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Trial registered on ANZCTR

Registration number
Ethics application status
Date submitted
Date registered
Date last updated
Type of registration
Prospectively registered

Titles & IDs
Public title
Help-seeking for postnatal depression as a major public health problem: A cluster randomised controlled trial of motivational interviewing
Scientific title
Motivational interviewing to facilitate help-seeking for postnatal depression by mothers in the first year following childbirth: A cluster randomised controlled trial
Secondary ID [1] 262288 0
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Postnatal Depression 267999 0
Condition category
Condition code
Mental Health 268127 268127 0 0

Study type
Description of intervention(s) / exposure
Motivational Interviewing. Maternal and child health (MCH) nurses in this condition will receive training in motivational interviewing over two, 5-6 hour interactive small group sessions. Training will be provided by a psychologist experienced in motivational interviewing and will cover the "Spirit", principles and core skills of motivational interviewing. MCH nurses will then deliver a brief motivational interviewing intervention (approximately 10 minutes) during their routine appointments with new mothers at 4-weeks, 8-weeks and 4-months postpartum. The MCH nurses will follow a detailed manual and will receive a supervision session by telephone around two weeks after the training sessions (approximately 20 minutes). The motivational interviewing intervention provides guidance for MCH nurses about the way to talk with mothers about how they are managing.
Intervention code [1] 266684 0
Other interventions
Comparator / control treatment
Standard care. Maternal and child health (MCH) nurses in this condition will continue to follow their usual practice when talking with mothers about how they are managing.
Control group

Primary outcome [1] 266876 0
Percentage of participants reporting that they sought help for personal-emotional problems as measured by a dichotomous variable (yes/no)
Timepoint [1] 266876 0
7-weeks, 15-weeks and 12-months postpartum
Secondary outcome [1] 276548 0
Beck Depression Inventory Score
Timepoint [1] 276548 0
7-weeks, 15-weeks and 12-months postpartum

Key inclusion criteria
Ability to understand spoken and written English.
Minimum age
18 Years
Maximum age
No limit
Can healthy volunteers participate?
Key exclusion criteria

Study design
Purpose of the study
Educational / counselling / training
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Centralised administration of a coded, pre-generated allocation schedule by an independent person blind to coding. Allocation is concealed from researchers and maternal and child health nurses until the point of allocation.
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
A variable-length permuted blocks, computer-generated random sequence. The allocation schedule has been stratified by municipality.
Masking / blinding
Blinded (masking used)
Who is / are masked / blinded?

Intervention assignment
Other design features
Not Applicable
Type of endpoint(s)
Statistical methods / analysis

Recruitment status
Date of first participant enrolment
Date of last participant enrolment
Date of last data collection
Sample size
Accrual to date
Recruitment in Australia
Recruitment state(s)

Funding & Sponsors
Funding source category [1] 267174 0
Name [1] 267174 0
Australian Rotary Health
Address [1] 267174 0
PO Box 3455
Parramatta NSW 2124
Country [1] 267174 0
Primary sponsor type
Professor Jeannette Milgrom
Parent-Infant Research Institute
Level 1, South Wing, Centaur Building
Heidelberg Repatriation Hospital
300 Waterdale Rd
Hiedelberg Heights VIC 3081
Secondary sponsor category [1] 266248 0
Name [1] 266248 0
Address [1] 266248 0
Country [1] 266248 0

Ethics approval
Ethics application status
Ethics committee name [1] 269167 0
Austin Health Human Research Ethics Committee
Ethics committee address [1] 269167 0
Henry Buck Building
Austin Hospital
145 studley Rd
Heidelberg VIC 3084
Ethics committee country [1] 269167 0
Date submitted for ethics approval [1] 269167 0
Approval date [1] 269167 0
Ethics approval number [1] 269167 0

Brief summary
Around 30,000 women annually suffer from postnatal depression (PND) and untreated depression has negative long-term consequences for mothers and infants. Figures from previous research indicate that only 30-50% of women who are distressed in the perinatal period seek treatment. Currently, no effective, evidence-based strategy to enhance access to services exists. There is an urgent need to redress this and determine whether we can improve uptake of treatment by women experiencing PND. The aim of this study is to examine whether a brief motivational interviewing intervention delivered in the context of a routine postnatal screening and emotional health assessment improves access to treatment when women experience PND. The key concept is to prepare and motivate women to take action for their own emotional health needs in the year following childbirth. Motivational interviewing has shown enormous success in other fields of healthcare.
Trial website
Trial related presentations / publications
Public notes

Principal investigator
Name 32685 0
Address 32685 0
Country 32685 0
Phone 32685 0
Fax 32685 0
Email 32685 0
Contact person for public queries
Name 15932 0
Dr Charlene Schembri
Address 15932 0
Parent-Infant Research Institute
Heidelberg Repatriation Hospital
300 Waterdale Rd
Heidelberg Heights VIC 3081
Country 15932 0
Phone 15932 0
+61 3 9496 4496
Fax 15932 0
+61 3 9496 4148
Email 15932 0
Contact person for scientific queries
Name 6860 0
Dr Charlene Schembri
Address 6860 0
Parent-Infant Research Institute
Heidelberg Repatriation Hospital
300 Waterdale Rd
Heidelberg Heights VIC 3081
Country 6860 0
Phone 6860 0
+61 3 9496 4496
Fax 6860 0
+61 3 9496 4148
Email 6860 0

No information has been provided regarding IPD availability
Summary results
No Results