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Trial details imported from ClinicalTrials.gov
For full trial details, please see the original record at
https://clinicaltrials.gov/study/NCT07042789
Registration number
NCT07042789
Ethics application status
Date submitted
4/06/2025
Date registered
29/06/2025
Date last updated
29/06/2025
Titles & IDs
Public title
Perception of Health Promotion Messages
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Scientific title
Perception of Health Promotion Messages
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Secondary ID [1]
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2024/HE000725
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Universal Trial Number (UTN)
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Trial acronym
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Linked study record
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Health condition
Health condition(s) or problem(s) studied:
Perception of Vaping
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Condition category
Condition code
Intervention/exposure
Study type
Interventional
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Description of intervention(s) / exposure
Other interventions - Material source: AI generated ads vs existing ads by health agency
Other interventions - source labelling conditions: control condition, AI condition, health agency condition, combined condition
Experimental: Control - Ads presented without any source labelling
Experimental: AI condition - Ads labelled with the text "Made with AI"
Experimental: Health authority condition - Ads labelled with the text "Made by the World Health Organization (WHO)"
Experimental: Combined condition - Ads labelled with the text "Made with AI, by the World Health Organization (WHO)"
Other interventions: Material source: AI generated ads vs existing ads by health agency
Each participant evaluated 50 ads in random order, of which 25 were AI-generated through youth co-design process, and 25 were existing ads from official health agencies.
Other interventions: source labelling conditions: control condition, AI condition, health agency condition, combined condition
Participants were randomly assigned to one of four source labelling conditions: (1) Control (ads presented without any source labelling), (2) AI condition (ads labelled with the text "Made with AI"), (3) Health agency condition (ads labelled with the text "Made by the World Health Organization (WHO)"), and (4) Combined condition (ads labelled with the text "Made with AI, by the World Health Organization (WHO)").
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Intervention code [1]
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Other interventions
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Comparator / control treatment
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Control group
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Outcomes
Primary outcome [1]
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Perceived Message Effectiveness (PME)
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Assessment method [1]
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Each ad was rated with five items adapted from the validated University of North Carolina PME Scale for Youth. Two items assessed effects perceptions, i.e. the ads' potential to change attitudes and behaviours, and three items assessed ad perceptions, i.e., judgements about ad characteristics.
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Timepoint [1]
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Within 30mins of exposure
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Secondary outcome [1]
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Vaping and Smoking Behaviour
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Assessment method [1]
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Questions regarding participants' experience with cigarettes/other tobacco products, and e-cigarettes/vapes. These measures allow for the classification of participants according to their smoking and vaping status and are adapted from the National Drug Strategy Household Survey (NDSHS) 2019.
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Timepoint [1]
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Within 30mins of exposure
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Secondary outcome [2]
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Vaping susceptibility
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Assessment method [2]
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For participants who have never vaped, susceptibility to vaping will be assessed using a 3-item scale adapted from past studies (Noar et al., 2020). The items assess how likely it is that the respondent will: (1) use an e-cigarette or vape soon, (2) use an e-cigarette or vape in the next year and (3) if one of your best friends were to offer you an e-cigarette or vape, would you use it?
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Timepoint [2]
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Within 30mins of exposure
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Secondary outcome [3]
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Intention to quit
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Assessment method [3]
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For participants who are currently vaping, the question "Are you currently thinking about quitting vaping?" will be asked.
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Timepoint [3]
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Within 30mins of exposure
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Secondary outcome [4]
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Health behaviour
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Assessment method [4]
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Participants will be asked 13 questions regarding their current health behaviours modified from Hampson et al. (2019) version, with too similar questions removed and three questions modified to better suit the focus of this study. These questions measure what current actions are being done to protect ones own health.
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Timepoint [4]
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Within 30mins of exposure
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Secondary outcome [5]
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Trust in health agencies
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Assessment method [5]
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Participants will be asked 14 questions regarding their trust in public health authorities adapted from Holroyd et al. (2021), to investigate the possible relationship between trust in authorities and trust in health adverts.
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Timepoint [5]
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Within 30mins of exposure
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Secondary outcome [6]
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Demographics
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Assessment method [6]
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Information on age, gender, indigeneity, subjective financial situation and the primary language spoken at home will be collected. These measures are designed to detail the profile of the study participants and were adapted from the NDSHS 2019, the Williams Institute (2014) and Williams et al., (2017).
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Timepoint [6]
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Within 30mins of exposure
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Secondary outcome [7]
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General attitudes towards artificial intelligence scale (GAAIS)
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Assessment method [7]
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Participants will answer 20 items about their attitudes towards AI which is adapted from Schepman and Rodway (2023) to investigate the relationship between labelling and negative attitudes towards AI.
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Timepoint [7]
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Within 30mins of exposure
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Eligibility
Key inclusion criteria
* Living in Australia
* Aged 16-25 years
* Able to read English
* Committed to reviewing each advertisement and providing honest, personal responses
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Minimum age
16
Years
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Maximum age
25
Years
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Sex
Both males and females
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Can healthy volunteers participate?
Yes
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Key exclusion criteria
* Unwilling to commit to reviewing each advertisement honestly
* Unable to promise to provide genuine responses to survey questions
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Study design
Purpose of the study
Prevention
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Allocation to intervention
Randomised controlled trial
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Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
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Methods used to generate the sequence in which subjects will be randomised (sequence generation)
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Masking / blinding
Blinded (masking used)
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Who is / are masked / blinded?
The people receiving the treatment/s
The people analysing the results/data
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Intervention assignment
Factorial
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Other design features
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Phase
Not applicable
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Type of endpoint/s
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Statistical methods / analysis
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Recruitment
Recruitment status
Completed
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Data analysis
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Reason for early stopping/withdrawal
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Other reasons
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Date of first participant enrolment
Anticipated
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Actual
24/08/2024
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Date of last participant enrolment
Anticipated
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Actual
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Date of last data collection
Anticipated
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Actual
20/11/2024
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Sample size
Target
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Accrual to date
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Final
763
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Recruitment in Australia
Recruitment state(s)
QLD
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Recruitment hospital [1]
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National Centre for Youth Substance Use Research - Brisbane
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Recruitment postcode(s) [1]
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4068 - Brisbane
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Funding & Sponsors
Primary sponsor type
Other
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Name
The University of Queensland
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Address
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Country
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Ethics approval
Ethics application status
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Summary
Brief summary
The specific aims of this study are: 1. To compare the perceived message effectiveness (PME) of AI-generated vaping prevention materials with existing traditionally generated (typically by a health authority) prevention materials in a sample of young people. This aim addresses the gap in understanding whether AI can match or exceed the effectiveness of traditional prevention materials in changing youth perceptions and intentions of vaping. 2. To examine the impact of ad labelling (AI-generated, AI-generated with health authority endorsement, and unlabelled) on the PME of vaping prevention messages. Given the novelty of AI in this context, understanding the influence of transparency about message origin and endorsements on message reception is critical.
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Trial website
https://clinicaltrials.gov/study/NCT07042789
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Trial related presentations / publications
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Public notes
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Contacts
Principal investigator
Name
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Address
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Country
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Phone
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Fax
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Email
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Contact person for public queries
Name
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Address
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Country
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Phone
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Fax
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Email
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Contact person for scientific queries
Data sharing statement
Will individual participant data (IPD) for this trial be available (including data dictionaries)?
No
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No/undecided IPD sharing reason/comment
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What supporting documents are/will be available?
No Supporting Document Provided
Results publications and other study-related documents
No documents have been uploaded by study researchers.
Results not provided in
https://clinicaltrials.gov/study/NCT07042789
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