Trial Review

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Trial registered on ANZCTR


Registration number
ACTRN12615001306505
Ethics application status
Not required
Date submitted
9/11/2015
Date registered
30/11/2015
Date last updated
30/11/2015
Type of registration
Retrospectively registered

Titles & IDs
Public title
Are interventions to increase the uptake of cardiovascular risk factor screening effective? A systematic review and meta-analysis
Scientific title
Systematic review of interventions studies that had a comparator group (randomised controlled trials, controlled trials non-randomised, pre- and post studies) in adult population to increase the uptake of cardiovascular risk factor screening.
Secondary ID [1] 287840 0
None
Universal Trial Number (UTN)
NA
Trial acronym
METACVR-SCREEN

Meta-analysis of efficacy of interventions to increase the uptake of cardiovascular risk factors screening
Linked study record

Health condition
Health condition(s) or problem(s) studied:
uptake of cardiovascular risk factors screening 296726 0
Condition category
Condition code
Cardiovascular 296959 296959 0 0
Coronary heart disease
Public Health 296961 296961 0 0
Other public health
Cardiovascular 296962 296962 0 0
Hypertension

Intervention/exposure
Study type
Observational
Patient registry
False
Target follow-up duration
Target follow-up type
Description of intervention(s) / exposure
All types of interventions or strategies targeted either at individual, community, health care professional or health care system to increase participation of cardiovascular risk screening
Intervention code [1] 293224 0
Not applicable
Comparator / control treatment
usual care or an active intervention
Control group
Active

Outcomes
Primary outcome [1] 296570 0
The uptake of screening are measured in 1) participants’ attendance rate for risk screening or 2) screening rate or risk factors recording performed by health care providers.
Timepoint [1] 296570 0
at anytime after the intervention completed
Secondary outcome [1] 318771 0
none
Timepoint [1] 318771 0
none

Eligibility
Key inclusion criteria
Intervention studies that had a comparator group that were conducted in primary care practices or in the community.
Minimum age
18 Years
Maximum age
No limit
Sex
Both males and females
Can healthy volunteers participate?
Yes
Key exclusion criteria
Studies which looked at specific populations such as screening targeted at familial hypercholesterolaemia, people with mental disable or patients with rheumatoid arthritis , etc.

Study design
Purpose
Screening
Duration
Selection
Defined population
Timing
Both
Statistical methods / analysis
Data from relevant studies were pooled using random-effects model. Relative risk (RR) with 95% confidence interval (95%CI) were performed for all sets of comparisons. A test of heterogeneity with reported P-value was performed and the degree of inconsistency across studies was quantified using I2

Recruitment
Recruitment status
Completed
Date of first participant enrolment
Anticipated
Actual
12/06/2014
Date of last participant enrolment
Anticipated
Actual
15/08/2015
Date of last data collection
Anticipated
Actual
Sample size
Target
131943
Accrual to date
Final
131943
Recruitment in Australia
Recruitment state(s)
SA
Recruitment outside Australia
Country [1] 7314 0
Canada
State/province [1] 7314 0
Country [2] 7315 0
United Kingdom
State/province [2] 7315 0
Country [3] 7316 0
United States of America
State/province [3] 7316 0
Country [4] 7317 0
Netherlands
State/province [4] 7317 0
Country [5] 7318 0
New Zealand
State/province [5] 7318 0
Country [6] 7319 0
Denmark
State/province [6] 7319 0
Country [7] 7320 0
Sweden
State/province [7] 7320 0

Funding & Sponsors
Funding source category [1] 292356 0
University
Name [1] 292356 0
Postgraduate Research Grant (Project No: PG049-2014A), University of Malaya.
Country [1] 292356 0
Malaysia
Primary sponsor type
University
Name
University of Malaya
Address
Institut Pengurusan Penyelidikan & Perundingan,
University Malaya, Jalan Lembah Pantai, Wilayah Persekutuan, 50603 Kuala Lumpur, Malaysia
Country
Malaysia
Secondary sponsor category [1] 291037 0
None
Name [1] 291037 0
Address [1] 291037 0
Country [1] 291037 0

Ethics approval
Ethics application status
Not required

Summary
Brief summary
Cardiovascular disease (CVD) is the leading cause of death globally. However, many individuals are unaware of their CVD risk factors.
We systematically review the medical literature to determine the efficacy of existing intervention strategies to increase the uptake of cardiovascular risk factor screening. A systematic search was conducted through Pubmed, CINAHL, EMBASE and Cochrane Central Register of Controlled Trials. Additional articles were located through backward and forward citation search. The quality of studies was evaluated using Cochrane risk of bias assessment tool. Data were pooled using random-effects model..
Trial website
Trial related presentations / publications
Public notes

Contacts
Principal investigator
Name 61438 0
A/Prof Ai Theng Cheong
Address 61438 0
Department of Family Medicine
Faculty of Medicine and Health Sciences
Universiti Putra Malaysia
43400 Serdang Selangor
Country 61438 0
Malaysia
Phone 61438 0
+60389472538
Fax 61438 0
Email 61438 0
cheaitheng@upm.edu.my
Contact person for public queries
Name 61439 0
A/Prof Ai Theng Cheong
Address 61439 0
Department of Family Medicine
Faculty of Medicine and Health Sciences
Universiti Putra Malaysia
43400 Serdang Selangor
Country 61439 0
Malaysia
Phone 61439 0
+60389472538
Fax 61439 0
Email 61439 0
cheaitheng@upm.edu.my
Contact person for scientific queries
Name 61440 0
A/Prof Ai Theng Cheong
Address 61440 0
Department of Family Medicine
Faculty of Medicine and Health Sciences
Universiti Putra Malaysia
43400 Serdang Selangor
Country 61440 0
Malaysia
Phone 61440 0
+60389472538
Fax 61440 0
Email 61440 0
cheaitheng@upm.edu.my

No information has been provided regarding IPD availability


What supporting documents are/will be available?

No Supporting Document Provided



Results publications and other study-related documents

Documents added manually
No documents have been uploaded by study researchers.

Documents added automatically
No additional documents have been identified.