Please note the ANZCTR will be unattended from Friday 20 December 2024 for the holidays. The Registry will re-open on Tuesday 7 January 2025. Submissions and updates will not be processed during that time.

Registering a new trial?

To achieve prospective registration, we recommend submitting your trial for registration at the same time as ethics submission.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been endorsed by the ANZCTR. Before participating in a study, talk to your health care provider and refer to this information for consumers
Trial details imported from ClinicalTrials.gov

For full trial details, please see the original record at https://clinicaltrials.gov/study/NCT01663402




Registration number
NCT01663402
Ethics application status
Date submitted
8/08/2012
Date registered
13/08/2012
Date last updated
18/03/2019

Titles & IDs
Public title
ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab
Scientific title
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of Alirocumab (SAR236553/REGN727) on the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome
Secondary ID [1] 0 0
2011-005698-21
Secondary ID [2] 0 0
EFC11570
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Atherosclerotic Cardiovascular Disease 0 0
Condition category
Condition code
Cardiovascular 0 0 0 0
Coronary heart disease
Cardiovascular 0 0 0 0
Diseases of the vasculature and circulation including the lymphatic system

Intervention/exposure
Study type
Interventional
Description of intervention(s) / exposure
Treatment: Drugs - Alirocumab
Treatment: Drugs - Placebo
Treatment: Drugs - LMT

Placebo comparator: Placebo - Placebo (for alirocumab) subcutaneous (SC) injection every 2 weeks (Q2W) added to stable Lipid-Modifying Therapy (LMT) for up to 64 months.

Experimental: Alirocumab 75 mg Q2W/Up to 150 mg Q2W - Alirocumab 75 mg SC injection Q2W added to stable LMT for up to 64 months. Alirocumab dose up-titrated to 150 mg Q2W from Month 2 when Low-Density Lipoprotein Cholesterol (LDL-C) levels \>=50 mg/dL (1.29 mmol/L) at Month 1; or if up-titration was missed due to unavailability of LDL-C value, it was up-titrated at month 4 based on LDL-C value at Month 2. For participants receiving 150 mg Q2W, alirocumab dose was down-titrated in a blinded manner to 75 mg Q2W if two consecutive values of LDL-C were \<25 mg/dL (0.65 mmol/L). For participants receiving 75 mg Q2W, alirocumab dose was switched to placebo in a blinded manner if two consecutive values of LDL-C were \<15 mg/dL (0.39 mmol/L).


Treatment: Drugs: Alirocumab
Alirocumab administered as SC injection of 1 mL in the abdomen or thigh with a disposable auto-injector.

Treatment: Drugs: Placebo
Placebo matched to alirocumab administered as a SC injection of 1 mL in the abdomen or thigh with a disposable auto-injector.

Treatment: Drugs: LMT
Statins (atorvastatin or rosuvastatin) at stable maximal tolerated dose of statin with or without other LMT as clinically indicated.

Intervention code [1] 0 0
Treatment: Drugs
Comparator / control treatment
Control group

Outcomes
Primary outcome [1] 0 0
Time to First Occurrence of Major Adverse Cardiovascular Event (MACE); Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [1] 0 0
From randomization up to 64 months
Secondary outcome [1] 0 0
Time to First Occurrence of Any Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [1] 0 0
From randomization up to 64 months
Secondary outcome [2] 0 0
Time to First Occurrence of Any Major Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [2] 0 0
From randomization up to 64 months
Secondary outcome [3] 0 0
Time to First Occurrence of Any Cardiovascular Event; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [3] 0 0
From randomization up to 64 months
Secondary outcome [4] 0 0
Time to First Occurrence of All-Cause Mortality, Non-Fatal Myocardial Infarction, Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [4] 0 0
From randomization up to 64 months
Secondary outcome [5] 0 0
Time to Coronary Heart Disease Death; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [5] 0 0
From randomization up to 64 months
Secondary outcome [6] 0 0
Time to Cardiovascular Death; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [6] 0 0
From randomization up to 64 months
Secondary outcome [7] 0 0
Time to All-Cause Death; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [7] 0 0
From randomization up to 64 months
Secondary outcome [8] 0 0
Time to First Occurrence of Any Non-Fatal Myocardial Infarction; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [8] 0 0
From randomization up to 64 months
Secondary outcome [9] 0 0
Time to First Occurrence of Fatal or Any Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [9] 0 0
From randomization up to 64 months
Secondary outcome [10] 0 0
Time to First Occurrence of Any Unstable Angina Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [10] 0 0
From randomization up to 64 months
Secondary outcome [11] 0 0
Time to First Occurrence of Any Ischemia-Driven Coronary Revascularization Procedure; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [11] 0 0
From randomization up to 64 months
Secondary outcome [12] 0 0
Time to First Occurrence of Any Congestive Heart Failure (CHF) Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study
Timepoint [12] 0 0
From randomization up to 64 months

Eligibility
Key inclusion criteria
Inclusion criteria :

Recently (< 52 weeks) hospitalized for ACS.
Minimum age
40 Years
Maximum age
No limit
Sex
Both males and females
Can healthy volunteers participate?
No
Key exclusion criteria
Exclusion criteria:

* Age < 40 years.
* ACS event occurring more than 52 weeks prior to randomization visit.
* LDL-C likely to be <70 mg/dL (<1.81 mmo/L), and apolipoprotein B (ApoB) <80 mg/dL (<0.8 g/L), and non - high-density lipoprotein cholesterol (HDL-C) <100 mg/dL (<2.59 mmol/L) with evidence-based medical and dietary management of dyslipidemia.

The above information is not intended to contain all considerations relevant to a participant's potential participation in a clinical trial.

Study design
Purpose of the study
Prevention
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Masking / blinding
Blinded (masking used)
Who is / are masked / blinded?
The people receiving the treatment/s


The people analysing the results/data
Intervention assignment
Parallel
Other design features
Phase
Phase 3
Type of endpoint/s
Statistical methods / analysis

Recruitment
Recruitment status
Completed
Data analysis
Reason for early stopping/withdrawal
Other reasons
Date of first participant enrolment
Anticipated
Actual
Date of last participant enrolment
Anticipated
Actual
Date of last data collection
Anticipated
Actual
Sample size
Target
Accrual to date
Final
Recruitment in Australia
Recruitment state(s)
Recruitment hospital [1] 0 0
Investigational Site Number 036002 - Ashford
Recruitment hospital [2] 0 0
Investigational Site Number 036023 - Auchenflower
Recruitment hospital [3] 0 0
Investigational Site Number 036024 - Ballarat
Recruitment hospital [4] 0 0
Investigational Site Number 036020 - Bedford Park
Recruitment hospital [5] 0 0
Investigational Site Number 036015 - Bruce
Recruitment hospital [6] 0 0
Investigational Site Number 036026 - Cairns
Recruitment hospital [7] 0 0
Investigational Site Number 036005 - Chermside
Recruitment hospital [8] 0 0
Investigational Site Number 036008 - Chermside
Recruitment hospital [9] 0 0
Investigational Site Number 036011 - Coffs Harbour
Recruitment hospital [10] 0 0
Investigational Site Number 036003 - Concord
Recruitment hospital [11] 0 0
Investigational Site Number 036017 - Elizabeth Vale
Recruitment hospital [12] 0 0
Investigational Site Number 036006 - Fullarton
Recruitment hospital [13] 0 0
Investigational Site Number 036004 - Gosford
Recruitment hospital [14] 0 0
Investigational Site Number 036019 - Heidelberg West
Recruitment hospital [15] 0 0
Investigational Site Number 036027 - Hobart
Recruitment hospital [16] 0 0
Investigational Site Number 036009 - Kogarah
Recruitment hospital [17] 0 0
Investigational Site Number 036012 - Mildura
Recruitment hospital [18] 0 0
Investigational Site Number 036028 - Nambour
Recruitment hospital [19] 0 0
Investigational Site Number 036013 - New Lambton
Recruitment hospital [20] 0 0
Investigational Site Number 036010 - Perth
Recruitment hospital [21] 0 0
Investigational Site Number 036014 - Prahran
Recruitment hospital [22] 0 0
Investigational Site Number 036018 - Redcliffe
Recruitment hospital [23] 0 0
Investigational Site Number 036022 - Richmond
Recruitment hospital [24] 0 0
Investigational Site Number 036025 - Woodville South
Recruitment hospital [25] 0 0
Investigational Site Number 036021 - Woolloongabba
Recruitment postcode(s) [1] 0 0
5035 - Ashford
Recruitment postcode(s) [2] 0 0
4066 - Auchenflower
Recruitment postcode(s) [3] 0 0
3353 - Ballarat
Recruitment postcode(s) [4] 0 0
5042 - Bedford Park
Recruitment postcode(s) [5] 0 0
2617 - Bruce
Recruitment postcode(s) [6] 0 0
4870 - Cairns
Recruitment postcode(s) [7] 0 0
4032 - Chermside
Recruitment postcode(s) [8] 0 0
2450 - Coffs Harbour
Recruitment postcode(s) [9] 0 0
2137 - Concord
Recruitment postcode(s) [10] 0 0
5112 - Elizabeth Vale
Recruitment postcode(s) [11] 0 0
5063 - Fullarton
Recruitment postcode(s) [12] 0 0
2250 - Gosford
Recruitment postcode(s) [13] 0 0
3081 - Heidelberg West
Recruitment postcode(s) [14] 0 0
7001 - Hobart
Recruitment postcode(s) [15] 0 0
2217 - Kogarah
Recruitment postcode(s) [16] 0 0
3500 - Mildura
Recruitment postcode(s) [17] 0 0
4560 - Nambour
Recruitment postcode(s) [18] 0 0
2305 - New Lambton
Recruitment postcode(s) [19] 0 0
6000 - Perth
Recruitment postcode(s) [20] 0 0
3004 - Prahran
Recruitment postcode(s) [21] 0 0
4020 - Redcliffe
Recruitment postcode(s) [22] 0 0
3121 - Richmond
Recruitment postcode(s) [23] 0 0
5011 - Woodville South
Recruitment postcode(s) [24] 0 0
4102 - Woolloongabba
Recruitment outside Australia
Country [1] 0 0
United States of America
State/province [1] 0 0
Alabama
Country [2] 0 0
United States of America
State/province [2] 0 0
Arizona
Country [3] 0 0
United States of America
State/province [3] 0 0
California
Country [4] 0 0
United States of America
State/province [4] 0 0
Colorado
Country [5] 0 0
United States of America
State/province [5] 0 0
Connecticut
Country [6] 0 0
United States of America
State/province [6] 0 0
Florida
Country [7] 0 0
United States of America
State/province [7] 0 0
Georgia
Country [8] 0 0
United States of America
State/province [8] 0 0
Idaho
Country [9] 0 0
United States of America
State/province [9] 0 0
Illinois
Country [10] 0 0
United States of America
State/province [10] 0 0
Indiana
Country [11] 0 0
United States of America
State/province [11] 0 0
Iowa
Country [12] 0 0
United States of America
State/province [12] 0 0
Kansas
Country [13] 0 0
United States of America
State/province [13] 0 0
Kentucky
Country [14] 0 0
United States of America
State/province [14] 0 0
Louisiana
Country [15] 0 0
United States of America
State/province [15] 0 0
Maine
Country [16] 0 0
United States of America
State/province [16] 0 0
Maryland
Country [17] 0 0
United States of America
State/province [17] 0 0
Massachusetts
Country [18] 0 0
United States of America
State/province [18] 0 0
Michigan
Country [19] 0 0
United States of America
State/province [19] 0 0
Minnesota
Country [20] 0 0
United States of America
State/province [20] 0 0
Missouri
Country [21] 0 0
United States of America
State/province [21] 0 0
Montana
Country [22] 0 0
United States of America
State/province [22] 0 0
Nebraska
Country [23] 0 0
United States of America
State/province [23] 0 0
Nevada
Country [24] 0 0
United States of America
State/province [24] 0 0
New Hampshire
Country [25] 0 0
United States of America
State/province [25] 0 0
New Jersey
Country [26] 0 0
United States of America
State/province [26] 0 0
New York
Country [27] 0 0
United States of America
State/province [27] 0 0
North Carolina
Country [28] 0 0
United States of America
State/province [28] 0 0
North Dakota
Country [29] 0 0
United States of America
State/province [29] 0 0
Ohio
Country [30] 0 0
United States of America
State/province [30] 0 0
Oklahoma
Country [31] 0 0
United States of America
State/province [31] 0 0
Oregon
Country [32] 0 0
United States of America
State/province [32] 0 0
Pennsylvania
Country [33] 0 0
United States of America
State/province [33] 0 0
Rhode Island
Country [34] 0 0
United States of America
State/province [34] 0 0
South Carolina
Country [35] 0 0
United States of America
State/province [35] 0 0
South Dakota
Country [36] 0 0
United States of America
State/province [36] 0 0
Tennessee
Country [37] 0 0
United States of America
State/province [37] 0 0
Texas
Country [38] 0 0
United States of America
State/province [38] 0 0
Utah
Country [39] 0 0
United States of America
State/province [39] 0 0
Vermont
Country [40] 0 0
United States of America
State/province [40] 0 0
Virginia
Country [41] 0 0
United States of America
State/province [41] 0 0
Washington
Country [42] 0 0
United States of America
State/province [42] 0 0
Wisconsin
Country [43] 0 0
Argentina
State/province [43] 0 0
Adrogue
Country [44] 0 0
Argentina
State/province [44] 0 0
Bahia Blanca
Country [45] 0 0
Argentina
State/province [45] 0 0
Caba
Country [46] 0 0
Argentina
State/province [46] 0 0
Ciudad De Buenos Aires
Country [47] 0 0
Argentina
State/province [47] 0 0
Ciudadela
Country [48] 0 0
Argentina
State/province [48] 0 0
Cordoba
Country [49] 0 0
Argentina
State/province [49] 0 0
Coronel Suarez
Country [50] 0 0
Argentina
State/province [50] 0 0
Corrientes
Country [51] 0 0
Argentina
State/province [51] 0 0
Córdoba
Country [52] 0 0
Argentina
State/province [52] 0 0
Junin
Country [53] 0 0
Argentina
State/province [53] 0 0
La Plata
Country [54] 0 0
Argentina
State/province [54] 0 0
Mar Del Plata
Country [55] 0 0
Argentina
State/province [55] 0 0
Mendoza
Country [56] 0 0
Argentina
State/province [56] 0 0
Merlo
Country [57] 0 0
Argentina
State/province [57] 0 0
Moron
Country [58] 0 0
Argentina
State/province [58] 0 0
Olivos
Country [59] 0 0
Argentina
State/province [59] 0 0
Quilmes
Country [60] 0 0
Argentina
State/province [60] 0 0
Rafaela
Country [61] 0 0
Argentina
State/province [61] 0 0
Ramos Mejia
Country [62] 0 0
Argentina
State/province [62] 0 0
Resistencia
Country [63] 0 0
Argentina
State/province [63] 0 0
Rosario
Country [64] 0 0
Argentina
State/province [64] 0 0
Salta
Country [65] 0 0
Argentina
State/province [65] 0 0
San Isidro
Country [66] 0 0
Argentina
State/province [66] 0 0
San Martin
Country [67] 0 0
Argentina
State/province [67] 0 0
San Miguel De Tucuman
Country [68] 0 0
Argentina
State/province [68] 0 0
San Nicolas
Country [69] 0 0
Argentina
State/province [69] 0 0
Santa Fe
Country [70] 0 0
Argentina
State/province [70] 0 0
Santa Rosa
Country [71] 0 0
Argentina
State/province [71] 0 0
Santiago Del Estero
Country [72] 0 0
Argentina
State/province [72] 0 0
Venado Tuerto
Country [73] 0 0
Argentina
State/province [73] 0 0
Villa Maria
Country [74] 0 0
Argentina
State/province [74] 0 0
Zarate
Country [75] 0 0
Austria
State/province [75] 0 0
Feldkirch
Country [76] 0 0
Austria
State/province [76] 0 0
Graz
Country [77] 0 0
Austria
State/province [77] 0 0
Salzburg
Country [78] 0 0
Austria
State/province [78] 0 0
Wien
Country [79] 0 0
Belgium
State/province [79] 0 0
Aalst
Country [80] 0 0
Belgium
State/province [80] 0 0
Antwerpen
Country [81] 0 0
Belgium
State/province [81] 0 0
Bonheiden
Country [82] 0 0
Belgium
State/province [82] 0 0
Brasschaat
Country [83] 0 0
Belgium
State/province [83] 0 0
Brussels
Country [84] 0 0
Belgium
State/province [84] 0 0
Bruxelles
Country [85] 0 0
Belgium
State/province [85] 0 0
Edegem
Country [86] 0 0
Belgium
State/province [86] 0 0
Genk
Country [87] 0 0
Belgium
State/province [87] 0 0
Gent
Country [88] 0 0
Belgium
State/province [88] 0 0
La Louviere
Country [89] 0 0
Belgium
State/province [89] 0 0
Leuven
Country [90] 0 0
Belgium
State/province [90] 0 0
Liège
Country [91] 0 0
Belgium
State/province [91] 0 0
Mechelen
Country [92] 0 0
Belgium
State/province [92] 0 0
Mol
Country [93] 0 0
Belgium
State/province [93] 0 0
Ottignies
Country [94] 0 0
Belgium
State/province [94] 0 0
Overpelt
Country [95] 0 0
Belgium
State/province [95] 0 0
Roeselare
Country [96] 0 0
Belgium
State/province [96] 0 0
Tienen
Country [97] 0 0
Bosnia and Herzegovina
State/province [97] 0 0
Banja Luka
Country [98] 0 0
Bosnia and Herzegovina
State/province [98] 0 0
Bihac
Country [99] 0 0
Bosnia and Herzegovina
State/province [99] 0 0
Mostar
Country [100] 0 0
Bosnia and Herzegovina
State/province [100] 0 0
Sarajevo
Country [101] 0 0
Bosnia and Herzegovina
State/province [101] 0 0
Tuzla
Country [102] 0 0
Bosnia and Herzegovina
State/province [102] 0 0
Zenica
Country [103] 0 0
Brazil
State/province [103] 0 0
Aparecida De Goiania
Country [104] 0 0
Brazil
State/province [104] 0 0
Belem
Country [105] 0 0
Brazil
State/province [105] 0 0
Belo Horizonte
Country [106] 0 0
Brazil
State/province [106] 0 0
Blumenau
Country [107] 0 0
Brazil
State/province [107] 0 0
Brasilia
Country [108] 0 0
Brazil
State/province [108] 0 0
Campina Grande Do Sul
Country [109] 0 0
Brazil
State/province [109] 0 0
Campinas
Country [110] 0 0
Brazil
State/province [110] 0 0
Canoas
Country [111] 0 0
Brazil
State/province [111] 0 0
Curitiba
Country [112] 0 0
Brazil
State/province [112] 0 0
Fortaleza
Country [113] 0 0
Brazil
State/province [113] 0 0
Goiania
Country [114] 0 0
Brazil
State/province [114] 0 0
Passo Fundo
Country [115] 0 0
Brazil
State/province [115] 0 0
Pelotas
Country [116] 0 0
Brazil
State/province [116] 0 0
Porto Alegre
Country [117] 0 0
Brazil
State/province [117] 0 0
Riberao Preto
Country [118] 0 0
Brazil
State/province [118] 0 0
Rio De Janeiro
Country [119] 0 0
Brazil
State/province [119] 0 0
Salvador
Country [120] 0 0
Brazil
State/province [120] 0 0
Santo Andre
Country [121] 0 0
Brazil
State/province [121] 0 0
Sao Bernardo Do Campo
Country [122] 0 0
Brazil
State/province [122] 0 0
Sao Jose Do Rio Preto
Country [123] 0 0
Brazil
State/province [123] 0 0
Sao Paulo
Country [124] 0 0
Brazil
State/province [124] 0 0
Tatuí
Country [125] 0 0
Brazil
State/province [125] 0 0
Uberlandia
Country [126] 0 0
Bulgaria
State/province [126] 0 0
Blagoevgrad
Country [127] 0 0
Bulgaria
State/province [127] 0 0
Burgas
Country [128] 0 0
Bulgaria
State/province [128] 0 0
Pazardzhik
Country [129] 0 0
Bulgaria
State/province [129] 0 0
Pleven
Country [130] 0 0
Bulgaria
State/province [130] 0 0
Plovdiv
Country [131] 0 0
Bulgaria
State/province [131] 0 0
Sandanski
Country [132] 0 0
Bulgaria
State/province [132] 0 0
Smoljan
Country [133] 0 0
Bulgaria
State/province [133] 0 0
Sofia
Country [134] 0 0
Bulgaria
State/province [134] 0 0
Varna
Country [135] 0 0
Bulgaria
State/province [135] 0 0
Veliko Tarnovo
Country [136] 0 0
Canada
State/province [136] 0 0
Calgary
Country [137] 0 0
Canada
State/province [137] 0 0
Cambridge
Country [138] 0 0
Canada
State/province [138] 0 0
Edmonton
Country [139] 0 0
Canada
State/province [139] 0 0
Granby
Country [140] 0 0
Canada
State/province [140] 0 0
Halifax
Country [141] 0 0
Canada
State/province [141] 0 0
Hamilton
Country [142] 0 0
Canada
State/province [142] 0 0
Joliette
Country [143] 0 0
Canada
State/province [143] 0 0
Kitchener
Country [144] 0 0
Canada
State/province [144] 0 0
Levis
Country [145] 0 0
Canada
State/province [145] 0 0
Longueuil
Country [146] 0 0
Canada
State/province [146] 0 0
Moncton
Country [147] 0 0
Canada
State/province [147] 0 0
Montreal
Country [148] 0 0
Canada
State/province [148] 0 0
New Westminster
Country [149] 0 0
Canada
State/province [149] 0 0
Newmarket
Country [150] 0 0
Canada
State/province [150] 0 0
Oshawa
Country [151] 0 0
Canada
State/province [151] 0 0
Ottawa
Country [152] 0 0
Canada
State/province [152] 0 0
Penticton
Country [153] 0 0
Canada
State/province [153] 0 0
Red Deer
Country [154] 0 0
Canada
State/province [154] 0 0
Saint-Jerome
Country [155] 0 0
Canada
State/province [155] 0 0
Sainte-Foy
Country [156] 0 0
Canada
State/province [156] 0 0
Scarborough
Country [157] 0 0
Canada
State/province [157] 0 0
Sherbrooke
Country [158] 0 0
Canada
State/province [158] 0 0
St-Georges
Country [159] 0 0
Canada
State/province [159] 0 0
St. Catherines
Country [160] 0 0
Canada
State/province [160] 0 0
St. John'S
Country [161] 0 0
Canada
State/province [161] 0 0
St. John
Country [162] 0 0
Canada
State/province [162] 0 0
Surrey
Country [163] 0 0
Canada
State/province [163] 0 0
Sydney
Country [164] 0 0
Canada
State/province [164] 0 0
Thetford Mines
Country [165] 0 0
Canada
State/province [165] 0 0
Thunder Bay
Country [166] 0 0
Canada
State/province [166] 0 0
Toronto
Country [167] 0 0
Canada
State/province [167] 0 0
Trois-Rivieres
Country [168] 0 0
Canada
State/province [168] 0 0
Vancouver
Country [169] 0 0
Canada
State/province [169] 0 0
Victoria
Country [170] 0 0
Canada
State/province [170] 0 0
Winnipeg
Country [171] 0 0
Chile
State/province [171] 0 0
Concepcion
Country [172] 0 0
Chile
State/province [172] 0 0
Osorno
Country [173] 0 0
Chile
State/province [173] 0 0
Punta Arenas
Country [174] 0 0
Chile
State/province [174] 0 0
Santiago
Country [175] 0 0
Chile
State/province [175] 0 0
Talca
Country [176] 0 0
Chile
State/province [176] 0 0
Temuco
Country [177] 0 0
Chile
State/province [177] 0 0
Valdivia
Country [178] 0 0
Chile
State/province [178] 0 0
Viña Del Mar
Country [179] 0 0
China
State/province [179] 0 0
Baotou
Country [180] 0 0
China
State/province [180] 0 0
Beijing
Country [181] 0 0
China
State/province [181] 0 0
Changchun
Country [182] 0 0
China
State/province [182] 0 0
Changsha
Country [183] 0 0
China
State/province [183] 0 0
Chongqing
Country [184] 0 0
China
State/province [184] 0 0
Fuzhou
Country [185] 0 0
China
State/province [185] 0 0
Guangzhou
Country [186] 0 0
China
State/province [186] 0 0
Guiyang
Country [187] 0 0
China
State/province [187] 0 0
Hangzhou
Country [188] 0 0
China
State/province [188] 0 0
Hohhot
Country [189] 0 0
China
State/province [189] 0 0
Jinan
Country [190] 0 0
China
State/province [190] 0 0
Lanzhou
Country [191] 0 0
China
State/province [191] 0 0
Luzhou
Country [192] 0 0
China
State/province [192] 0 0
Nanchang
Country [193] 0 0
China
State/province [193] 0 0
Nanjing
Country [194] 0 0
China
State/province [194] 0 0
Shanghai
Country [195] 0 0
China
State/province [195] 0 0
Shenyang
Country [196] 0 0
China
State/province [196] 0 0
Shenzhen
Country [197] 0 0
China
State/province [197] 0 0
Siping
Country [198] 0 0
China
State/province [198] 0 0
Suzhou
Country [199] 0 0
China
State/province [199] 0 0
Tianjin
Country [200] 0 0
China
State/province [200] 0 0
Wenzhou
Country [201] 0 0
China
State/province [201] 0 0
Wuhan
Country [202] 0 0
China
State/province [202] 0 0
Xi'An
Country [203] 0 0
China
State/province [203] 0 0
Xuzhou
Country [204] 0 0
China
State/province [204] 0 0
Yanji
Country [205] 0 0
China
State/province [205] 0 0
Yueyang
Country [206] 0 0
China
State/province [206] 0 0
Zhanjiang
Country [207] 0 0
Colombia
State/province [207] 0 0
Armenia
Country [208] 0 0
Colombia
State/province [208] 0 0
Barranquilla
Country [209] 0 0
Colombia
State/province [209] 0 0
Bogota D.C.
Country [210] 0 0
Colombia
State/province [210] 0 0
Bogota
Country [211] 0 0
Colombia
State/province [211] 0 0
Cali
Country [212] 0 0
Colombia
State/province [212] 0 0
Cartagena
Country [213] 0 0
Colombia
State/province [213] 0 0
Espinal - Tolima
Country [214] 0 0
Colombia
State/province [214] 0 0
Floridablanca
Country [215] 0 0
Colombia
State/province [215] 0 0
Manizales
Country [216] 0 0
Colombia
State/province [216] 0 0
Medellin
Country [217] 0 0
Croatia
State/province [217] 0 0
Dubrovnik
Country [218] 0 0
Croatia
State/province [218] 0 0
Krapinske Toplice
Country [219] 0 0
Croatia
State/province [219] 0 0
Opatija
Country [220] 0 0
Croatia
State/province [220] 0 0
Rijeka
Country [221] 0 0
Croatia
State/province [221] 0 0
Slavonski Brod
Country [222] 0 0
Croatia
State/province [222] 0 0
Varazdin
Country [223] 0 0
Croatia
State/province [223] 0 0
Zagreb
Country [224] 0 0
Czechia
State/province [224] 0 0
Brno
Country [225] 0 0
Czechia
State/province [225] 0 0
Ceska Lipa
Country [226] 0 0
Czechia
State/province [226] 0 0
Cesky Krumlov
Country [227] 0 0
Czechia
State/province [227] 0 0
Hodonin
Country [228] 0 0
Czechia
State/province [228] 0 0
Hradec Kralove
Country [229] 0 0
Czechia
State/province [229] 0 0
Kladno
Country [230] 0 0
Czechia
State/province [230] 0 0
Kromeriz
Country [231] 0 0
Czechia
State/province [231] 0 0
Liberec
Country [232] 0 0
Czechia
State/province [232] 0 0
Marianske Lazne
Country [233] 0 0
Czechia
State/province [233] 0 0
Olomouc
Country [234] 0 0
Czechia
State/province [234] 0 0
Ostrava
Country [235] 0 0
Czechia
State/province [235] 0 0
Pardubice
Country [236] 0 0
Czechia
State/province [236] 0 0
Plzen
Country [237] 0 0
Czechia
State/province [237] 0 0
Praha 10
Country [238] 0 0
Czechia
State/province [238] 0 0
Praha 2
Country [239] 0 0
Czechia
State/province [239] 0 0
Praha 4
Country [240] 0 0
Czechia
State/province [240] 0 0
Praha 5 - Motol
Country [241] 0 0
Czechia
State/province [241] 0 0
Praha 5
Country [242] 0 0
Czechia
State/province [242] 0 0
Rakovnik
Country [243] 0 0
Czechia
State/province [243] 0 0
Zlin
Country [244] 0 0
Denmark
State/province [244] 0 0
Aabenraa
Country [245] 0 0
Denmark
State/province [245] 0 0
Aalborg
Country [246] 0 0
Denmark
State/province [246] 0 0
Aarhus N
Country [247] 0 0
Denmark
State/province [247] 0 0
Copenhagen
Country [248] 0 0
Denmark
State/province [248] 0 0
Glostrup
Country [249] 0 0
Denmark
State/province [249] 0 0
Hellerup
Country [250] 0 0
Denmark
State/province [250] 0 0
Herning
Country [251] 0 0
Denmark
State/province [251] 0 0
Hillerød
Country [252] 0 0
Denmark
State/province [252] 0 0
Holbaek
Country [253] 0 0
Denmark
State/province [253] 0 0
Hvidovre
Country [254] 0 0
Denmark
State/province [254] 0 0
Køge
Country [255] 0 0
Denmark
State/province [255] 0 0
Næstved
Country [256] 0 0
Denmark
State/province [256] 0 0
Odense C
Country [257] 0 0
Denmark
State/province [257] 0 0
Silkeborg
Country [258] 0 0
Denmark
State/province [258] 0 0
Slagelse
Country [259] 0 0
Denmark
State/province [259] 0 0
Vejle
Country [260] 0 0
Denmark
State/province [260] 0 0
Viborg
Country [261] 0 0
Estonia
State/province [261] 0 0
Pärnu
Country [262] 0 0
Estonia
State/province [262] 0 0
Tallinn
Country [263] 0 0
Estonia
State/province [263] 0 0
Tartu
Country [264] 0 0
Estonia
State/province [264] 0 0
Viljandimaa
Country [265] 0 0
Finland
State/province [265] 0 0
Helsinki
Country [266] 0 0
Finland
State/province [266] 0 0
Oulu
Country [267] 0 0
Finland
State/province [267] 0 0
Tampere
Country [268] 0 0
Finland
State/province [268] 0 0
Turku
Country [269] 0 0
France
State/province [269] 0 0
Besancon
Country [270] 0 0
France
State/province [270] 0 0
Brest Cedex
Country [271] 0 0
France
State/province [271] 0 0
Cambrai Cedex
Country [272] 0 0
France
State/province [272] 0 0
Clermont-Ferrand Cedex 1
Country [273] 0 0
France
State/province [273] 0 0
Compiegne
Country [274] 0 0
France
State/province [274] 0 0
Dijon
Country [275] 0 0
France
State/province [275] 0 0
Grenoble
Country [276] 0 0
France
State/province [276] 0 0
Limoges Cedex 1
Country [277] 0 0
France
State/province [277] 0 0
Marseille
Country [278] 0 0
France
State/province [278] 0 0
Massy
Country [279] 0 0
France
State/province [279] 0 0
Montfermeil
Country [280] 0 0
France
State/province [280] 0 0
Montpellier Cedex 5
Country [281] 0 0
France
State/province [281] 0 0
Nantes
Country [282] 0 0
France
State/province [282] 0 0
Nice Cedex 01
Country [283] 0 0
France
State/province [283] 0 0
Paris Cedex 12
Country [284] 0 0
France
State/province [284] 0 0
Paris
Country [285] 0 0
France
State/province [285] 0 0
Pau
Country [286] 0 0
France
State/province [286] 0 0
Pessac
Country [287] 0 0
France
State/province [287] 0 0
Rouen
Country [288] 0 0
France
State/province [288] 0 0
Strasbourg Cedex
Country [289] 0 0
Georgia
State/province [289] 0 0
Batumi
Country [290] 0 0
Georgia
State/province [290] 0 0
Kutaisi
Country [291] 0 0
Georgia
State/province [291] 0 0
Tbilisi
Country [292] 0 0
Germany
State/province [292] 0 0
Aachen
Country [293] 0 0
Germany
State/province [293] 0 0
Bad Krozingen
Country [294] 0 0
Germany
State/province [294] 0 0
Berlin
Country [295] 0 0
Germany
State/province [295] 0 0
Bernau
Country [296] 0 0
Germany
State/province [296] 0 0
Bielefeld
Country [297] 0 0
Germany
State/province [297] 0 0
Bonn
Country [298] 0 0
Germany
State/province [298] 0 0
Dortmund
Country [299] 0 0
Germany
State/province [299] 0 0
Dresden
Country [300] 0 0
Germany
State/province [300] 0 0
Eschweiler
Country [301] 0 0
Germany
State/province [301] 0 0
Essen
Country [302] 0 0
Germany
State/province [302] 0 0
Frankfurt Am Main
Country [303] 0 0
Germany
State/province [303] 0 0
Freiburg
Country [304] 0 0
Germany
State/province [304] 0 0
Halle/Saale
Country [305] 0 0
Germany
State/province [305] 0 0
Hamburg
Country [306] 0 0
Germany
State/province [306] 0 0
Hamm
Country [307] 0 0
Germany
State/province [307] 0 0
Haßloch
Country [308] 0 0
Germany
State/province [308] 0 0
Heidelberg
Country [309] 0 0
Germany
State/province [309] 0 0
Homburg/Saar
Country [310] 0 0
Germany
State/province [310] 0 0
Kassel
Country [311] 0 0
Germany
State/province [311] 0 0
Leipzig
Country [312] 0 0
Germany
State/province [312] 0 0
Limburg
Country [313] 0 0
Germany
State/province [313] 0 0
Lippstadt
Country [314] 0 0
Germany
State/province [314] 0 0
Lübeck
Country [315] 0 0
Germany
State/province [315] 0 0
Magdeburg
Country [316] 0 0
Germany
State/province [316] 0 0
Mainz
Country [317] 0 0
Germany
State/province [317] 0 0
Marburg
Country [318] 0 0
Germany
State/province [318] 0 0
Münster
Country [319] 0 0
Germany
State/province [319] 0 0
Nürnberg
Country [320] 0 0
Germany
State/province [320] 0 0
Peine
Country [321] 0 0
Germany
State/province [321] 0 0
Rotenburg An Der Fulda
Country [322] 0 0
Germany
State/province [322] 0 0
Rüdersdorf Bei Berlin
Country [323] 0 0
Germany
State/province [323] 0 0
Stuttgart
Country [324] 0 0
Germany
State/province [324] 0 0
Warendorf
Country [325] 0 0
Greece
State/province [325] 0 0
Athens
Country [326] 0 0
Greece
State/province [326] 0 0
Chios
Country [327] 0 0
Greece
State/province [327] 0 0
Haidari
Country [328] 0 0
Greece
State/province [328] 0 0
Heraklion
Country [329] 0 0
Greece
State/province [329] 0 0
Ioannina
Country [330] 0 0
Greece
State/province [330] 0 0
Marousi
Country [331] 0 0
Greece
State/province [331] 0 0
N. Ionia
Country [332] 0 0
Greece
State/province [332] 0 0
Patra
Country [333] 0 0
Greece
State/province [333] 0 0
Thessaloniki
Country [334] 0 0
Guatemala
State/province [334] 0 0
Guatemala
Country [335] 0 0
Hong Kong
State/province [335] 0 0
Hong Kong
Country [336] 0 0
Hong Kong
State/province [336] 0 0
Shatin, Nt
Country [337] 0 0
Hungary
State/province [337] 0 0
Balatonfüred
Country [338] 0 0
Hungary
State/province [338] 0 0
Budapest
Country [339] 0 0
Hungary
State/province [339] 0 0
Debrecen
Country [340] 0 0
Hungary
State/province [340] 0 0
Eger
Country [341] 0 0
Hungary
State/province [341] 0 0
Gyula
Country [342] 0 0
Hungary
State/province [342] 0 0
Pécs
Country [343] 0 0
Hungary
State/province [343] 0 0
Szeged
Country [344] 0 0
Hungary
State/province [344] 0 0
Szekesfehervar
Country [345] 0 0
Hungary
State/province [345] 0 0
Szombathely
Country [346] 0 0
Hungary
State/province [346] 0 0
Zalaegerszeg
Country [347] 0 0
India
State/province [347] 0 0
Ahmedabad
Country [348] 0 0
India
State/province [348] 0 0
Aurangabad
Country [349] 0 0
India
State/province [349] 0 0
Bangalore
Country [350] 0 0
India
State/province [350] 0 0
Belgaum
Country [351] 0 0
India
State/province [351] 0 0
Bikaner
Country [352] 0 0
India
State/province [352] 0 0
Chennai
Country [353] 0 0
India
State/province [353] 0 0
Delhi
Country [354] 0 0
India
State/province [354] 0 0
Gurgaon
Country [355] 0 0
India
State/province [355] 0 0
Hyderabad
Country [356] 0 0
India
State/province [356] 0 0
Jaipur
Country [357] 0 0
India
State/province [357] 0 0
Karad
Country [358] 0 0
India
State/province [358] 0 0
Karamsad
Country [359] 0 0
India
State/province [359] 0 0
Kochi
Country [360] 0 0
India
State/province [360] 0 0
Kolhapur
Country [361] 0 0
India
State/province [361] 0 0
Kolkata
Country [362] 0 0
India
State/province [362] 0 0
Ludhiana
Country [363] 0 0
India
State/province [363] 0 0
Mangalore
Country [364] 0 0
India
State/province [364] 0 0
Mumbai
Country [365] 0 0
India
State/province [365] 0 0
Mysore
Country [366] 0 0
India
State/province [366] 0 0
Nagpur
Country [367] 0 0
India
State/province [367] 0 0
Nashik
Country [368] 0 0
India
State/province [368] 0 0
New Delhi
Country [369] 0 0
India
State/province [369] 0 0
Panaji
Country [370] 0 0
India
State/province [370] 0 0
Pune
Country [371] 0 0
India
State/province [371] 0 0
Secunderabad, Hyderabad
Country [372] 0 0
India
State/province [372] 0 0
Secunderabad
Country [373] 0 0
India
State/province [373] 0 0
Surat
Country [374] 0 0
India
State/province [374] 0 0
Vijayawada
Country [375] 0 0
India
State/province [375] 0 0
Vijaywada
Country [376] 0 0
India
State/province [376] 0 0
Visakhapatnam
Country [377] 0 0
India
State/province [377] 0 0
Vishkhapattanam
Country [378] 0 0
India
State/province [378] 0 0
Wardha
Country [379] 0 0
Israel
State/province [379] 0 0
Afula
Country [380] 0 0
Israel
State/province [380] 0 0
Ashkelon
Country [381] 0 0
Israel
State/province [381] 0 0
Beer Sheva
Country [382] 0 0
Israel
State/province [382] 0 0
Haifa
Country [383] 0 0
Israel
State/province [383] 0 0
Holon
Country [384] 0 0
Israel
State/province [384] 0 0
Jerusalem
Country [385] 0 0
Israel
State/province [385] 0 0
Kfar Saba
Country [386] 0 0
Israel
State/province [386] 0 0
Nahariya
Country [387] 0 0
Israel
State/province [387] 0 0
Nazareth
Country [388] 0 0
Israel
State/province [388] 0 0
Petah-Tikva
Country [389] 0 0
Israel
State/province [389] 0 0
Rehovot
Country [390] 0 0
Israel
State/province [390] 0 0
Safed
Country [391] 0 0
Israel
State/province [391] 0 0
Tel Aviv
Country [392] 0 0
Israel
State/province [392] 0 0
Tel Hashomer
Country [393] 0 0
Israel
State/province [393] 0 0
Tiberias
Country [394] 0 0
Israel
State/province [394] 0 0
Tzrifin
Country [395] 0 0
Italy
State/province [395] 0 0
Augusta
Country [396] 0 0
Italy
State/province [396] 0 0
Bergamo
Country [397] 0 0
Italy
State/province [397] 0 0
Brescia
Country [398] 0 0
Italy
State/province [398] 0 0
Ferrara
Country [399] 0 0
Italy
State/province [399] 0 0
Forlì
Country [400] 0 0
Italy
State/province [400] 0 0
Livorno
Country [401] 0 0
Italy
State/province [401] 0 0
Massa
Country [402] 0 0
Italy
State/province [402] 0 0
Milano
Country [403] 0 0
Italy
State/province [403] 0 0
Monza
Country [404] 0 0
Italy
State/province [404] 0 0
Napoli
Country [405] 0 0
Italy
State/province [405] 0 0
Novara
Country [406] 0 0
Italy
State/province [406] 0 0
Osio Sotto
Country [407] 0 0
Italy
State/province [407] 0 0
Palermo
Country [408] 0 0
Italy
State/province [408] 0 0
Perugia
Country [409] 0 0
Italy
State/province [409] 0 0
Rho
Country [410] 0 0
Italy
State/province [410] 0 0
Rimini
Country [411] 0 0
Italy
State/province [411] 0 0
Roma
Country [412] 0 0
Italy
State/province [412] 0 0
Seriate
Country [413] 0 0
Italy
State/province [413] 0 0
Treviso
Country [414] 0 0
Italy
State/province [414] 0 0
Vittorio Veneto
Country [415] 0 0
Japan
State/province [415] 0 0
Amagasaki-Shi
Country [416] 0 0
Japan
State/province [416] 0 0
Fukuoka-Shi
Country [417] 0 0
Japan
State/province [417] 0 0
Hachioji-Shi
Country [418] 0 0
Japan
State/province [418] 0 0
Higashihiroshima-Shi
Country [419] 0 0
Japan
State/province [419] 0 0
Higashiibaraki-Gun
Country [420] 0 0
Japan
State/province [420] 0 0
Hiroshima-Shi
Country [421] 0 0
Japan
State/province [421] 0 0
Itabashi-Ku
Country [422] 0 0
Japan
State/province [422] 0 0
Izumisano-Shi
Country [423] 0 0
Japan
State/province [423] 0 0
Kanazawa-Shi
Country [424] 0 0
Japan
State/province [424] 0 0
Kitakyushu-Shi
Country [425] 0 0
Japan
State/province [425] 0 0
Kobe-Shi
Country [426] 0 0
Japan
State/province [426] 0 0
Koga-Shi
Country [427] 0 0
Japan
State/province [427] 0 0
Komatsu-Shi
Country [428] 0 0
Japan
State/province [428] 0 0
Komatsushima-Shi
Country [429] 0 0
Japan
State/province [429] 0 0
Kumamoto-Shi
Country [430] 0 0
Japan
State/province [430] 0 0
Kure-Shi
Country [431] 0 0
Japan
State/province [431] 0 0
Kurume-Shi
Country [432] 0 0
Japan
State/province [432] 0 0
Kusatsu-Shi
Country [433] 0 0
Japan
State/province [433] 0 0
Kyoto City
Country [434] 0 0
Japan
State/province [434] 0 0
Minato-Ku
Country [435] 0 0
Japan
State/province [435] 0 0
Morioka-Shi
Country [436] 0 0
Japan
State/province [436] 0 0
Nagoya-Shi
Country [437] 0 0
Japan
State/province [437] 0 0
Nerima-Ku
Country [438] 0 0
Japan
State/province [438] 0 0
Osaka-Shi
Country [439] 0 0
Japan
State/province [439] 0 0
Sagamihara-Shi
Country [440] 0 0
Japan
State/province [440] 0 0
Sapporo-Shi
Country [441] 0 0
Japan
State/province [441] 0 0
Shinagawa-Ku
Country [442] 0 0
Japan
State/province [442] 0 0
Suita-Shi
Country [443] 0 0
Japan
State/province [443] 0 0
Tokushima-Shi
Country [444] 0 0
Japan
State/province [444] 0 0
Urasoe-Shi
Country [445] 0 0
Japan
State/province [445] 0 0
Yokohama-Shi
Country [446] 0 0
Korea, Republic of
State/province [446] 0 0
Busan
Country [447] 0 0
Korea, Republic of
State/province [447] 0 0
Daegu
Country [448] 0 0
Korea, Republic of
State/province [448] 0 0
Goyang-Si
Country [449] 0 0
Korea, Republic of
State/province [449] 0 0
Gwangju
Country [450] 0 0
Korea, Republic of
State/province [450] 0 0
Seongnam
Country [451] 0 0
Korea, Republic of
State/province [451] 0 0
Seoul
Country [452] 0 0
Korea, Republic of
State/province [452] 0 0
Suwon
Country [453] 0 0
Korea, Republic of
State/province [453] 0 0
Wonju
Country [454] 0 0
Latvia
State/province [454] 0 0
Daugavpils
Country [455] 0 0
Latvia
State/province [455] 0 0
Liepaja
Country [456] 0 0
Latvia
State/province [456] 0 0
Riga
Country [457] 0 0
Latvia
State/province [457] 0 0
Ventspils
Country [458] 0 0
Lithuania
State/province [458] 0 0
Kaunas
Country [459] 0 0
Lithuania
State/province [459] 0 0
Klaipeda
Country [460] 0 0
Lithuania
State/province [460] 0 0
Vilnius
Country [461] 0 0
Macedonia, The Former Yugoslav Republic of
State/province [461] 0 0
Bitola
Country [462] 0 0
Macedonia, The Former Yugoslav Republic of
State/province [462] 0 0
Shtip
Country [463] 0 0
Macedonia, The Former Yugoslav Republic of
State/province [463] 0 0
Skopje
Country [464] 0 0
Macedonia, The Former Yugoslav Republic of
State/province [464] 0 0
Tetovo
Country [465] 0 0
Malaysia
State/province [465] 0 0
Batu Caves
Country [466] 0 0
Malaysia
State/province [466] 0 0
Kota Bharu
Country [467] 0 0
Malaysia
State/province [467] 0 0
Kota Kinabalu
Country [468] 0 0
Malaysia
State/province [468] 0 0
Kuala Lumpur
Country [469] 0 0
Malaysia
State/province [469] 0 0
Kuching
Country [470] 0 0
Malaysia
State/province [470] 0 0
Sungai Buloh
Country [471] 0 0
Mexico
State/province [471] 0 0
Aguascalientes
Country [472] 0 0
Mexico
State/province [472] 0 0
Culiacan
Country [473] 0 0
Mexico
State/province [473] 0 0
Durango
Country [474] 0 0
Mexico
State/province [474] 0 0
Guadalajara
Country [475] 0 0
Mexico
State/province [475] 0 0
Jalapa
Country [476] 0 0
Mexico
State/province [476] 0 0
Mexico D.F.
Country [477] 0 0
Mexico
State/province [477] 0 0
Mexico Df
Country [478] 0 0
Mexico
State/province [478] 0 0
Mexico
Country [479] 0 0
Mexico
State/province [479] 0 0
Monterrey
Country [480] 0 0
Mexico
State/province [480] 0 0
Morelia
Country [481] 0 0
Mexico
State/province [481] 0 0
Oaxaca
Country [482] 0 0
Mexico
State/province [482] 0 0
Querétaro
Country [483] 0 0
Mexico
State/province [483] 0 0
San Luis Potosi
Country [484] 0 0
Mexico
State/province [484] 0 0
Tijuana
Country [485] 0 0
Mexico
State/province [485] 0 0
Toluca
Country [486] 0 0
Netherlands
State/province [486] 0 0
Alkmaar
Country [487] 0 0
Netherlands
State/province [487] 0 0
Amsterdam
Country [488] 0 0
Netherlands
State/province [488] 0 0
Apeldoorn
Country [489] 0 0
Netherlands
State/province [489] 0 0
Arnhem
Country [490] 0 0
Netherlands
State/province [490] 0 0
Breda
Country [491] 0 0
Netherlands
State/province [491] 0 0
Delft
Country [492] 0 0
Netherlands
State/province [492] 0 0
Eindhoven
Country [493] 0 0
Netherlands
State/province [493] 0 0
Goes
Country [494] 0 0
Netherlands
State/province [494] 0 0
Gouda
Country [495] 0 0
Netherlands
State/province [495] 0 0
Groningen
Country [496] 0 0
Netherlands
State/province [496] 0 0
Haarlem
Country [497] 0 0
Netherlands
State/province [497] 0 0
Hardenberg
Country [498] 0 0
Netherlands
State/province [498] 0 0
Heerenveen
Country [499] 0 0
Netherlands
State/province [499] 0 0
Hoorn
Country [500] 0 0
Netherlands
State/province [500] 0 0
Leeuwarden
Country [501] 0 0
Netherlands
State/province [501] 0 0
Leiden
Country [502] 0 0
Netherlands
State/province [502] 0 0
Meppel
Country [503] 0 0
Netherlands
State/province [503] 0 0
Nieuwegein
Country [504] 0 0
Netherlands
State/province [504] 0 0
Nijmegen
Country [505] 0 0
Netherlands
State/province [505] 0 0
Purmerend
Country [506] 0 0
Netherlands
State/province [506] 0 0
Roosendaal
Country [507] 0 0
Netherlands
State/province [507] 0 0
Rotterdam
Country [508] 0 0
Netherlands
State/province [508] 0 0
Sneek
Country [509] 0 0
Netherlands
State/province [509] 0 0
Tiel
Country [510] 0 0
Netherlands
State/province [510] 0 0
Tilburg
Country [511] 0 0
Netherlands
State/province [511] 0 0
Uden
Country [512] 0 0
Netherlands
State/province [512] 0 0
Venlo
Country [513] 0 0
Netherlands
State/province [513] 0 0
Zaandam
Country [514] 0 0
Netherlands
State/province [514] 0 0
Zutphen
Country [515] 0 0
Netherlands
State/province [515] 0 0
Zwolle
Country [516] 0 0
New Zealand
State/province [516] 0 0
Auckland
Country [517] 0 0
New Zealand
State/province [517] 0 0
Christchurch
Country [518] 0 0
New Zealand
State/province [518] 0 0
Dunedin
Country [519] 0 0
New Zealand
State/province [519] 0 0
Hamilton
Country [520] 0 0
New Zealand
State/province [520] 0 0
Lower Hutt
Country [521] 0 0
New Zealand
State/province [521] 0 0
Nelson
Country [522] 0 0
New Zealand
State/province [522] 0 0
New Plymouth
Country [523] 0 0
New Zealand
State/province [523] 0 0
Otahuhu
Country [524] 0 0
New Zealand
State/province [524] 0 0
Palmerston North
Country [525] 0 0
New Zealand
State/province [525] 0 0
Rotorua
Country [526] 0 0
New Zealand
State/province [526] 0 0
Takapuna
Country [527] 0 0
New Zealand
State/province [527] 0 0
Wellington
Country [528] 0 0
Norway
State/province [528] 0 0
Arendal
Country [529] 0 0
Norway
State/province [529] 0 0
Bergen
Country [530] 0 0
Norway
State/province [530] 0 0
Hamar
Country [531] 0 0
Norway
State/province [531] 0 0
Kongsvinger
Country [532] 0 0
Norway
State/province [532] 0 0
Oslo
Country [533] 0 0
Norway
State/province [533] 0 0
Stavanger
Country [534] 0 0
Norway
State/province [534] 0 0
Svelvik
Country [535] 0 0
Norway
State/province [535] 0 0
Tynset
Country [536] 0 0
Peru
State/province [536] 0 0
Arequipa
Country [537] 0 0
Peru
State/province [537] 0 0
Callao
Country [538] 0 0
Peru
State/province [538] 0 0
Cuzco
Country [539] 0 0
Peru
State/province [539] 0 0
Ica
Country [540] 0 0
Peru
State/province [540] 0 0
Lima
Country [541] 0 0
Peru
State/province [541] 0 0
Piura
Country [542] 0 0
Peru
State/province [542] 0 0
Trujillo
Country [543] 0 0
Philippines
State/province [543] 0 0
Cavite
Country [544] 0 0
Philippines
State/province [544] 0 0
Cebu City
Country [545] 0 0
Philippines
State/province [545] 0 0
Davao City
Country [546] 0 0
Philippines
State/province [546] 0 0
Davao
Country [547] 0 0
Philippines
State/province [547] 0 0
Iloilo City
Country [548] 0 0
Philippines
State/province [548] 0 0
Makati City
Country [549] 0 0
Philippines
State/province [549] 0 0
Manila
Country [550] 0 0
Philippines
State/province [550] 0 0
Quezon City
Country [551] 0 0
Philippines
State/province [551] 0 0
Quezon
Country [552] 0 0
Philippines
State/province [552] 0 0
San Juan
Country [553] 0 0
Poland
State/province [553] 0 0
Bydgoszcz
Country [554] 0 0
Poland
State/province [554] 0 0
Chrzanow
Country [555] 0 0
Poland
State/province [555] 0 0
Czeladz
Country [556] 0 0
Poland
State/province [556] 0 0
Gdansk
Country [557] 0 0
Poland
State/province [557] 0 0
Gdynia
Country [558] 0 0
Poland
State/province [558] 0 0
Grodzisk Mazowiecki
Country [559] 0 0
Poland
State/province [559] 0 0
Jelenia Gora
Country [560] 0 0
Poland
State/province [560] 0 0
Krakow
Country [561] 0 0
Poland
State/province [561] 0 0
Leczna
Country [562] 0 0
Poland
State/province [562] 0 0
Legnica
Country [563] 0 0
Poland
State/province [563] 0 0
Lodz
Country [564] 0 0
Poland
State/province [564] 0 0
Lubin
Country [565] 0 0
Poland
State/province [565] 0 0
Olawa
Country [566] 0 0
Poland
State/province [566] 0 0
Olsztyn
Country [567] 0 0
Poland
State/province [567] 0 0
Plock
Country [568] 0 0
Poland
State/province [568] 0 0
Poznan
Country [569] 0 0
Poland
State/province [569] 0 0
Pulawy
Country [570] 0 0
Poland
State/province [570] 0 0
Skierniewice
Country [571] 0 0
Poland
State/province [571] 0 0
Sobotka
Country [572] 0 0
Poland
State/province [572] 0 0
Sokolka
Country [573] 0 0
Poland
State/province [573] 0 0
Swidnik
Country [574] 0 0
Poland
State/province [574] 0 0
Szczecin
Country [575] 0 0
Poland
State/province [575] 0 0
Torun
Country [576] 0 0
Poland
State/province [576] 0 0
W?Grów
Country [577] 0 0
Poland
State/province [577] 0 0
Warszawa
Country [578] 0 0
Poland
State/province [578] 0 0
Wroclaw
Country [579] 0 0
Portugal
State/province [579] 0 0
Almada
Country [580] 0 0
Portugal
State/province [580] 0 0
Aveiro
Country [581] 0 0
Portugal
State/province [581] 0 0
Coimbra
Country [582] 0 0
Portugal
State/province [582] 0 0
Leiria
Country [583] 0 0
Portugal
State/province [583] 0 0
Ponta Delgada
Country [584] 0 0
Portugal
State/province [584] 0 0
Setubal
Country [585] 0 0
Portugal
State/province [585] 0 0
Vila Franca De Xira
Country [586] 0 0
Portugal
State/province [586] 0 0
Vila Nova Gaia
Country [587] 0 0
Romania
State/province [587] 0 0
Braila
Country [588] 0 0
Romania
State/province [588] 0 0
Bucharest
Country [589] 0 0
Romania
State/province [589] 0 0
Bucuresti
Country [590] 0 0
Romania
State/province [590] 0 0
Buzau
Country [591] 0 0
Romania
State/province [591] 0 0
Codlea
Country [592] 0 0
Romania
State/province [592] 0 0
Constanta
Country [593] 0 0
Romania
State/province [593] 0 0
Craiova
Country [594] 0 0
Romania
State/province [594] 0 0
Focsani
Country [595] 0 0
Romania
State/province [595] 0 0
Iasi
Country [596] 0 0
Romania
State/province [596] 0 0
Targoviste
Country [597] 0 0
Romania
State/province [597] 0 0
Targu Mures
Country [598] 0 0
Romania
State/province [598] 0 0
Timisoara
Country [599] 0 0
Russian Federation
State/province [599] 0 0
Barnaul
Country [600] 0 0
Russian Federation
State/province [600] 0 0
Kazan
Country [601] 0 0
Russian Federation
State/province [601] 0 0
Kemerovo
Country [602] 0 0
Russian Federation
State/province [602] 0 0
Krasnodar
Country [603] 0 0
Russian Federation
State/province [603] 0 0
Moscow
Country [604] 0 0
Russian Federation
State/province [604] 0 0
Nizhny Novgorod
Country [605] 0 0
Russian Federation
State/province [605] 0 0
Novosibirsk
Country [606] 0 0
Russian Federation
State/province [606] 0 0
Omsk
Country [607] 0 0
Russian Federation
State/province [607] 0 0
Perm
Country [608] 0 0
Russian Federation
State/province [608] 0 0
Rostov-Na-Donu
Country [609] 0 0
Russian Federation
State/province [609] 0 0
Ryazan
Country [610] 0 0
Russian Federation
State/province [610] 0 0
Saint - Petersburg
Country [611] 0 0
Russian Federation
State/province [611] 0 0
Saint Petersburg
Country [612] 0 0
Russian Federation
State/province [612] 0 0
Saint-Petersburg
Country [613] 0 0
Russian Federation
State/province [613] 0 0
Saratov
Country [614] 0 0
Russian Federation
State/province [614] 0 0
St-Petersburg
Country [615] 0 0
Russian Federation
State/province [615] 0 0
Tomsk
Country [616] 0 0
Russian Federation
State/province [616] 0 0
Tyumen
Country [617] 0 0
Russian Federation
State/province [617] 0 0
Voronezh
Country [618] 0 0
Russian Federation
State/province [618] 0 0
Yaroslavl
Country [619] 0 0
Serbia
State/province [619] 0 0
Belgrade
Country [620] 0 0
Serbia
State/province [620] 0 0
Kragujevac
Country [621] 0 0
Serbia
State/province [621] 0 0
Leskovac
Country [622] 0 0
Serbia
State/province [622] 0 0
Niska Banja
Country [623] 0 0
Serbia
State/province [623] 0 0
Nis
Country [624] 0 0
Serbia
State/province [624] 0 0
Pancevo
Country [625] 0 0
Serbia
State/province [625] 0 0
Sremska Kamenica
Country [626] 0 0
Serbia
State/province [626] 0 0
Sremska Mitrovica
Country [627] 0 0
Serbia
State/province [627] 0 0
Valjevo
Country [628] 0 0
Singapore
State/province [628] 0 0
Singapore
Country [629] 0 0
Slovakia
State/province [629] 0 0
Bardejov
Country [630] 0 0
Slovakia
State/province [630] 0 0
Bratislava
Country [631] 0 0
Slovakia
State/province [631] 0 0
Dolny Kubin
Country [632] 0 0
Slovakia
State/province [632] 0 0
Kosice
Country [633] 0 0
Slovakia
State/province [633] 0 0
Kralovsky Chlmec
Country [634] 0 0
Slovakia
State/province [634] 0 0
Lucenec
Country [635] 0 0
Slovakia
State/province [635] 0 0
Nitra
Country [636] 0 0
Slovakia
State/province [636] 0 0
Presov
Country [637] 0 0
Slovakia
State/province [637] 0 0
Svidnik
Country [638] 0 0
Slovakia
State/province [638] 0 0
Trebisov
Country [639] 0 0
Slovakia
State/province [639] 0 0
Zilina
Country [640] 0 0
Slovenia
State/province [640] 0 0
Celje
Country [641] 0 0
Slovenia
State/province [641] 0 0
Izola
Country [642] 0 0
Slovenia
State/province [642] 0 0
Jesenice
Country [643] 0 0
Slovenia
State/province [643] 0 0
Ljubljana
Country [644] 0 0
South Africa
State/province [644] 0 0
Alberton
Country [645] 0 0
South Africa
State/province [645] 0 0
Bellville
Country [646] 0 0
South Africa
State/province [646] 0 0
Bloemfontein
Country [647] 0 0
South Africa
State/province [647] 0 0
Cape Town
Country [648] 0 0
South Africa
State/province [648] 0 0
Chatsworth
Country [649] 0 0
South Africa
State/province [649] 0 0
Durban
Country [650] 0 0
South Africa
State/province [650] 0 0
Johannesburg
Country [651] 0 0
South Africa
State/province [651] 0 0
Kempton Park
Country [652] 0 0
South Africa
State/province [652] 0 0
Kimberley
Country [653] 0 0
South Africa
State/province [653] 0 0
Kuils River
Country [654] 0 0
South Africa
State/province [654] 0 0
Parow
Country [655] 0 0
South Africa
State/province [655] 0 0
Pretoria
Country [656] 0 0
South Africa
State/province [656] 0 0
Stellenbosch
Country [657] 0 0
South Africa
State/province [657] 0 0
Tongaat
Country [658] 0 0
South Africa
State/province [658] 0 0
Western Cape
Country [659] 0 0
South Africa
State/province [659] 0 0
Worcester
Country [660] 0 0
Spain
State/province [660] 0 0
Alcalá De Henares
Country [661] 0 0
Spain
State/province [661] 0 0
Almería
Country [662] 0 0
Spain
State/province [662] 0 0
Barcelona
Country [663] 0 0
Spain
State/province [663] 0 0
Cáceres
Country [664] 0 0
Spain
State/province [664] 0 0
Córdoba
Country [665] 0 0
Spain
State/province [665] 0 0
Fuenlabrada
Country [666] 0 0
Spain
State/province [666] 0 0
Girona
Country [667] 0 0
Spain
State/province [667] 0 0
Granada
Country [668] 0 0
Spain
State/province [668] 0 0
Guadalajara
Country [669] 0 0
Spain
State/province [669] 0 0
Hospitalet De Llobregat
Country [670] 0 0
Spain
State/province [670] 0 0
Huelva
Country [671] 0 0
Spain
State/province [671] 0 0
León
Country [672] 0 0
Spain
State/province [672] 0 0
Lleida
Country [673] 0 0
Spain
State/province [673] 0 0
Lugo
Country [674] 0 0
Spain
State/province [674] 0 0
Madrid
Country [675] 0 0
Spain
State/province [675] 0 0
Majadahonda
Country [676] 0 0
Spain
State/province [676] 0 0
Murcia
Country [677] 0 0
Spain
State/province [677] 0 0
Málaga
Country [678] 0 0
Spain
State/province [678] 0 0
Oviedo
Country [679] 0 0
Spain
State/province [679] 0 0
Sabadell
Country [680] 0 0
Spain
State/province [680] 0 0
San Sebastian De Los Reyes
Country [681] 0 0
Spain
State/province [681] 0 0
Santander
Country [682] 0 0
Spain
State/province [682] 0 0
Santiago De Compostela
Country [683] 0 0
Spain
State/province [683] 0 0
Sevilla
Country [684] 0 0
Spain
State/province [684] 0 0
Tarragona
Country [685] 0 0
Spain
State/province [685] 0 0
Valencia
Country [686] 0 0
Spain
State/province [686] 0 0
Valladolid
Country [687] 0 0
Spain
State/province [687] 0 0
Vigo
Country [688] 0 0
Spain
State/province [688] 0 0
Zaragoza
Country [689] 0 0
Sri Lanka
State/province [689] 0 0
Colombo 7
Country [690] 0 0
Sri Lanka
State/province [690] 0 0
Colombo 8
Country [691] 0 0
Sri Lanka
State/province [691] 0 0
Colombo
Country [692] 0 0
Sri Lanka
State/province [692] 0 0
Kandy
Country [693] 0 0
Sri Lanka
State/province [693] 0 0
Kurunegala
Country [694] 0 0
Sri Lanka
State/province [694] 0 0
Ragama
Country [695] 0 0
Sweden
State/province [695] 0 0
Falun
Country [696] 0 0
Sweden
State/province [696] 0 0
Göteborg
Country [697] 0 0
Sweden
State/province [697] 0 0
Halmstad
Country [698] 0 0
Sweden
State/province [698] 0 0
Karlshamn
Country [699] 0 0
Sweden
State/province [699] 0 0
Karlskrona
Country [700] 0 0
Sweden
State/province [700] 0 0
Kristianstad
Country [701] 0 0
Sweden
State/province [701] 0 0
Köping
Country [702] 0 0
Sweden
State/province [702] 0 0
Malmö
Country [703] 0 0
Sweden
State/province [703] 0 0
Mölndal
Country [704] 0 0
Sweden
State/province [704] 0 0
Stockholm
Country [705] 0 0
Sweden
State/province [705] 0 0
Sundsvall
Country [706] 0 0
Sweden
State/province [706] 0 0
Uppsala
Country [707] 0 0
Switzerland
State/province [707] 0 0
Basel
Country [708] 0 0
Switzerland
State/province [708] 0 0
Geneve
Country [709] 0 0
Switzerland
State/province [709] 0 0
Lugano
Country [710] 0 0
Switzerland
State/province [710] 0 0
Zürich
Country [711] 0 0
Taiwan
State/province [711] 0 0
Changhua
Country [712] 0 0
Taiwan
State/province [712] 0 0
Division Of Cardiology
Country [713] 0 0
Taiwan
State/province [713] 0 0
Hsinchu
Country [714] 0 0
Taiwan
State/province [714] 0 0
Kaohsiung
Country [715] 0 0
Taiwan
State/province [715] 0 0
Taichung
Country [716] 0 0
Taiwan
State/province [716] 0 0
Tainan
Country [717] 0 0
Taiwan
State/province [717] 0 0
Taipei
Country [718] 0 0
Taiwan
State/province [718] 0 0
Taoyuan Hsien
Country [719] 0 0
Taiwan
State/province [719] 0 0
Yunlin
Country [720] 0 0
Thailand
State/province [720] 0 0
Bangkok-Noi
Country [721] 0 0
Thailand
State/province [721] 0 0
Bangkok
Country [722] 0 0
Thailand
State/province [722] 0 0
Hat Yai
Country [723] 0 0
Thailand
State/province [723] 0 0
Klong Luang
Country [724] 0 0
Thailand
State/province [724] 0 0
Moung
Country [725] 0 0
Thailand
State/province [725] 0 0
Muang
Country [726] 0 0
Thailand
State/province [726] 0 0
Nonthaburi
Country [727] 0 0
Thailand
State/province [727] 0 0
Pratumwan
Country [728] 0 0
Turkey
State/province [728] 0 0
Adana
Country [729] 0 0
Turkey
State/province [729] 0 0
Ankara
Country [730] 0 0
Turkey
State/province [730] 0 0
Bursa
Country [731] 0 0
Turkey
State/province [731] 0 0
Eskisehir
Country [732] 0 0
Turkey
State/province [732] 0 0
Istanbul
Country [733] 0 0
Turkey
State/province [733] 0 0
Izmir
Country [734] 0 0
Turkey
State/province [734] 0 0
Kocaeli
Country [735] 0 0
Turkey
State/province [735] 0 0
Mersin
Country [736] 0 0
Ukraine
State/province [736] 0 0
Chernivtsi
Country [737] 0 0
Ukraine
State/province [737] 0 0
Dnipropetrovsk
Country [738] 0 0
Ukraine
State/province [738] 0 0
Donetsk
Country [739] 0 0
Ukraine
State/province [739] 0 0
Ivano-Frankivsk
Country [740] 0 0
Ukraine
State/province [740] 0 0
Kharkiv
Country [741] 0 0
Ukraine
State/province [741] 0 0
Khmelnytskyi
Country [742] 0 0
Ukraine
State/province [742] 0 0
Kiev
Country [743] 0 0
Ukraine
State/province [743] 0 0
Kyiv
Country [744] 0 0
Ukraine
State/province [744] 0 0
Lutsk
Country [745] 0 0
Ukraine
State/province [745] 0 0
Lviv
Country [746] 0 0
Ukraine
State/province [746] 0 0
Mykolaiv
Country [747] 0 0
Ukraine
State/province [747] 0 0
Odesa
Country [748] 0 0
Ukraine
State/province [748] 0 0
Odessa
Country [749] 0 0
Ukraine
State/province [749] 0 0
Simferopol
Country [750] 0 0
Ukraine
State/province [750] 0 0
Sumy
Country [751] 0 0
Ukraine
State/province [751] 0 0
Uzhgorod
Country [752] 0 0
Ukraine
State/province [752] 0 0
Vinnitsya
Country [753] 0 0
Ukraine
State/province [753] 0 0
Vinnytsia
Country [754] 0 0
Ukraine
State/province [754] 0 0
Zaporizhia
Country [755] 0 0
Ukraine
State/province [755] 0 0
Zhytomyr
Country [756] 0 0
United Kingdom
State/province [756] 0 0
Basildon
Country [757] 0 0
United Kingdom
State/province [757] 0 0
Birmingham
Country [758] 0 0
United Kingdom
State/province [758] 0 0
Bournemouth
Country [759] 0 0
United Kingdom
State/province [759] 0 0
Bradford
Country [760] 0 0
United Kingdom
State/province [760] 0 0
Burton On Trent
Country [761] 0 0
United Kingdom
State/province [761] 0 0
Cardiff
Country [762] 0 0
United Kingdom
State/province [762] 0 0
Chertsey
Country [763] 0 0
United Kingdom
State/province [763] 0 0
Chesterfield
Country [764] 0 0
United Kingdom
State/province [764] 0 0
Chichester
Country [765] 0 0
United Kingdom
State/province [765] 0 0
Cumbria
Country [766] 0 0
United Kingdom
State/province [766] 0 0
Dudley
Country [767] 0 0
United Kingdom
State/province [767] 0 0
Harrow
Country [768] 0 0
United Kingdom
State/province [768] 0 0
High Wycombe
Country [769] 0 0
United Kingdom
State/province [769] 0 0
Hull
Country [770] 0 0
United Kingdom
State/province [770] 0 0
London
Country [771] 0 0
United Kingdom
State/province [771] 0 0
Manchester
Country [772] 0 0
United Kingdom
State/province [772] 0 0
Newcastle Upon Tyne
Country [773] 0 0
United Kingdom
State/province [773] 0 0
Northampton
Country [774] 0 0
United Kingdom
State/province [774] 0 0
Peterborough
Country [775] 0 0
United Kingdom
State/province [775] 0 0
Plymouth
Country [776] 0 0
United Kingdom
State/province [776] 0 0
Portadown
Country [777] 0 0
United Kingdom
State/province [777] 0 0
Portsmouth
Country [778] 0 0
United Kingdom
State/province [778] 0 0
Redhill
Country [779] 0 0
United Kingdom
State/province [779] 0 0
Rhyl
Country [780] 0 0
United Kingdom
State/province [780] 0 0
Romford
Country [781] 0 0
United Kingdom
State/province [781] 0 0
Rotherham
Country [782] 0 0
United Kingdom
State/province [782] 0 0
Sheffield
Country [783] 0 0
United Kingdom
State/province [783] 0 0
South Shields
Country [784] 0 0
United Kingdom
State/province [784] 0 0
St Leonards
Country [785] 0 0
United Kingdom
State/province [785] 0 0
Stoke-On-Trent
Country [786] 0 0
United Kingdom
State/province [786] 0 0
Sunderland
Country [787] 0 0
United Kingdom
State/province [787] 0 0
Truro
Country [788] 0 0
United Kingdom
State/province [788] 0 0
Wigan
Country [789] 0 0
United Kingdom
State/province [789] 0 0
Worcester

Funding & Sponsors
Primary sponsor type
Commercial sector/industry
Name
Sanofi
Address
Country
Other collaborator category [1] 0 0
Commercial sector/industry
Name [1] 0 0
Regeneron Pharmaceuticals
Address [1] 0 0
Country [1] 0 0

Ethics approval
Ethics application status

Summary
Brief summary
Trial website
Trial related presentations / publications
Public notes

Contacts
Principal investigator
Name 0 0
Clinical Sciences & Operations
Address 0 0
Sanofi
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for public queries
Name 0 0
Address 0 0
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for scientific queries

No information has been provided regarding IPD availability


What supporting documents are/will be available?

Results publications and other study-related documents

No documents have been uploaded by study researchers.