country [182] 0 0
Spain
State/province [182] 0 0
Valencia
Country [183] 0 0
Turkey
State/province [183] 0 0
Ankara
Country [184] 0 0
Turkey
State/province [184] 0 0
Erciyes
Country [185] 0 0
Turkey
State/province [185] 0 0
Istanbul
Country [186] 0 0
Turkey
State/province [186] 0 0
Kocaeli
Country [187] 0 0
Ukraine
State/province [187] 0 0
Dnipro
Country [188] 0 0
Ukraine
State/province [188] 0 0
Ivano-Frankivsk
Country [189] 0 0
Ukraine
State/province [189] 0 0
Kharkiv
Country [190] 0 0
Ukraine
State/province [190] 0 0
Kropyvnytskyi
Country [191] 0 0
Ukraine
State/province [191] 0 0
Kyiv
Country [192] 0 0
Ukraine
State/province [192] 0 0
Lutsk
Country [193] 0 0
Ukraine
State/province [193] 0 0
Lviv
Country [194] 0 0
Ukraine
State/province [194] 0 0
Mykolaiv
Country [195] 0 0
Ukraine
State/province [195] 0 0
Odesa
Country [196] 0 0
Ukraine
State/province [196] 0 0
Vinnytsia
Country [197] 0 0
Ukraine
State/province [197] 0 0
Zaporizhzhia
Country [198] 0 0
United Kingdom
State/province [198] 0 0
Devon
Country [199] 0 0
United Kingdom
State/province [199] 0 0
Greater London
Country [200] 0 0
United Kingdom
State/province [200] 0 0
Greater Manchester
Country [201] 0 0
United Kingdom
State/province [201] 0 0
Hertfordshire
Country [202] 0 0
United Kingdom
State/province [202] 0 0
Leicestershire
Country [203] 0 0
United Kingdom
State/province [203] 0 0
Norfolk
Country [204] 0 0
United Kingdom
State/province [204] 0 0
South Yorkshire
Country [205] 0 0
United Kingdom
State/province [205] 0 0
Swansea

Funding & Sponsors
Primary sponsor type
Commercial sector/Industry
Name
Akebia Therapeutics
Address
Country

Ethics approval
Ethics application status

Summary
Brief summary
A multicenter, randomized, open-label, active-controlled Phase 3 study for the maintenance
treatment of anemia in subjects with NDD-CKD
Trial website
https://clinicaltrials.gov/show/NCT02680574
Trial related presentations / publications
Public notes

Contacts
Principal investigator
Name 0 0
Akebia Therapeutics
Address 0 0
Sponsor GmbH
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for public queries
Name 0 0
Address 0 0
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for scientific queries

Summary results
Other publications