ANZCTR - Registration

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Trial registered on ANZCTR

Registration number

ACTRN12617000640303

Ethics application status

Approved

Date submitted

28/04/2017

Date registered

2/05/2017

Date last updated

2/05/2017

Type of registration

Retrospectively registered

Titles & IDs

Public title

Perth Longitudinal Study of Aging in Women

Scientific title

A 15-year longitudinal study investigating the role of environmental, anatomical, physiological, metabolic and genetic factors on health outcomes in older women.

Secondary ID [1]

Nil known

Universal Trial Number (UTN)

Trial acronym

PLSAW

Linked study record

Health condition

Health condition(s) or problem(s) studied:

Musculoskeletal

Cardiovascular

Cognitive

Condition category

Condition code

Musculoskeletal

Osteoporosis

Cardiovascular

Diseases of the vasculature and circulation including the lymphatic system

Neurological

Dementias

Intervention/exposure

Study type

Observational

Patient registry

False

Target follow-up duration

Target follow-up type

Description of intervention(s) / exposure

Baseline and longitudinal measurements of phenotypic data related to the health of older women including environmental factors (e.g. dietary intakes, physical activity), anatomical measures (e.g. bone mass and structure, anthropometry, body composition, carotid intimal medial thickness), physiological function (e.g. mobility, muscle strength), metabolic function (e.g. ApoE levels, hormonal status, homocysteine, beta-amyloid), and genetic polymorphisms (e.g. estrogen receptor, TGF beta, ApoE 4, Cyp19, MTHFR). The duration of observation was from 1998 to 2013. All participants were initially recruited in 1998 to a 5-year randomised controlled trial, the Calcium Intake Fracture Outcome Study (trial ID ACTRN12615000750583). Participants were then enrolled for an additional 10-year follow-up study (2003-2013).

Intervention code [1]

Not applicable

Comparator / control treatment

No control group

Control group

Uncontrolled

Outcomes

Primary outcome [1]

Fracture-related events assessed by self-reported events and data linkage to hospital admission/discharge records.

Timepoint [1]

Data linkage to hospital admission/discharge records is available for each participant from their baseline visit until their date of death or 15 years post baseline visit.

Primary outcome [2]

Cardiovascular events assessed by data linkage to hospital admission/discharge and mortality records.

Timepoint [2]

Data linkage to hospital admission/discharge and mortality records is available for each participant from their baseline visit until their date of death or 15 years post baseline visit.

Primary outcome [3]

Neurocognitive function assessed by Abbreviated Mini Mental Score, California Verbal Learning Test, CAMCOG, and the Mini Mental State Exam.

Timepoint [3]

Abbreviated Mini Mental State Score was assessed at baseline, 5, 7, 10 and 12 years. The California Verbal Learning Test and CAMCOG was assessed at 3 and 4 years. The Mini Mental State Exam was assessed at 3, 4, 10 and 12 years.

Secondary outcome [1]

Cancer-related events assessed by data linkage to hospital admission/discharge and mortality records.

Timepoint [1]

Data linkage to hospital admission/discharge records is available for each participant from their baseline visit until their date of death or 15 years post baseline visit.

Secondary outcome [2]

Renal disease-related events assessed by data linkage to hospital admission/discharge and mortality records.

Timepoint [2]

Data linkage to hospital admission/discharge records is available for each participant from their baseline visit until their date of death or 15 years post baseline visit.

Eligibility

Key inclusion criteria

The key inclusion criteria was age greater than 70 years and less than or equal to 85 years, and likelihood to survive a 5-year study. This key inclusion criteria was for all participants previously enrolled in the Calcium Intake Fracture Outcome Study (trial ID ACTRN12615000750583).

Minimum age

70 Years

Maximum age

85 Years

Sex

Females

Can healthy volunteers participate?

Yes

Key exclusion criteria

Receipt of a bone active agent. This exclusion criteria was for all participants previously enrolled in the Calcium Intake Fracture Outcome Study (trial ID ACTRN12615000750583).

There were no other specific exclusions so that the results could be generalized to the entire ambulant population.

Study design

Purpose

Natural history

Duration

Longitudinal

Selection

Random sample

Timing

Prospective

Statistical methods / analysis

Recruitment

Recruitment status

Completed

Date of first participant enrolment

Anticipated

Actual

2/02/1998

Date of last participant enrolment

Anticipated

Actual

21/12/1998

Date of last data collection

Anticipated

Actual

31/12/2013

Sample size

Target

1500

Accrual to date

Final

1500

Recruitment in Australia

Recruitment state(s)

Funding & Sponsors

Funding source category [1]

Government body

Name [1]

National Health and Medical Research Council of Australia

Address [1]

GHD Building Level 1, 16 Marcus Clarke Street, Canberra ACT 2601

Country [1]

Australia

Funding source category [2]

Government body

Name [2]

Healthway

Address [2]

PO Box 1284, West Perth WA 6872

Country [2]

Australia

Primary sponsor type

University

Name

University of Western Australia

Address

35 Stirling Hwy Crawley, WA Australia 6009

Country

Australia

Secondary sponsor category [1]

None

Name [1]

Address [1]

Country [1]

Ethics approval

Ethics application status

Approved

Ethics committee name [1]

The Human Rights Committee of the University of Western Australia, Perth, Australia

Ethics committee address [1]

35 Stirling Hwy Crawley, WA, Australia 6009

Ethics committee country [1]

Australia

Date submitted for ethics approval [1]

Approval date [1]

28/11/1997

Ethics approval number [1]

05/06/004/H50

Summary

Brief summary

The aim of this 15-year follow-up study was to determine the influence of environmental, anatomical, metabolic, physiological and genetic determinants on health outcomes in older women. This was a follow-up study of 1500 women aged 70 years and over, recruited from the general population of Perth, Western Australia.

Trial website

http://www.lsaw.com.au/

Trial related presentations / publications

Reconsideration of the Effects of Age on Proximal Femur Structure: Implications for Joint Replacement and Hip Fracture. Khoo BC, Brown JK, Prince RL. PLoS One. 2016 Oct 24;11(10):e0164949. doi: 10.1371/journal.pone.0164949.

Dietary fat composition, total body fat and regional body fat distribution in two Caucasian populations of middle-aged and older adult women. Muka T, Blekkenhorst LC, Lewis JR, Prince RL, Erler NS, Hofman A, Franco OH, Rivadeneira F, Kiefte-de Jong JC. Clin Nutr. 2016 Sep 28. doi: 10.1016/j.clnu.2016.09.018.

Comparison of flavonoid intake assessment methods. Ivey KL, Croft K, Prince RL, Hodgson JM. Food Funct. 2016 Sep 14;7(9):3748-59. doi: 10.1039/c4fo00234b.

Apple intake is inversely associated with all-cause and disease-specific mortality in elderly women. Hodgson JM, Prince RL, Woodman RJ, Bondonno CP, Ivey KL, Bondonno N, Rimm EB, Ward NC, Croft KD, Lewis JR. Br J Nutr. 2016 Mar 14;115(5):860-7. doi: 10.1017/S0007114515005231.

Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study. Bondonno NP, Lewis JR, Prince RL, Lim WH, Wong G, Schousboe JT, Woodman RJ, Kiel DP, Bondonno CP, Ward NC, Croft KD, Hodgson JM. Nutrients. 2016 Mar 10;8(3):159. doi: 10.3390/nu8030159.

Identification of IDUA and WNT16 Phosphorylation-Related Non-Synonymous Polymorphisms for Bone Mineral Density in Meta-Analyses of Genome-Wide Association Studies. Niu T, Liu N, Yu X, Zhao M, Choi HJ, Leo PJ, Brown MA, Zhang L, Pei YF, Shen H, He H, Fu X, Lu S, Chen XD, Tan LJ, Yang TL, Guo Y, Cho NH, Shen J, Guo YF, Nicholson GC, Prince RL, Eisman JA, Jones G, Sambrook PN, Tian Q, Zhu XZ, Papasian CJ, Duncan EL, Uitterlinden AG, Shin CS, Xiang S, Deng HW. J Bone Miner Res. 2016 Feb;31(2):358-68. doi: 10.1002/jbmr.2687.

Evaluation of a simplified hip structure analysis method for the prediction of incident hip fracture events. Khoo BC, Lewis JR, Brown K, Prince RL. Osteoporos Int. 2016 Jan;27(1):241-8. doi: 10.1007/s00198-015-3282-z.

Abdominal Aortic Calcification Identified on Lateral Spine Images From Bone Densitometers Are a Marker of Generalized Atherosclerosis in Elderly Women. Lewis JR, Schousboe JT, Lim WH, Wong G, Zhu K, Lim EM, Wilson KE, Thompson PL, Kiel DP, Prince RL. Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):166-73. doi: 10.1161/ATVBAHA.115.306383.

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.    Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, Nielson CM, Walter K, Pettersson-Kymmer U, McCarthy S, Eriksson J, Kwan T, Jhamai M, Trajanoska K, Memari Y, Min J, Huang J, Danecek P, Wilmot B, Li R, Chou WC, Mokry LE, Moayyeri A, Claussnitzer M, Cheng CH, Cheung W, Medina-Gómez C, Ge B, Chen SH, Choi K, Oei L, Fraser J, Kraaij R, Hibbs MA, Gregson CL, Paquette D, Hofman A, Wibom C, Tranah GJ, Marshall M, Gardiner BB, Cremin K, Auer P, Hsu L, Ring S, Tung JY, Thorleifsson G, Enneman AW, van Schoor NM, de Groot LC, van der Velde N, Melin B, Kemp JP, Christiansen C, Sayers A, Zhou Y, Calderari S, van Rooij J, Carlson C, Peters U, Berlivet S, Dostie J, Uitterlinden AG, Williams SR, Farber C, Grinberg D, LaCroix AZ, Haessler J, Chasman DI, Giulianini F, Rose LM, Ridker PM, Eisman JA, Nguyen TV, Center JR, Nogues X, Garcia-Giralt N, Launer LL, Gudnason V, Mellström D, Vandenput L, Amin N, van Duijn CM, Karlsson MK, Ljunggren Ö, Svensson O, Hallmans G, Rousseau F, Giroux S, Bussière J, Arp PP, Koromani F, Prince RL, Lewis JR, Langdahl BL, Pernille Hermann A, Jensen JB, Kaptoge S, Khaw KT, Reeve J, Formosa MM, Xuereb-Anastasi A, Åkesson K, McGuigan FE, Garg G, Olmos JM, Zarrabeitia MT, Riancho JA, Ralston SH, Alonso N, Jiang X, Goltzman D, Pastinen T, Grundberg E, Gauguier D, Orwoll ES, Karasik D, Davey-Smith G; AOGC Consortium, Smith AV, Siggeirsdottir K, Harris TB, Carola Zillikens M, van Meurs JB, Thorsteinsdottir U, Maurano MT, Timpson NJ, Soranzo N, Durbin R, Wilson SG, Ntzani EE, Brown MA, Stefansson K, Hinds DA, Spector T, Adrienne Cupples L, Ohlsson C, Greenwood CM; UK10K Consortium, Jackson RD, Rowe DW, Loomis CA, Evans DM, Ackert-Bicknell CL, Joyner AL, Duncan EL, Kiel DP, Rivadeneira F, Richards JB. Nature. 2015 Sep 14. doi: 10.1038/nature14878. [Epub ahead of print]

Evaluation of a simplified hip structure analysis method for the prediction of incident hip fracture events. Khoo BC, Lewis JR, Brown K, Prince RL. Osteoporos Int. 2015 Aug 18. [Epub ahead of print]

Tea and flavonoid intake predict osteoporotic fracture risk in elderly Australian women: a prospective study. Myers G, Prince RL, Kerr DA, Devine A, Woodman RJ, Lewis JR, Hodgson JM. Am J Clin Nutr. 2015 Aug 12. pii: ajcn109892. [Epub ahead of print]

Identification of IDUA and WNT16 Phosphorylation-Related Non-Synonymous Polymorphisms for Bone Mineral Density in Meta-Analyses of Genome-Wide Association Studies. Niu T, Liu N, Yu X, Zhao M, Choi HJ, Leo PJ, Brown MA, Zhang L, Pei YF, Shen H, He H, Fu X, Lu S, Chen XD, Tan LJ, Yang TL, Guo Y, Cho NH, Shen J, Guo YF, Nicholson GC, Prince RL, Eisman JA, Jones G, Sambrook PN, Tian Q, Zhu XZ, Papasian CJ, Duncan EL, Uitterlinden AG, Shin CS, Xiang S, Deng HW.J Bone Miner Res. 2015 Aug 8. doi: 10.1002/jbmr.2687. [Epub ahead of print]

Elevated Circulating Osteoprotegerin and Renal Dysfunction Predict 15-Year Cardiovascular and All-Cause Mortality: A Prospective Study of Elderly Women. Lewis JR, Lim WH, Ueland T, Wong G, Zhu K, Lim EM, Bollerslev J, Prince RL. PLoS One. 2015 Jul 29;10(7):e0134266. doi: 10.1371/journal.pone.0134266. eCollection 2015.

Effect of vitamin D supplementation alone or with calcium on adiposity measures: a systematic review and meta-analysis of randomized controlled trials. Chandler PD, Wang L, Zhang X, Sesso HD, Moorthy MV, Obi O, Lewis J, Prince RL, Danik JS, Manson JE, LeBoff MS, Song Y. Nutr Rev. 2015 Sep;73(9):577-93. doi: 10.1093/nutrit/nuv012. Epub 2015 Jul 14.

Dietary saturated fat intake and atherosclerotic vascular disease mortality in elderly women: a prospective cohort study. Blekkenhorst LC, Prince RL, Hodgson JM, Lim WH, Zhu K, Devine A, Thompson PL, Lewis JR. Am J Clin Nutr. 2015 Jun;101(6):1263-8. doi: 10.3945/ajcn.114.102392. Epub 2015 May 6.

Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies. Niu T, Liu N, Zhao M, Xie G, Zhang L, Li J, Pei YF, Shen H, Fu X, He H, Lu S, Chen XD, Tan LJ, Yang TL, Guo Y, Leo PJ, Duncan EL, Shen J, Guo YF, Nicholson GC, Prince RL, Eisman JA, Jones G, Sambrook PN, Hu X, Das PM, Tian Q, Zhu XZ, Papasian CJ, Brown MA, Uitterlinden AG, Wang YP, Xiang S, Deng HW. Hum Mol Genet. 2015 Aug 15;24(16):4710-27. doi: 10.1093/hmg/ddv144. Epub 2015 May 4.

Circulating Lipocalin 2 Levels Predict Fracture-Related Hospitalizations in Elderly Women: A Prospective Cohort Study. Lim WH, Wong G, Lim EM, Byrnes E, Zhu K, Devine A, Pavlos NJ, Prince RL, Lewis JR. J Bone Miner Res. 2015 May 1. doi: 1002/jbmr.2546. [Epub ahead of print]

Flavonoid intake and all-cause mortality. Ivey KL, Hodgson JM, Croft KD, Lewis JR, Prince RL. Am J Clin Nutr. 2015 May;101(5):1012-20. doi: 10.3945/ajcn.113.073106. Epub 2015 Apr 1.

Plasma neutrophil gelatinase-associated lipocalin and kidney function decline and kidney disease-related clinical events in older women.  Lim WH, Lewis JR, Wong G, Teo R, Lim EM, Byrnes E, Prince RL. Am J Nephrol. 2015;41(2):156-64. doi: 10.1159/000380831. Epub 2015 Mar 25. 

New genetic loci link adipose and insulin biology to body fat distribution. Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Mateo Leach I, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stan?áková A, Ju Sung Y, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hillege HL, Holmen O, Hunt SC, Isaacs A, Ittermann T, James AL, Johansson I, Juliusdottir T, Kalafati IP, Kinnunen L, Koenig W, Kooner IK, Kratzer W, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Mach F, Magnusson PK, Mahajan A, McArdle WL, Menni C, Merger S, Mihailov E, Milani L, Mills R, Moayyeri A, Monda KL, Mooijaart SP, Mühleisen TW, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nalls MA, Narisu N, Glorioso N, Nolte IM, Olden M, Rayner NW, Renstrom F, Ried JS, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Sennblad B, Seufferlein T, Sitlani CM, Vernon Smith A, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tayo BO, Thorand B, Thorleifsson G, Tomaschitz A, Troffa C, van Oort FV, Verweij N, Vonk JM, Waite LL, Wennauer R, Wilsgaard T, Wojczynski MK, Wong A, Zhang Q, Hua Zhao J, Brennan EP, Choi M, Eriksson P, Folkersen L, Franco-Cereceda A, Gharavi AG, Hedman ÅK, Hivert MF, Huang J, Kanoni S, Karpe F, Keildson S, Kiryluk K, Liang L, Lifton RP, Ma B, McKnight AJ, McPherson R, Metspalu A, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Olsson C, Perry JR, Reinmaa E, Salem RM, Sandholm N, Schadt EE, Scott RA, Stolk L, Vallejo EE, Westra HJ, Zondervan KT; ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium, Amouyel P, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J, Brown MJ, Burnier M, Campbell H, Chakravarti A, Chines PS, Claudi-Boehm S, Collins FS, Crawford DC, Danesh J, de Faire U, de Geus EJ, Dörr M, Erbel R, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gieger C, Gudnason V, Haiman CA, Harris TB, Hattersley AT, Heliövaara M, Hicks AA, Hingorani AD, Hoffmann W, Hofman A, Homuth G, Humphries SE, Hyppönen E, Illig T, Jarvelin MR, Johansen B, Jousilahti P, Jula AM, Kaprio J, Kee F, Keinanen-Kiukaanniemi SM, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Musk AW, Möhlenkamp S, Morris AD, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Palmer LJ, Penninx BW, Peters A, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Shuldiner AR, Staessen JA, Steinthorsdottir V, Stolk RP, Strauch K, Tönjes A, Tremblay A, Tremoli E, Vohl MC, Völker U, Vollenweider P, Wilson JF, Witteman JC, Adair LS, Bochud M, Boehm BO, Bornstein SR, Bouchard C, Cauchi S, Caulfield MJ, Chambers JC, Chasman DI, Cooper RS, Dedoussis G, Ferrucci L, Froguel P, Grabe HJ, Hamsten A, Hui J, Hveem K, Jöckel KH, Kivimaki M, Kuh D, Laakso M, Liu Y, März W, Munroe PB, Njølstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, Pérusse L, Peters U, Power C, Quertermous T, Rauramaa R, Rivadeneira F, Saaristo TE, Saleheen D, Sinisalo J, Slagboom PE, Snieder H, Spector TD, Thorsteinsdottir U, Stumvoll M, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Veronesi G, Walker M, Wareham NJ, Watkins H, Wichmann HE, Abecasis GR, Assimes TL, Berndt SI, Boehnke M, Borecki IB, Deloukas P, Franke L, Frayling TM, Groop LC, Hunter DJ, Kaplan RC, O'Connell JR, Qi L, Schlessinger D, Strachan DP, Stefansson K, van Duijn CM, Willer CJ, Visscher PM, Yang J, Hirschhorn JN, Zillikens MC, McCarthy MI, Speliotes EK, North KE, Fox CS, Barroso I, Franks PW, Ingelsson E, Heid IM, Loos RJ, Cupples LA, Morris AP, Lindgren CM, Mohlke KL. Nature. 2015 Feb 12;518(7538):187-96. doi: 10.1038/nature14132.

Consumption of a whey protein-enriched diet may prevent hepatic steatosis associated with weight gain in elderly women. Ooi EM, Adams LA, Zhu K, Lewis JR, Kerr DA, Meng X, Solah V, Devine A, Binns CW, Prince RL. Nutr Metab Cardiovasc Dis. 2015 Apr;25(4):388-95. doi: 10.1016/j.numecd.2014.11.005. Epub 2014 Nov 28.

Lifestyle and osteoporosis. Zhu K, Prince RL. Curr Osteoporos Rep. 2015 Feb;13(1):52-9. doi: 10.1007/s11914-014-0248-6.

The effect of yoghurt and its probiotics on blood pressure and serum lipid profile; a randomised controlled trial. Ivey KL, Hodgson JM, Kerr DA, Thompson PL, Stojceski B, Prince RL. Nutr Metab Cardiovasc Dis. 2015 Jan;25(1):46-51. doi: 10.1016/j.numecd.2014.07.012. Epub 2014 Aug 1.

The effects of calcium supplementation on verified coronary heart disease hospitalization and death in postmenopausal women: a collaborative meta-analysis of randomized controlled trials. Lewis JR, Radavelli-Bagatini S, Rejnmark L, Chen JS, Simpson JM, Lappe JM, Mosekilde L, PrenticeRL, Prince RL. J Bone Miner Res. 2015 Jan;30(1):165-75. doi: 10.1002/jbmr.2311. Review.

Consumption of a whey protein-enriched diet may prevent hepatic steatosis associated with weight gain in elderly women. Ooi EM, Adams LA, Zhu K, Lewis JR, Kerr DA, Meng X, Solah V, Devine A, Binns CW, Prince RL.Nutr Metab Cardiovasc Dis. 2014 Nov 28.

Comparison of estimated glomerular filtration rate by the chronic kidney disease epidemiology collaboration (CKD-EPI) equations with and without Cystatin C for predicting clinical outcomes in elderly women. Lim WH, Lewis JR, Wong G, Turner RM, Lim EM, Thompson PL, Prince RL.PLoS One. 2014 Sep 29;9(9)

The effect of yoghurt and its probiotics on blood pressure and serum lipid profile; a randomised controlled trial. Ivey KL, Hodgson JM, Kerr DA, Thompson PL, Stojceski B, Prince RL.Nutr Metab Cardiovasc Dis. 2015 Jan;25(1):46-51.

Influence of ARHGEF3 and RHOA knockdown on ACTA2 and other genes in osteoblasts and osteoclasts. Mullin BH, Mamotte C, Prince RL, Wilson SG. PLoS One. 2014 May 19;9(5)

Long-term proton pump inhibitor therapy and falls and fractures in elderly women: a prospective cohort study. Lewis JR, Barre D, Zhu K, Ivey KL, Lim EM, Hughes J, Prince RL. J Bone Miner Res. 2014 Nov;29(11):2489-97

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, Alonso N, Husted LB, Valero C, Hernandez JL, Lewis JR, Kaptoge SK, Zhu K, Cupples LA, Medina-Gómez C, Vandenput L, Kim GS, Hun Lee S, Castaño-Betancourt MC, Oei EH, Martinez J, Daroszewska A, van der Klift M, Mellström D, Herrera L, Karlsson MK, Hofman A, Ljunggren Ö, Pols HA, Stolk L, van Meurs JB, Ioannidis JP, Zillikens MC, Lips P, Karasik D, Uitterlinden AG, Styrkarsdottir U, Brown MA, Koh JM, Richards JB, Reeve J, Ohlsson C, Ralston SH, Kiel DP, Rivadeneira F. Bone. 2014 Feb;59:20-7.

Elevated osteoprotegerin predicts declining renal function in elderly women: a 10-year prospective cohort study. Lewis JR, Lim WH, Zhu K, Wong G, Dhaliwal SS, Lim EM, Ueland T, Bollerslev J, Prince RL. Am J Nephrol. 2014;39(1):66-74.

Dairy food intake, peripheral bone structure, and muscle mass in elderly ambulatory women. Radavelli-Bagatini S, Zhu K, Lewis JR, Prince RL. J Bone Miner Res. 2014 Jul;29(7)

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Moayyeri A, Hsu YH, Karasik D, Estrada K, Xiao SM, Nielson C, Srikanth P, Giroux S, Wilson SG, Zheng HF, Smith AV, Pye SR, Leo PJ, Teumer A, Hwang JY, Ohlsson C, McGuigan F, Minster RL, Hayward C, Olmos JM, Lyytikäinen LP, Lewis JR, Swart KM, Masi L, Oldmeadow C, Holliday EG, Cheng S, van Schoor NM, Harvey NC, Kruk M, del Greco M F, Igl W, Trummer O, Grigoriou E, Luben R, Liu CT, Zhou Y, Oei L, Medina-Gomez C, Zmuda J, Tranah G, Brown SJ, Williams FM, Soranzo N, Jakobsdottir J, Siggeirsdottir K, Holliday KL, Hannemann A, Go MJ, Garcia M, Polasek O, Laaksonen M, Zhu K, Enneman AW, McEvoy M, Peel R, Sham PC, Jaworski M, Johansson Å, Hicks AA, Pludowski P, Scott R, Dhonukshe-Rutten RA, van der Velde N, Kähönen M, Viikari JS, Sievänen H, Raitakari OT, González-Macías J, Hernández JL, Mellström D, Ljunggren O, Cho YS, Völker U, Nauck M, Homuth G, Völzke H, Haring R, Brown MA, McCloskey E, Nicholson GC, Eastell R, Eisman JA, Jones G, Reid IR, Dennison EM, Wark J, Boonen S, Vanderschueren D, Wu FC, Aspelund T, Richards JB, Bauer D, Hofman A, Khaw KT, Dedoussis G, Obermayer-Pietsch B, Gyllensten U, Pramstaller PP, Lorenc RS, Cooper C, Kung AW, Lips P, Alen M, Attia J, Brandi ML, de Groot LC, Lehtimäki T, Riancho JA, Campbell H, Liu Y, Harris TB, Akesson K, Karlsson M, Lee JY, Wallaschofski H, Duncan EL, O'Neill TW, Gudnason V, Spector TD, Rousseau F, Orwoll E, Cummings SR, Wareham NJ, Rivadeneira F, Uitterlinden AG, Prince RL, Kiel DP, Reeve J, Kaptoge SK. Hum Mol Genet. 2014 Jun 1;23(11):3054-68.A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT, Alonso N, Kaptoge SK, Thorleifsson G, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Kruk M, Lewis JR, Patel MS, Scollen S, Svensson O, Trompet S, van Schoor NM, Zhu K, Buckley BM, Cooper C, Ford I, Goltzman D, González-Macías J, Langdahl BL, Leslie WD, Lips P, Lorenc RS, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Slagboom PE, Garcia-Ibarbia C, Ingvarsson T, Johannsdottir H, Luben R, Medina-Gómez C, Arp P, Nandakumar K, Palsson ST, Sigurdsson G, van Meurs JB, Zhou Y, Hofman A, Jukema JW, Pols HA, Prince RL, Cupples LA, Marshall CR, Pinto D, Sato D, Scherer SW, Reeve J, Thorsteinsdottir U, Karasik D, Richards JB, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F, Estrada K. J Med Genet. 2014 Feb;51(2):122-31.

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. Zhang L, Choi HJ, Estrada K, Leo PJ, Li J, Pei YF, Zhang Y, Lin Y, Shen H, Liu YZ, Liu Y, Zhao Y, Zhang JG, Tian Q, Wang YP, Han Y, Ran S, Hai R, Zhu XZ, Wu S, Yan H, Liu X, Yang TL, Guo Y, Zhang F, Guo YF, Chen Y, Chen X, Tan L, Zhang L, Deng FY, Deng H, Rivadeneira F, Duncan EL, Lee JY, Han BG, Cho NH, Nicholson GC, McCloskey E, Eastell R, Prince RL, Eisman JA, Jones G, Reid IR, Sambrook PN, Dennison EM, Danoy P, Yerges-Armstrong LM, Streeten EA, Hu T, Xiang S, Papasian CJ, Brown MA, Shin CS, Uitterlinden AG, Deng HW. Hum Mol Genet. 2014 Apr 1;23(7)

The effects of 3 years of calcium supplementation on common carotid artery intimal medial thickness and carotid atherosclerosis in older women: an ancillary study of the CAIFOS randomized controlled trial. Lewis JR, Zhu K, Thompson PL, Prince RL. J Bone Miner Res. 2014 Mar;29(3):534-41.

Effects of the assessment of 4 determinants of structural geometry on QCT- and DXA-derived hip structural analysis measurements in elderly women. Khoo BC, Brown K, Zhu K, Price RI, Prince RL. J Clin Densitom. 2014 Jan-Mar;17(1):38-46

A predictive model for knee joint replacement in older women. Lewis JR, Dhaliwal SS, Zhu K, Prince RL. PLoS ONE 2013;8:

Associations of proanthocyanidin intake with renal function and clinical outcomes in elderly women. Ivey KL, Lewis JR, Lim WH, Lim EM, Hodgson JM, Prince RL PLoS ONE 2013;8:e71166.

Association of dairy intake with body composition and physical function in older community-dwelling women. Radavelli-Bagatini S, Zhu K, Lewis JR, Dhaliwal SS, Prince RL. Journal of the Academy of Nutrition and Dietetics 2013;113:1669-74.

Tea and non-tea flavonol intakes in relation to atherosclerotic vascular disease mortality in older women. Ivey KL, Lewis JR, Prince RL, Hodgson JM. The British journal of nutrition 2013;110:1648-55.]

Effects of the Assessment of 4 Determinants of Structural Geometry on QCT- and DXA-Derived Hip Structural Analysis Measurements in Elderly Women. Khoo BC, Brown K, Zhu K, Price RI, Prince RL. Journal of Clinical Densitometry : 2014;17:38

Five-year decline in estimated glomerular filtration rate associated with a higher risk of renal disease and atherosclerotic vascular disease clinical events in elderly women. Lim WH, Lewis JR, Wong G, et al. QJM : 2013;106:443-50.

Elevated osteoprotegerin predicts declining renal function in elderly women: a 10-year prospective cohort study. Lewis JR, Lim WH, Zhu K, Wong G, Dhaliwal SS, Lim EM, Ueland T, Bollerslev J, Prince RL. Am J Nephrol. 2014;39(1):66-74

Glutamine repeat variants in human RUNX2 associated with decreased femoral neck BMD, broadband ultrasound attenuation and target gene transactivation. Morrison NA, Stephens AA, Osato M, Polly P, Tan TC, Yamashita N, Doecke JD, Pasco J, Fozzard N, Jones G, Ralston SH, Sambrook

Estimated glomerular filtration rate as an independent predictor of atherosclerotic vascular disease in older women. Lewis JR, Lim W, Dhaliwal SS, Zhu K, Lim EM, Thompson PL, Prince RL. BMC Nephrol. 2012 Jul 16;13:58.

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. Zheng HF, Tobias JH, Duncan E, Evans DM, Eriksson J, Paternoster L et al. PLoS Genet. 2012 Jul;8(7):e1002745.

Assessment of gene-by-sex interaction effect on bone mineral density. Liu CT, Estrada K, Yerges-Armstrong LM, Amin N, Evangelou E, Li G, et  al. J Bone Miner Res. 2012 Oct;27(10):2051-64. 

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL et al.  Nat Genet. 2012 Apr 15;44(5):491-501.

Adverse events from calcium supplementation: relationship to errors in myocardial infarction self-reporting in randomized controlled trials of calcium supplementation. Lewis JR, Zhu K, Prince RL.   J Bone Miner Res.  2012 Mar;27(3):719-22. 

An in vivo comparison of hip structure analysis (HSA) with measurements obtained by QCT. Ramamurthi K, Ahmad O, Engelke K, Taylor RH, Zhu K, Gustafsson S, et al. Osteoporos Int. 2012 23:543–551  

Differences in structural geometrical outcomes at the neck of the proximal femur using two-dimensional DXA-derived projection (APEX) and three-dimensional QCT-derived (BIT QCT) techniques. Khoo BC, Brown K, Zhu K, Pollock M, Wilson KE, Price RL, et al. Osteoporos Int. 2012 23:1393–1398. 

The calcium scare: response to Bolland et al. Nordin BE, Lewis JR, Daly RM, Prince RL. Osteoporos Int. 2011 Dec;22(12):3081–3.   

Association between yogurt, milk, and cheese consumption and common carotid artery intima-media thickness and cardiovascular disease risk factors in elderly women. Ivey KL, Lewis JR, Hodgson JM, Zhu K, Dhaliwal SS, Thompson PL, et al.   Am J Clin Nutr. 2011 Jul;94(1):234-9.   

Calcium supplementation and the risks of atherosclerotic vascular disease in older women: results of a 5-year RCT and a 4.5-year follow-up.Lewis JR, Calver J, Zhu K, Flicker L, Prince RL J Bone Miner Res. 2011 Jan;26(1):35-41. 

Significant association between common polymorphisms in the aromatase gene CYP19A1 and bone mineral density in postmenopausal women. Mullin BH, Carter KW, Lewis JR, Ingley E, Wilson SG, Prince RL.Calcif Tissue Int. 2011 Dec;89(6):464-71.  

'Timed up and go' test and bone mineral density measurement for fracture prediction. Zhu K, Devine A, Lewis JR, Dhaliwal SS, Prince RL. Arch Intern Med. 2011 Oct 10;171(18):1655-61.  

A non-synonymous coding change in the CYP19A1 gene Arg264Cys (rs700519) does not affect circulating estradiol, bone structure or fracture. Wang JZ, Deogan MS, Lewis JR, Chew S, Mullin BH, McNab TJ, et al.  BMC Med Genet. 2011 Dec 20;12(1):165.  

Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women. Chew S, Mullin BH, Lewis JR, Spector TD, Prince RL, Wilson SG. Osteoporos Int. 2011 Jun;22(6):1981-6.    

Reply to "Calcium supplements and cardiovascular risk". Lewis JR, Calver J, Zhu K, Flicker L, Prince RL. J Bone Miner Res:epub2011/01/06   

Evidence of harm is unconvincing.Prince RL, Zhu K, Lewis JR.  BMJ. 2011;342:d3541.  Adequacy and change in nutrient and food intakes with aging in a seven-year cohort study in elderly women. Zhu K, Devine A, Suleska A, Tan CY, Toh CZ, Kerr D, Prince RL. J Nutr Health Aging 2010 14(9):723-9. 

Habitual chocolate intake and vascular disease: a prospective study of clinical outcomes in older women.Lewis JR, Prince RL, Zhu K, Devine A, Thompson PL, Hodgson JM.  Arch Intern Med. 2010 170(20):1857-8. 

Volumetric DXA (VXA) - a new method to extract 3D information from multiple in vivo DXA images. Ahmad O, Ramamurthi K, Wilson KE, Engelke K, Prince RL, Taylor RH.  J Bone Miner Res. 2010 25:2468-75.  

The effects of high potassium consumption on bone mineral density in a prospective cohort study of elderly postmenopausal women.Zhu K, Devine A, Prince RL. Osteoporos Int. 2009 20(2):335-40.  

The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly women. Zhu K, Beilby J, Dick IM, Devine A, Soos M, Prince RL. Osteoporos Int.  2009 20(7):1183-91.  

A cohort study of the effects of serum OPG and OPG gene polymorphisms on cardiovascular mortality in elderly women.Ueland T, Wilson SG, Amirul Islam FM, Mullin B, Devine A, Bollerslev J, Zhu K, Prince RL. Clin Endocrinol (Oxf). 2009 17(6):828-833.  

Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Timpson NJ, Tobias JH, Richards JB, Soranzo N, Duncan EL, Sims AM, Whittaker P, Kumanduri V, Zhai G, Glaser B, Eisman J, Jones G, Nicholson G, Prince R, Seeman E, Spector T, Brown MA, Peltonen L, Smith GD, Deloukas P, Evans DM. Hum Mol Genet. 2009 18(8):1510-7.  

A 5-Year Cohort Study of the Effects of High Protein Intake on Lean Mass and Bone Mineral Content in Elderly Postmenopausal Women.Meng X, Zhu K, Devine A, Kerr DA, Binns CW, Prince RL.  J Bone Miner Res. 2009  

Comparison of QCT-derived and DXA-derived areal bone mineral density and T scores.Khoo BC, Brown K, Cann C, Zhu K, Henzell S, Low V, Gustafsson S, Price RI, Prince RL.  Osteoporos Int. 2009 20(9):1539-45. 

Effects of calcium and vitamin D supplementation on hip bone mineral density and calcium-related analytes in elderly ambulatory Australian women: a five-year randomized controlled trial. Zhu K, Devine A, Dick IM, Wilson SG, Prince RL. J Clin Endocrinol Metab 2008;93(3):743-9. 

Chocolate consumption and bone density in older women.Hodgson JM, Devine A, Burke V, Dick IM, Prince RL. Am J Clin Nutr 2008;87(1):175-80.  

Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis. .Mullin BH, Prince RL, Dick IM, Hart DJ, Spector TD, Dudbridge F, et al. Am J Hum Genet 2008;82(6):1262-9. 

Bone structural effects of variation in the TNFRSF1B gene encoding the tumor necrosis factor receptor 2. Mullin BH, Prince RL, Dick IM, Islam FM, Hart DJ, Spector TD, et al. Osteoporos Int 2008;19(7):961-8. 

Association of back pain frequency with mortality, coronary heart events, mobility, and quality of life in elderly women.Zhu K, Devine A, Dick IM, Prince RL.  Spine 2007;32:2012-8. 

The clinical utility of measured kyphosis as a predictor of the presence of vertebral deformities. Prince RL, Devine A, Dick IM. Osteoporos Int 2007;18:621-7. 

A cohort study of the effect of endogenous estrogen on spine fracture risk and bone structure in elderly women and an assessment of its diagnostic usefulness.Prince RL, Dick IM, Beilby J, Dhaliwal SS, Devine A.  Bone 2007;41:33-8. 

Geometric indices of bone strength are associated with physical activity and dietary calcium intake in healthy older women.Nurzenski MK, Briffa NK, Price RI, Khoo BC, Devine A, Beck TJ, Prince RL.  J Bone Miner Res 2007;22:416-24. 

No associations between OPG gene polymorphisms or serum levels and measures of osteoporosis in elderly Australian women. Ueland T, Bollerslev J, Wilson SG, Dick IM, Islam FM, Mullin BH, Devine A, Prince RL. Bone 2007;40:175-81.  

Tea drinking is associated with benefits on bone density in older women. Am J Clin Nutr 2007;86:1243-7.Devine A, Hodgson JM, Dick IM, Prince RL.  

Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women.Prince RL, Devine A, Dhaliwal SS, Dick IM.  Arch Intern Med 2006;166:869-75. 

Do sleep problems or urinary incontinence predict falls in elderly women? Teo JSH, Briffa K, Devine A, et al. Australian Journal of Physiotherapy 2006;52:19-24. 

Drinking tea is associated with lower plasma total homocysteine in older women.Hodgson JM, Devine A, Puddey IB, Beilby J, Prince RL.  Asia Pac J Clin Nutr 2006;15:253-8. 

Prediction of incident osteoporotic fractures in elderly women using the free estradiol index.Devine A, Dick IM, Dhaliwal SS, Naheed R, Beilby J, Prince RL.  Osteoporos Int 2005;16:216-221. 

Effects of endogenous estrogen on renal calcium and phosphate handling in elderly women. Dick IM, Devine A, Beilby J, Prince RL. Am J Physiol Endocrinol Metab 2005;288:E430-5. 

LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women.Bollerslev J, Wilson SG, Dick IM, Islam FM, Ueland T, Palmer L, Devine A, Prince RL. Bone 2005;36:599-606. 

Bone mass effects of a BMP4 gene polymorphism in postmenopausal women.Ramesh Babu L, Wilson SG, Dick IM, Islam FM, Devine A, Prince RL.  Bone 2005;36:555-61. 

Association of an aromatase TTTA repeat polymorphism with circulating estrogen, bone structure, and biochemistry in older women.Dick IM, Devine A, Prince RL.  Am J Physiol Endocrinol Metab 2005;288:E989-95. 

Klotho gene polymorphisms are associated with osteocalcin levels but not bone density of aged postmenopausal women. Mullin, BH, Wilson, SG, Islam, FMA, Dick, IM, Devine, A, Prince, RL. Calcif Tissue Int 2005;77:145-51.   

In vivo short-term precision of hip structure analysis variables in comparison with bone mineral density using paired dual-energy X-ray absorptiometry scans from multi-center clinical trials.  Khoo, BC, Beck, TJ, Qiao, QH, Parakh, P, Semanick, L, Prince, RL, Singer, KP, Price, RI.Bone 2005; 37: 112-121.   

Protein consumption is an important predictor of lower limb bone mass in elderly women.  Devine, A, Dick, IM, Islam, AFM, Dhaliwal, SS, Prince, RL. American Journal of Clinical Nutrition 2005; 81: 1423-1428.   

Calcium-Sensing Receptor Gene Polymorphism A986S Does Not Predict Serum Calcium Level, Bone Mineral Density, Calcaneal Ultrasound Indices, or Fracture Rate in a Large Cohort of Elderly Women.Bollerslev J, Wilson SG, Dick IM, Devine A, Dhaliwal SS, Prince RL. Calcif Tissue Int 2004;74(1):12-17.  

Phenolic acid metabolites as biomarkers for tea- and coffee- derived polyphenol exposure in human subjects. Hodgson JM, Chan SY, Puddey IB, Devine A, Wattanapenpaiboon N, Wahlqvist ML, et al. British Journal of Nutrition 2004;91(2):301-306.  

Physical Activity and Calcium Consumption Are Important Determinants of Lower Limb Bone Mass in Older Women',Devine, A., Dhaliwal, S.S., Dick, I.M., Bollerslev, J., Prince, R.L. Journal of Bone and Mineral Research  2004; 19: 1634-39.  

Expression of the HFE haemochromatosis gene in a community-based population of elderly females. Rossi JA, Kuek C, Beilby JP, Jeffrey GP, Devine A, L. PR. Journal of Gastroenterology and Hepatology 2004; 19:1150-54. 

Prevalence of lower extremity pain and its association with functionality and quality of life in elderly women in Australia.  Chen J, Devine A, Dick IM, Dhaliwal SS, Prince RL. Journal of Rheumatology.  2003;30(12):2689-93.  

Comparison of genome screens for two independent cohorts provides replication of suggestive linkage of bone mineral density to 3p21 and 1p36. Wilson SG, Reed PW, Bansal A, Chiano M, Lindersson M, Langdown M, et al. Am J Hum Genet 2003;72(1):144-55. 

Impact of the analysis of a bone density reference range on determination of the T-score. Price RI, Walters MJ, Retallack RW, Henderson NK, Kerr D, Henzell S, et al. J Clin Densitom 2003;6:51-62. 

Tea intake is inversely related to blood pressure in older women. Hodgson JM, Devine A, Puddey IB, Chan SY, Beilin LJ, Prince RL. J Nutr 2003;133(9):2883-86. 

Comparison of Pencil-Beam and Fan-Beam DXA Systems. Henzell S, Dhaliwal SS, Price RI, Gill F, Ventouras C, Green C, et al. J Clin Densitom 2003;6:205-10. 

The T869C TGF beta polymorphism is associated with fracture, bone mineral density, and calcaneal quantitative ultrasound in elderly women. Dick IM, Devine A, Li S, Dhaliwal SS, Prince RL. Bone 2003;33(3):335-41. 

Apolipoprotein E4 is associated with reduced calcaneal quantitative ultrasound measurements and bone mineral density in elderly women. Dick IM, Devine A, Marangou A, Dhaliwal SS, Laws S, Martins RN, et al. Bone 2002;31(4):497-502. 

Effects of vitamin D metabolites on intestinal calcium absorption and bone turnover in elderly women. Devine A, Wilson SG, Dick IM, Prince RL.Am J Clin Nutr 2002;75(2):283-8. 

Recreational physical activity levels in healthy older women: the importance of fear of falling. Bruce DG, Devine A, Prince RL. J Am Geriatr Soc 2002;50(1):84-9. 

Lifetime and five-year age-specific risks of first and subsequent osteoporotic fractures in postmenopausal women. Doherty DA, Sanders KM, Kotowicz MA, Prince RL. Osteoporos Int 2001;12(1):16-23. 

Effects of zinc and other nutritional factors on insulin-like growth factor I and insulin-like growth factor binding proteins in postmenopausal women. Devine A, Rosen C, Mohan S, Baylink D, Prince RL. Am J Clin Nutr 1998;68(1):200-6.

Public notes

Contacts

Principal investigator

Name

Prof Richard Prince

Address

The University of Western Australia
35 Stirling Highway
Crawley WA 6009
Perth, Australia

Country

Australia

Phone

+61 8 6151 0830

Fax

Richard.Prince@uwa.edu.au

Contact person for public queries

Name

Richard Prince

Address

The University of Western Australia
35 Stirling Highway
Crawley WA 6009
Perth, Australia

Country

Australia

Phone

+61 8 6151 0830

Fax

Richard.Prince@uwa.edu.au

Contact person for scientific queries

Name

Richard Prince

Address

The University of Western Australia
35 Stirling Highway
Crawley WA 6009
Perth, Australia

Country

Australia

Phone

+61 8 6151 0830

Fax

Richard.Prince@uwa.edu.au

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Source	Title	Year of Publication	DOI
Embase	Association of dietary nitrate with atherosclerotic vascular disease mortality: A prospective cohort study of older adult women.	2017	https://dx.doi.org/10.3945/ajcn.116.146761
Embase	Cruciferous and allium vegetable intakes are inversely associated with 15-Year atherosclerotic vascular disease deaths in older adult women.	2017	https://dx.doi.org/10.1161/JAHA.117.006558
Embase	Vegetable diversity, injurious falls, and fracture risk in older women: A prospective cohort study.	2018	https://dx.doi.org/10.3390/nu10081081
Embase	Vegetable diversity in relation with subclinical atherosclerosis and 15-year atherosclerotic vascular disease deaths in older adult women.	2020	https://dx.doi.org/10.1007/s00394-019-01902-z
Embase	Abdominal aortic calcification, cardiac troponin I and atherosclerotic vascular disease mortality in older women.	2022	https://dx.doi.org/10.1136/heartjnl-2021-319879
Embase	Cardiovascular disease, muscle function, and long-term falls risk: The Perth Longitudinal Study of Ageing Women.	2023	https://dx.doi.org/10.1016/j.archger.2022.104911

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