ANZCTR - Registration

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Trial registered on ANZCTR

Registration number

ACTRN12612000026820

Ethics application status

Approved

Date submitted

5/01/2012

Date registered

6/01/2012

Date last updated

4/08/2023

Date data sharing statement initially provided

12/03/2019

Date results provided

12/03/2019

Type of registration

Prospectively registered

Titles & IDs

Public title

The CAP Study: Evaluating a comprehensive universal and targeted intervention designed to prevent substance use and related harms in Australian adolescents

Scientific title

The CAP intervention: A comprehensive universal and targeted intervention to prevent substance use and related harms in Australian adolescents aged 13 to 15

Secondary ID [1]

APP1004744, APP1124958.

Universal Trial Number (UTN)

U1111-1121-8314

Trial acronym

CAP

Linked study record

Health condition

Health condition(s) or problem(s) studied:

Substance use prevention

Prevention of substance use-related harms

Condition category

Condition code

Mental Health

Addiction

Public Health

Other public health

Intervention/exposure

Study type

Interventional

Description of intervention(s) / exposure

Participating secondary schools will be randomly allocated to one of four groups. One group will serve as the control group and receive their usual drug education in school while the remaining three groups will receive either of the following interventions: Arm 1- Climate Schools Intervention (CL): The Climate Schools program aims to reduce the use of Australia’s most commonly used licit and illicit drugs: alcohol and cannabis, and related harms. The Program consists of twelve 40-minute lessons delivered as part of the Year 8 PDHPE syllabus. The lessons are delivered weekly for 6 weeks (Climate Schools Alcohol module) and then approximately a 6 month break before the delivery of another 6 weekly lessons (Climate Schools Alcohol and Cannabis module). The first part of each lesson is completed individually over the internet where students are engaged through cartoon storylines which impart information about the short- and long-term effects of alcohol and cannabis, normative alcohol and cannabis use, refusal skills, and first aid. The second part of each lesson is a group or class activity delivered by the teacher which reinforces the information in the cartoons and allows interactive communication between students. Teachers are provided with a manual containing the activities, implementation guidelines, links to the education syllabus and summaries for each lesson. The first six lessons focus specifically on alcohol and are delivered approximately six months prior to the remaining six lessons which focus on cannabis. The overall duration of Arm 1 is approximately 6 months. Arm 2- Preventure Intervention (PR): The Preventure program is a brief personality-targeted substance use preventive intervention for high-risk adolescents aged 13-15 years. Unlike universal programs, this selected personality-targeted approach addresses personality risk-factors for early-onset substance misuse and other risky behaviours. Participating students will be screened at baseline using the 24-item Substance Use Risk Profile (SURPS) questionnaire which assesses variation in personality risk for substance abuse along four dimensions: Sensation Seeking, Impulsivity, Anxiety Sensitivity and Hopelessness (Woicik et al., 2009). The Preventure program is also consistent with new models which conceptualise substance use as being driven by personality traits such as impulsivity and disinhibition (Dick et al., 2008). This program involves two 90-minute group sessions (6-8 students per group) delivered one week apart by a trained clinical psychologist and co-facilitator. The interventions are conducted using manuals which incorporate psycho-educational and cognitive behavioural components, and include real life scenarios shared by high-risk youth in specifically-organised focus groups. In the first session, participants are guided in a goal setting exercise, designed to enhance motivation to change behaviour. Psycho-educational strategies are used to teach participants about their target personality variable and associated problematic coping behaviours like avoidance, interpersonal dependence, aggression, risky behaviours and substance misuse. They are then introduced to the cognitive behavioural model and guided in breaking down personal experience according to the physical, cognitive and behavioural components of an emotional response. A novel component to this intervention approach is the fact that all exercises discuss thoughts, emotions and behaviours in a personality-specific way, e.g. identifying situational triggers and cognitive distortions related to Sensation Seeking specifically. In the second session, participants are encouraged to identify and challenge personality-specific cognitive distortions that lead to problematic behaviours. The overall duration of Arm 2 is approximately 3 months. Arm 3- Climate Schools and Preventure Intervention (CAP): The CAP intervention will deliver the Climate Schools and Preventure programs, described above, simultaneously with the aim of providing a comprehensive ‘universal’ and ‘targeted’ model to prevent substance use and related harms in Australian adolescents. The overall duration of Arm 3 is approximately 9 months.

CAP LONG TERM FOLLOW UP 2017-2019
Results at 3 years have shown the effectiveness of universal and selective approaches in preventing harmful alcohol use among low- and high-risk adolescents. The CAP long-term follow up is an opportunistic extension of the landmark CAP study, whereby follow up of this cohort will extend beyond the completion of secondary school and into the critical transition period of early adulthood. The investigators will extend longitudinal follow-up for a further 3 years, inviting the participants to take part in an two additional online surveys assessing demographic information, drinking and drug use habits, and behavioural and personality inventories

Intervention code [1]

Prevention

Intervention code [2]

Lifestyle

Intervention code [3]

Behaviour

Comparator / control treatment

The combined Climate Schools and Preventure (CAP) Intervention will be compared to:

a) A "standard treatment" control group - Students will not receive the Climate Schools or the Preventure Interventions. Participants will complete their standard Year 8 PDHPE classes, delivered by their teacher

b) Climate Schools only intervention - Students will receive 12 x 40minute lessons delivered as part of the Year 8 PDHPE syllabus. Each lesson consists of computer lessons and activities from the program manual, to be administered by the teacher

c) Preventure only intervention - Students will attend their standard PDHPE lessons, delivered by their teacher. Students who are identified as being 'high-risk' based on their personality profile will be invited to participate in 2 x 90minute sessions carried out by a registered Clinical Psychologist and co-facilitator. These sessions incorporate psycho-educational and cognitive behavioural components.

Control group

Active

Outcomes

Primary outcome [1]

Uptake and harmful use of alcohol and illicit substance

Timepoint [1]

Assessed at baseline and at 6, 12, 24 and 36 months after intervention commencement. Uptake and harmful use will be assessed by an adapted version of the School Health Alcohol Harm Reduction Project (SHAHRP) Patterns of Alcohol and Cannabis Use instrument, the Diagnostic Interview Schedule for Children (DISC-IV), the Alcohol and Lifestyle Questionnaire and nine items relating to student's current and intended future use of alcohol and illicit drugs.
Also, 5 questions will be included to assess student's intention to use alcohol and other drugs in the future.

Long-term follow-up:
Primary outcomes will be assessed long-term via the administration of 2 additional follow-up surveys spanning 5, 6 and 7 years post intervention.
Primary outcome 1: Drinking frequency and binge drinking will be assessed using an adapted version of the Patterns of Alcohol Index.

Primary outcome [2]

Substance use related harms

Timepoint [2]

Assessed at baseline and at 6, 12, 24 and 36 months after intervention commencement. Harms caused by cannabis will be assessed using 12 items adapted from the SHAHRP survey instrument and a set of questions adapted from the Adolescent Cannabis Problems Questionnaire. Harms caused by alcohol will be assessed using an abbreviated version of the Rutgers Alcohol Problem Index.

Long-term follow-up:
Primary outcomes will be assessed long-term via the administration of 2 additional follow-up surveys spanning 5, 6 and 7 years post intervention.
Primary outcome 2: Alcohol related harms will be measured using an abbreviated version of the Rutgers Alcohol Problem Index,

Primary outcome [3]

Alcohol and cannabis knowledge and attitudes

Timepoint [3]

Assessed at baseline and at 6, 12, 24 and 36 months after intervention commencement, assessed by questions adapted from the SHAHRP questionnaire, and the Cannabis Quiz.

Long-term follow-up:
Primary outcomes will be assessed long-term via the administration of 2 additional follow-up surveys spanning 5, 6 and 7 years post intervention.
Primary outcome 3: Probable diagnosis of alcohol use disorder will be measured using a self-report symptom checklist based on DSM-5 criteria.

Secondary outcome [1]

Mental health comorbidity

Timepoint [1]

Assessed at baseline and at 6, 12, 24 and 36 months after intervention commencement. Psychological distress will be assessed using the Kessler 6 Scale, depression and anxiety symptoms will be assessed using the Brief Symptom Inventory (BSI) and Psychotic symptoms will be measured using the Thoughts and Feelings Questionnaire

Secondary outcome [2]

Behavioural problems

Timepoint [2]

Assessed at baseline and at 6, 12, 24 and 36 months after intervention commencement. Behavioural problems will be assessed by The Strengths and Difficulties Questionnaire, the Reactive Proactive Aggression Questionnaire, and the Self-Regulatory Efficacy Scale.

Secondary outcome [3]

Other drug use

Timepoint [3]

Assessed at baseline and at 6, 12, 24 and 36 months after intervention commencement. Other drug use will be measured based on questions from the National Drug Strategy Household Survey 2010.

Secondary outcome [4]

Use of illicit drugs.

Timepoint [4]

Secondary outcomes will be assessed long-term via the administration of 2 additional follow-up surveys spanning 5, 6 and 7 years post intervention. Cannabis use will be assessed using cannabis questions from the National Drug Strategy Household Survey 2013, Cannabis-related harms will be assessed using a 6-item scale asking participants whether they experienced any of 6 different harms related to their cannabis use, Probable diagnosis of cannabis use disorder will be assessed using a self-report symptom checklist, and the use of ecstasy and methamphetamines will be measured using two items that ask whether participants have used ecstasy/MDMA or methamphetamines respectively in the past 6 months, and how many times they have used these substances.

Secondary outcome [5]

Assess efficacy of intervention in reducing aggression.

Timepoint [5]

Secondary outcomes will be assessed long-term via the administration of 2 additional follow-up surveys spanning 5, 6 and 7 years post intervention. Reactive proactive aggression will be measured using the Reactive-Proactive Aggression Questionnaire, and self-report violent behaviours will be measured using an adapted version of the Self-Reported Delinquency Scale.
To corroborate self-report measures and to further examine the criminal involvement of this group as well as hypothesised intervention effects on drug-related violent offending, consent will be sought to match participant data with court record data from the Bureau of Crime Statistics and Research (BOSCAR).

Secondary outcome [6]

Peer problems

Timepoint [6]

Assessed at baseline and at 6, 12, 24 and 36 months after intervention commencement. Peer problems will be assessed by the Bullying Questionnaire and the Personal Experience Checklist

Eligibility

Key inclusion criteria

Baseline: All students (male and female) between the ages of 12 and 15 yrs.

Long-term follow-up: Those that participated at baseline will be eligible to continue with the study, via the administration of 2 additional follow-up surveys spanning 5, 6 and 7 years post intervention.

Minimum age

12 Years

Maximum age

15 Years

Sex

Both males and females

Can healthy volunteers participate?

Yes

Key exclusion criteria

Baseline study: Those younger than 12 or older than 15 years of age.

Long-term follow-up: Those who did not participate in the baseline survey are not eligible to take part in the 2 long-term follow-up surveys spanning 5, 6, and 7 years post intervention.

Study design

Purpose of the study

Prevention

Allocation to intervention

Randomised controlled trial

Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)

Schools will be randomised to one of the four study groups using the online program Research Randomizer. Allocation will be concealed via central randomisation using computer software.

Methods used to generate the sequence in which subjects will be randomised (sequence generation)

Schools will be randomised to one of the four study groups using the online program Research Randomizer (simple randomisation using computer software).

Masking / blinding

Blinded (masking used)

Who is / are masked / blinded?

Intervention assignment

Factorial

Other design features

Phase

Not Applicable

Type of endpoint/s

Efficacy

Statistical methods / analysis

Recruitment

Recruitment status

Completed

Date of first participant enrolment

Anticipated

16/09/2011

Actual

1/02/2012

Date of last participant enrolment

Anticipated

Actual

30/09/2012

Date of last data collection

Anticipated

31/10/2019

Actual

23/09/2019

Sample size

Target

1920

Accrual to date

Final

2190

Recruitment in Australia

Recruitment state(s)

NSW,VIC

Funding & Sponsors

Funding source category [1]

Government body

Name [1]

National Health and Medical Research Council

Address [1]

National Health and Medical Research Council
GPO Box 1421
Canberra ACT 2601

Country [1]

Australia

Primary sponsor type

Individual

Name

Prof Maree Teesson

Address

The Matilda Centre for Research in Mental Health and Substance Use
Level 6, Jane Foss Russell Building (G02)
The University of Sydney
Darlington NSW 2006

Country

Australia

Secondary sponsor category [1]

University

Name [1]

University of Sydney

Address [1]

Level 6, Jane Foss Russell Building (G02)
The University of Sydney
Darlington NSW 2006

Country [1]

Australia

Other collaborator category [1]

University

Name [1]

Kings College

Address [1]

Addictions Department
Institute of Psychiatry
Kings College London WC2R 2LS

Country [1]

United Kingdom

Ethics approval

Ethics application status

Approved

Ethics committee name [1]

UNSW Human Research Ethics Committee

Ethics committee address [1]

University of NSW
Sydney NSW 2052

Ethics committee country [1]

Australia

Date submitted for ethics approval [1]

Approval date [1]

29/08/2011

Ethics approval number [1]

HREC 11274 and HREC 16881

Summary

Brief summary

The aim of the current proposal is to combine the effective universal Climate Schools and targeted Preventure programs into a comprehensive model to prevent substance use and related harms in adolescents. This model will be known as the CAP intervention. Delivering prevention using the proposed comprehensive approach offers a way of preventing substance use at a whole population level and has the potential to maximize outcomes for both high- and low-risk youth. This study will be the first time such intervention has been trailed, and will also be the first trial of a targeted substance use prevention program in Australia.

The approved extended long-term follow up will provide the first ever evaluation of the long-term effectiveness of combining universal and selective approaches to prevention and will examine the durability of intervention effects into the longer-term, over a 7-year period from adolescence to early adulthood.

Trial website

http://www.capstudy.org.au/

Trial related presentations / publications

Peer reviewed publications

Newton, N. C., Stapinski, L., Slade, T., Champion, K. E., Barrett, E., Chapman, C., Smout, A., Lawler, S., Mather, M., Castellanos-Ryan, N., Conrod, P. J., Teesson, M. Pathways to prevention: Protocol for the CAP (Climate and Preventure) Study to evaluate the long-term effectiveness of school-based universal, selective and combined alcohol misuse prevention into early adulthood. Submitted to BMC Public Health, 15th Dec, 2017.
Teesson, M., Newton, N. C., Slade, T., Carragher, N., Barrett, E. L., Champion, K. E., Kelly, E. V., Nair, N. K., Stapinski, L. A., Conrod, P. J. (2017). Combined universal and selective prevention for adolescent alcohol use: a cluster randomized controlled trial. Psychological Medicine, 47, 1761-1770.
Champion, K.E., Newton, N.C., Stapinski, L., Slade, T., Barrett, E.L & Teesson, M. (2016). A cross-validation trial of an Internet-based prevention program for alcohol and cannabis: results from a cluster randomised controlled trial. Australian & New Zealand Journal of Psychiatry, 50(1): 64-73.
Newton, N.C., Conrod, P., Slade, T., Carragher, N., Champion, K.E., Barrett, E.L., Kelly, E.V., Nair, N.K., Stapinski, L & Teesson, M. (2016). The long-term effectiveness of a selective, personality-targeted prevention program in reducing alcohol use and related harms: A cluster randomised controlled trial. Journal of Child Psychology and Psychiatry, 57:9, 1056–1065.
Barrett, E. L., Newton, N. C., Teesson, M., Slade, T., & Conrod, P. (2013). Adapting the personality-targeted Preventure program to prevent substance use and associated harms among high-risk Australian adolescents. Early Intervention in Psychiatry, 9(4): 308-15
Newton, N. C., Teesson, M., Barrett, E. L., Slade, T. & Conrod, P. (2012). The CAP study, evaluation of integrated universal and selective prevention strategies for youth alcohol misuse: Study protocol of a cluster randomized controlled trial. BMC Psychiatry, 12 (118), 1-10. DOI: 10.1186/1471-244X-12-118
Vogl, L. E., Teesson, M., Newton, N. C., & Andrews, G. (2012). Developing a school-based drug prevention program to overcome barriers to effective program implementation: The CLIMATE Schools: Alcohol Module. Open Journal of Preventive Medicine, 2 (3), 410-422. DOI: 10.4236/ojpm.2012.23059.

Presentations

Mather, M. (2017). Patterns and predictors of substance use and mental health problems in Australian adolescents: Results from the CAP and CSC studies. Poster presentation, National Drug and Alcohol Research Symposium, UNSW, Sydney, Australia, September, 2017
Mather, M. (2017). Patterns and predictors of substance use and mental health problems in Australian adolescents: Results from the CAP and CSC studies. Poster presentation, the International Federation of Psychiatric Epidemiology, Melbourne, Australia, October 2017
Newton, N.C. (2017). Pathways to prevention: The long-term effectiveness of universal, selective and personality targeted prevention for alcohol use. Invited plenary presentation at the 2017 National Drug and Alcohol Research Centre 30 year symposium. Sydney, October 3, 2017.
Newton, N. C., Stapinski, L., Slade, T., Conrod, P., Barrett, E., Chapman, C., Champion, K., Lawler, S., Smout, A., Mather, M., Castellanous-Ryan, N., Teesson, M. An innovative approach to preventing substance use and mental health problems among young Australians. Oral presentation, International Federation of Psychiatric Epidemiology, Melbourne, Australia, October 2017.
Newton, N. C. (2017). Pathways to prevention: The effectiveness of universal and selective prevention in altering the developmental pathways to alcohol related harms in young adults. Poster presentation, National Drug and Alcohol Research Symposium, UNSW, Sydney, Australia, September, 2017.
Smout, A. (2017). Pathways to prevention: The effectiveness of universal and selective prevention in altering the developmental pathways to alcohol related harms in young adults. Poster presentation, Society for Mental Health Research conference, Canberra, Australia, December, 2017.
Newton, N.C., Teesson, M., Slade, T., Stapinski, L., Carragher, N., Champion, K., Barrett. E. L. Kelly, E., Nair, N., & Conrod, P. (2016). Reducing alcohol use, alcohol-related harms, internalizing and externalizing problems among high-risk adolscents. Three year outcomes of selective, personality-targeted prevention. Oral presentation at the 2016 World Congress of Behavioural and Cognitive Therapies. Melbourne, June, 2016.
Champion, K.E., Newton, N.C., Stapinski, L., Slade, T., Barrett, E.L. & Teesson, M.    Internet-based prevention for alcohol, cannabis, ecstasy and new psychoactive substances: outcomes from two cluster randomised controlled trials. Third National Cannabis Conference, Melbourne, 9th October 2015 (Invited Presentation).
N.C. Newton, M. Teesson, T. Slade, L. Stapinski, N. Carragher, K.E. Champion, E.L. Barrett, E.V Kelly, N. Nair & P. Conrod. Three-year outcomes of a selective, personality-targeted prevention program: Reducing alcohol use, alcohol related-harms, internalising and externalising problems among adolescents. National Drug and Alcohol Research Centre Annual Symposium, Sydney, Australia, September 2015.
Newton, N.C., Conrod, P., Slade, T., Carragher, N., Stapinski, L., Champion, K., Barrett, E., Kelly, E., Nair, N., Stapinski, L. & Teesson, M. The effectiveness of a selective, personality-targeted prevention program in reducing alcohol use and related harms over three years: a cluster randomized controlled trial. Symposium presentation at the Society for Mental Health Research 2015 Conference, Brisbane, December 2015.
Barrett EL*, Newton NC, Teesson M, Slade T, Conrod P, Champion K, Kelly E, Rosenfeld J, Swaffield L. The CAP study: Preventing substance use and related harms among Australian adolescents. NHMRC National Centre of Research Excellence in Mental Health and Substance Use (CREMS) Conference, Melbourne, August 2014
E.L. Barrett*, N.C. Newton, M. Teesson, P. Conrod, T. Slade, K.E. Champion, E. Kelly, J. Rosenfeld, N. Nair. A comprehensive intervention to prevent substance use and associated harms among Australian adolescents. Oral presentation at the NHMRC National Centre of Research Excellence in Mental Health and Substance Use Conference. Perth, Australia, August 2014.
K.E. Champion, N.C. Newton, L. Stapinski, T. Slade, E.L. Barrett & M. Teesson. A cross-validation trial of a universal prevention program for alcohol and cannabis: 6-month outcomes. National Drug and Alcohol Research Centre Annual Symposium, Sydney, Australia, September 2014.
K.E. Champion, N.C. Newton, L. Stapinski, T. Slade, E.L. Barrett & M. Teesson. Delivering Internet-based prevention for alcohol and cannabis: results from a cluster randomised controlled trial. Inaugural Postgraduate Research Symposium, University of NSW, Sydney, Australia, August 2014. 
N.C. Newton, M. Teesson, P. Conrod, T. Slade, K. Champion*, N. Nair, E. Kelly*, N. Carragher. & E. Barrett. Innovative interventions to prevent substance use and mental health concerns: A comprehensive intervention to prevent substance use and associated harms in Australian adolescents. Invited presentation at the ‘NHMRC Substance use and mental health’ pre-conference workshop, Australasian Professional Society on Alcohol and Other Drugs Conference, Adelaide, Australia, November 2014. 
N.C. Newton, M. Teesson, P. Conrod, T. Slade*, K.E. Champion, N. Nair, E. Kelly, N. Carragher & E.L. Barrett. An integrated approach to preventing substance use in adolescents: 12-month outcomes of the CAP (Climate and Preventure) intervention. Society for Mental Health Research Annual Conference, Adelaide, December 2014.
N.C. Newton, M. Teesson*, P. Conrod, T. Slade, K. Champion, N. Nair, E. Kelly, N. Carragher & E.L. Barrett	An integrated approach to preventing substance use in adolescents: 12-month outcomes of the CAP (Climate and Preventure) intervention. Australasian Professional Society on Alcohol and Other Drugs Conference, Adelaide, 11th Nov 2014.
Barrett, E., Newton, N. C., Teesson, M., Slade, T., & Conrod, P. (2013). An integrated approach to preventing substance use in adolescents: Developing the CAP intervention. Presented at the European Association for Behavioural and Cognitive Therapies Congress, Marrakech, 25-28 September 2013.
K.E. Champion, N.C. Newton, M. Teesson, E.L. Barrett, & T. Slade. A Cross-Validation Trial of the Internet-Based Climate Schools: Alcohol and Cannabis Course. National Drug and Alcohol Research Centre Annual Symposium, Sydney, Australia, September 2013.
K.E. Champion, N.C. Newton, M. Teesson, E.L. Barrett, & T. Slade. Preliminary results from a cross-validation trial of the internet-based Climate Schools: Alcohol and Cannabis course. Australasian Society for Behavioural Health and Medicine 10th Annual Scientific Conference, Newcastle, Australia, February 2013.
K.E. Champion, N.C. Newton, M. Teesson, E.L. Barrett, & T. Slade. A Cross-Validation Trial of the Internet-Based Climate Schools: Alcohol and Cannabis Course in Sydney, Australia. NIDA International Poster Session, Society for Prevention Research 21st Annual Meeting, San Francisco, USA, May 2013.
M. Teesson*, N.C. Newton, T. Slade, P. Conrod, K. Champion, E. Barrett, N. Nair & E. Kelly. The CAP intervention: A comprehensive model for substance use prevention. Poster presented at the 36th Annual Research Society on Alcoholism Meeting, Orlando, United States, June 2013.
Teesson, M*., Newton, N.C., Slade, T., & Conrod, P. (2013). An integrated approach to preventing substance use in adolescents: Developing the CAP intervention.  Presented at the 43rd Annual Congress for the European Association for Behavioural and Cognitive Therapies (EABCT), Marrakech, Morocco, September 2013.
Barrett, E., Newton, N. C., Teesson, M., Slade, T., & Conrod, P. (2012). Modifying the personality-targeted ‘Preventure’ program for use with Australian adolescents. Presented at the 35th Research Society on Alcoholism Conference, San Francisco, United States, June 27th 2012. 
Champion K, Newton NC, Teesson M, Barrett EL, Slade T. Preliminary results from a cross-validation trial of the internet-based Climate Schools: Alcohol and Cannabis course. Conference of the Australasian Professional Society on Alcohol and Other Drugs. Melbourne (Nov 2012).
Newton NC, Teesson M, Conrod P, Slade T, Barrett EL, Champion K. An integrated approach to preventing substance use in adolescents: Developing the CAP intervention and baseline characteristics of the sample. Conference of the Australasian Professional Society on Alcohol and Other Drugs. Melbourne (Nov 2012)
Newton, N. C. (2012). Can we really prevent drug and alcohol problems in young people? Invited speaker at Advances in Public Health and Health Services Research at UNSW: 2012 Annual Research Symposium, Sydney, Australia, September 21st 2012.
Newton, N. C. (2012). An integrated approach to prevention in schools. Presented at the National Drug and Alcohol Research Centre Annual Symposium, Sydney, Australia, August 28th 2012.
Newton, N. C., Teesson, M., Conrod, P., Slade, T., & Barrett, E. (2012). Developing the CAP intervention: A comprehensive model to alcohol and other drug prevention. Presented at the 35th Research Society on Alcoholism Conference, San Francisco, United States, June 27th 2012, and at the National Drug and Alcohol Research Centre in house seminar, Sydney, NSW, May 31st 2012
N.C. Newton, M. Teesson, P. Conrod, T. Slade, E.L. Barrett & K.E. Champion (2012). Developing the CAP intervention: A comprehensive model to alcohol and other drug prevention. Presented at the National Drug and Alcohol Research Centre in house seminar, Sydney, Australia, May 2012.
Newton, N. C., Teesson, M., Conrod, P., Slade, T., Andrews, G. (2011). The CAP intervention: A comprehensive model to substance use prevention. Poster presented at EABCT conference, Iceland, September 2011.

Public notes

Long-term follow-up extended for a further 3 years.

Contacts

Principal investigator

Name

Prof Prof Maree Teesson

Address

National Drug and Alcohol Research Centre University of NSW Sydney NSW 2052

Country

Australia

Phone

+612 9385 0333

Fax

+612 9385 0222

m.teesson@unsw.edu.au

Contact person for public queries

Name

Dr Nicola Newton

Address

National Drug and Alcohol Research Centre
University of NSW
Sydney NSW 2052

Country

Australia

Phone

+612 9385 0204

Fax

+612 9385 0222

nickien@unsw.edu.au

Contact person for scientific queries

Name

Prof Maree Teesson

Address

National Drug and Alcohol Research Centre
University of NSW
Sydney NSW 2052

Country

Australia

Phone

+612 9385 0333

Fax

+612 9385 0222

m.teesson@unsw.edu.au

Data sharing statement

Will individual participant data (IPD) for this trial be available (including data dictionaries)?

Yes

What data in particular will be shared?

De-identified individual participant survey data from all assessment waves (baseline, 6-, 12-, 15-, 18-, 24-, 30-, 60- and 72- month follow-ups)

When will data be available (start and end dates)?

Waves 1-9: available from 1st July 2022 until 1st July 2042

Available to whom?

Data are potentially available to researchers from not-for-profile organizations, commercial organisations/other and based in any location.
All data requests will be considered by the primary sponsor on a case-by-case basis. Requests must include a methodologically sound proposal. Specific conditions of use may apply and will be specified in a data sharing agreement (or similar) that the requester must agree to before access is granted.
The statistical analysis code (syntax) and data collected for the study, including de-identified participant data, will be made available to researchers on request to the corresponding author and with appropriate reason when accompanied by study protocol and analysis plan.
Data will be shared after the approval of a proposal by a committee of the current research team with a signed data access agreement. Informed consent forms are available in the published protocol.
For further information, see our data sharing policy (https://www.sydney.edu.au/policies/showdoc.aspx?recnum=PDOC2014/366&RendNum=0).

Available for what types of analyses?

Any type of analysis (IPD meta-analysis, systematic review, and other research questions) assessed on a case-by-case basis.

How or where can data be obtained?

As of 1st July 2022, access can be requested via this google form. Data request will be reviewed on a case by case basis
For further information, see our data sharing policy - (https://www.sydney.edu.au/policies/showdoc.aspx?recnum=PDOC2014/366&RendNum=0).

What supporting documents are/will be available?

Type	Other Details	Attachment
Informed consent form	Active student consent	347906-(Uploaded-12-03-2019-09-33-01)-Study-related document.docx
Informed consent form	Passive parent consent	347906-(Uploaded-12-03-2019-09-34-08)-Study-related document.docx
Ethical approval		347906-(Uploaded-12-03-2019-09-36-08)-Study-related document.pdf
Study protocol	CAP long-term follow-up protocol	347906-(Uploaded-12-03-2019-11-21-56)-Study-related document.pdf
Study protocol	CAP trial protocol	347906-(Uploaded-12-03-2019-11-22-38)-Study-related document.pdf
	Newton, N. C., Stapinski, L., Slade, T., Champion,... [More Details]

Results publications and other study-related documents

Documents added manually

Type	Is Peer Reviewed?	Citations or Other Details	Attachment
Study results article	Yes	Newton, N. C., Teesson, M., Slade, T., Carragher... [More Details]
Conference abstract	No	Presented at the 39th annual meeting of the Societ... [More Details]	347906-(Uploaded-12-03-2019-10-23-30)-Other results publication.docx
Study results article	Yes	Newton, N. C., Teesson, M., Mather, M., Champion... [More Details]
Study results article	Yes	Newton, N. C., Stapinski, L., Teesson, M., Slade, ... [More Details]
Study results article	Yes	Slade, T., Newton, N.C., Mathers, M., Barrett, E.,... [More Details]
Conference abstract	No	Newton, N.C. (2017). Pathways to prevention: The l... [More Details]
Conference abstract	No	Newton, N. C., Stapinski, L., Slade, T., Conrod, P... [More Details]
Conference abstract	No	Newton, N. C., Stapinski, L., Slade, T., Champion,... [More Details]
Conference abstract	No	Newton, N. C., Stapinski, L., Slade, T., Champion,... [More Details]

Documents added automatically

Source	Title	Year of Publication	DOI
Embase	A cross-validation trial of an Internet-based prevention program for alcohol and cannabis: Preliminary results from a cluster randomised controlled trial.	2016	https://dx.doi.org/10.1177/0004867415577435
Embase	The validity of the Substance Use Risk Profile Scale (SURPS) among Australian adolescents.	2016	https://dx.doi.org/10.1016/j.addbeh.2015.09.015
Embase	Pathways to prevention: protocol for the CAP (Climate and Preventure) study to evaluate the long-term effectiveness of school-based universal, selective and combined alcohol misuse prevention into early adulthood.	2018	https://dx.doi.org/10.1186/s12889-018-5554-y
Embase	A Novel Approach to Tackling Bullying in Schools: Personality-Targeted Intervention for Adolescent Victims and Bullies in Australia.	2020	https://dx.doi.org/10.1016/j.jaac.2019.04.010
Embase	Evaluating the differential effectiveness of social influence and personality-targeted alcohol prevention on mental health outcomes among high-risk youth: A novel cluster randomised controlled factorial design trial.	2020	https://dx.doi.org/10.1177/0004867419877948
Embase	Is Adolescent Alcohol Use Linked to Spikes in Aggressive Behaviour? A Growth Curve Analysis.	2021	https://dx.doi.org/10.1007/s11121-020-01188-2
Embase	The 7-Year Effectiveness of School-Based Alcohol Use Prevention From Adolescence to Early Adulthood: A Randomized Controlled Trial of Universal, Selective, and Combined Interventions.	2022	https://dx.doi.org/10.1016/j.jaac.2021.10.023

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