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Trial registered on ANZCTR

Registration number
Ethics application status
Date submitted
Date registered
Date last updated
Type of registration
Retrospectively registered

Titles & IDs
Public title
Comparison of visual quality achieved with the Rayner intraocular lenses
Scientific title
Comparison of postimplantation visual quality achieved with the Rayner aspheric intraocular lenses versus spherical lenses in patients who have undergone uneventful phacoemulsification and intraocular lens implantation surgery
Secondary ID [1] 281082 0
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
cataract 287236 0
Condition category
Condition code
Eye 287560 287560 0 0
Diseases / disorders of the eye

Study type
Description of intervention(s) / exposure
Patients were implanted with an aspheric intraocular lens (IOL) Rayner 920H in one eye and a spherical IOL Rayner 620H in the fellow eye. These lenses are intraocular, so participants will be wearing the lenses for wholelife. IOL implantation is a single session going for 30 minutes. The eye implanted with the aspheric IOL was chosen at random for each patient. Rayner IOLs are single piece lenses composed of foldable hydrophilic acrylic material (refractive index, 1.46) with an overall length of 12.5 mm and optic diameter of 6.25 mm.

Recruitment period of the study is 1 year.
Intervention code [1] 285536 0
Treatment: Devices
Comparator / control treatment
Two different types of same intraocular lens (IOL) were compared. Spherical Rayner IOL group was the control group.
Control group

Primary outcome [1] 287831 0
contrast sensitivity was assessed Hamilton-Veale contrast sensitivity test
Timepoint [1] 287831 0
at one month following surgery
Primary outcome [2] 287832 0
ocular wavefront higher order aberrations were assessed with the Schwind aberrometer
Timepoint [2] 287832 0
at one month following surgery
Secondary outcome [1] 298898 0
Timepoint [1] 298898 0

Key inclusion criteria
Patients who have undergone uneventfull phacoemulsification and IOL implantation surgery were included in the study
Minimum age
56 Years
Maximum age
85 Years
Both males and females
Can healthy volunteers participate?
Key exclusion criteria
Exclusion criteria included the presence of surgical complications or any ocular disease, such as corneal opacities or irregularity, amblyopia, anisometropia, glaucoma or retinal abnormalities

Study design
Purpose of the study
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Masking / blinding
Who is / are masked / blinded?

Intervention assignment
Other design features
Type of endpoint(s)
Statistical methods / analysis

Recruitment status
Date of first participant enrolment
Date of last participant enrolment
Date of last data collection
Sample size
Accrual to date
Recruitment outside Australia
Country [1] 4506 0
State/province [1] 4506 0

Funding & Sponsors
Funding source category [1] 285867 0
Self funded/Unfunded
Name [1] 285867 0
Address [1] 285867 0
Country [1] 285867 0
Primary sponsor type
Ramazan Yagci
Fatih University, Medical School
Alparslan Turkes C. No:57 06510 Emek/Ankara
Secondary sponsor category [1] 284689 0
Name [1] 284689 0
Address [1] 284689 0
Country [1] 284689 0

Ethics approval
Ethics application status

Brief summary
The goal of cataract surgery is no longer limited to the restoration of good visual acuity; most surgeons now aim to provide their patients with the best visual quality possible. The maximization of visual quality – objectively assessed via contrast sensitivity measurement or wavefront aberrometry – is a key focus of new aspheric intraocular lens designs. Aspheric IOLs produce fewer positive spherical corneal aberrations than conventional spherical IOLs, and as such, produce better contrast sensitivity and visual acuity.

In this study we aimed to compare the levels of ocular aberrations and contrast sensitivity achieved with implantation of the Rayner 920H aspheric aberration-neutral IOL and the Rayner 620H spherical acrylic IOL in patients undergoing bilateral cataract surgery.
Trial website
Trial related presentations / publications
Public notes

Principal investigator
Name 34611 0
Address 34611 0
Country 34611 0
Phone 34611 0
Fax 34611 0
Email 34611 0
Contact person for public queries
Name 17858 0
Ramazan Yagci
Address 17858 0
Fatih University, Medical School
Alparslan Turkes C. No:57 06510 Emek/Ankara
Country 17858 0
Phone 17858 0
Fax 17858 0
Email 17858 0
Contact person for scientific queries
Name 8786 0
Ramazan Yagci
Address 8786 0
Fatih University, Medical School
Alparslan Turkes C. No:57 06510 Emek/Ankara
Country 8786 0
Phone 8786 0
Fax 8786 0
Email 8786 0

No information has been provided regarding IPD availability
Summary results
Have study results been published in a peer-reviewed journal?
Other publications
Have study results been made publicly available in another format?
Results – basic reporting
Results – plain English summary