Please note the ANZCTR will be unattended from Friday 20 December 2024 for the holidays. The Registry will re-open on Tuesday 7 January 2025. Submissions and updates will not be processed during that time.

Registering a new trial?

To achieve prospective registration, we recommend submitting your trial for registration at the same time as ethics submission.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been endorsed by the ANZCTR. Before participating in a study, talk to your health care provider and refer to this information for consumers
Trial details imported from ClinicalTrials.gov

For full trial details, please see the original record at https://clinicaltrials.gov/study/NCT05754957




Registration number
NCT05754957
Ethics application status
Date submitted
23/02/2023
Date registered
6/03/2023

Titles & IDs
Public title
A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Scientific title
A Phase 3, Randomized, Double-blind, Placebo-controlled, Event-driven Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, After a Recent Acute Coronary Syndrome
Secondary ID [1] 0 0
70033093ACS3003
Secondary ID [2] 0 0
CR109271
Universal Trial Number (UTN)
Trial acronym
LIBREXIA-ACS
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Acute Coronary Syndrome 0 0
Condition category
Condition code
Cardiovascular 0 0 0 0
Coronary heart disease
Other 0 0 0 0
Research that is not of generic health relevance and not applicable to specific health categories listed above

Intervention/exposure
Study type
Interventional
Description of intervention(s) / exposure
Treatment: Drugs - Milvexian
Other interventions - Placebo

Experimental: Milvexian - Participants enrolled within 7 days of an acute coronary syndrome (ACS), who have undergone cardiac catheterization with percutaneous intervention (PCI) or who are being managed conservatively with or without catheterization, and who are receiving antiplatelet therapy standard-of-care (single antiplatelet therapy \[SAPT\] or dual antiplatelet therapy \[DAPT\]) as determined by the investigator will receive milvexian 25 milligrams (mg), orally, twice daily.

Placebo comparator: Placebo - Participants enrolled within 7 days of an ACS, who have undergone cardiac catheterization with PCI or who are being managed conservatively with or without catheterization, and who are receiving antiplatelet therapy standard-of-care (SAPT or DAPT) as determined by the investigator will receive placebo orally, twice daily.


Treatment: Drugs: Milvexian
Milvexian will be administered orally.

Other interventions: Placebo
Placebo will be administered orally.

Intervention code [1] 0 0
Treatment: Drugs
Intervention code [2] 0 0
Other interventions
Comparator / control treatment
Control group

Outcomes
Primary outcome [1] 0 0
Time to First Occurrence of Major Adverse Cardiovascular Event (MACE)
Timepoint [1] 0 0
Up to 3 years 6 months
Secondary outcome [1] 0 0
Time to the First Occurrence of Major Adverse Vascular Event (MAVE)
Timepoint [1] 0 0
Up to 3 years 6 months
Secondary outcome [2] 0 0
Time to the First Occurrence of Composite of All-cause Mortality (ACM), Myocardial Infarction (MI) and Ischemic Stroke
Timepoint [2] 0 0
Up to 3 years 6 months
Secondary outcome [3] 0 0
Time to Cardiovascular (CV) Death
Timepoint [3] 0 0
Up to 3 years 6 months
Secondary outcome [4] 0 0
Time to All-cause Mortality (ACM)
Timepoint [4] 0 0
Up to 3 years 6 months

Eligibility
Key inclusion criteria
* Participants must have an index event that meets all 3 of the following criteria within 7 days prior to randomization: a) clinical syndrome consistent with spontaneous cardiac ischemia, b) diagnosis of acute coronary syndrome (ACS) (that is, ST-elevation myocardial infarction [STEMI], non-STEMI, or unstable angina [UA]), c) cardiac biomarker elevation (example, troponin I, troponin T, creatine kinase-MB [CK-MB]) above the upper limit of normal as determined by the local laboratory
* Participants must have at least 2 of the following risk factors:a) age 65 or older, b) diabetes mellitus, c) history of a prior myocardial infarction (MI) (other than index ACS event), d) multivessel coronary artery disease (CAD), e) history of coronary artery bypass graft (CABG) surgery prior to index ACS event, f) history of peripheral artery disease (PAD) or cerebrovascular disease (example, carotid atherosclerosis, intracranial artery stenosis, g) conservative management (that is, no percutaneous intervention [PCI] or CABG after index ACS event), h) Any one or more of the following high-risk angiographic features i) total stent length of greater than (>) 30 millimeters (mm), ii) thrombotic target lesion, iii) bifurcation lesion treated with more than one stent, iv) calcified target lesion treated with atherectomy, v) treatment of obstructive left main or proximal left anterior descending artery for index ACS (or clinical diagnosis of an anterior STEMI)
* All female participants of childbearing potential must have a negative highly sensitive serum beta-human chorionic gonadotropin (hCG) or urine test at screening
* A female participant must not be pregnant, breastfeeding, or planning to become pregnant until 4 days (5 half-lives) after the last dose of study intervention
Minimum age
18 Years
Maximum age
No limit
Sex
Both males and females
Can healthy volunteers participate?
No
Key exclusion criteria
* MI secondary to ischemia due to either increased oxygen demand or decreased supply (Type 2 MI) or periprocedural MI as the index ACS event
* Planned CABG or staged PCI after randomization
* Any condition that requires chronic anticoagulation at the discretion of the investigator and/or local guidelines
* Conditions with a significant increased risk of bleeding (example, clinically significant bleeding within previous 3 months, known bleeding diathesis, et cetera)

Study design
Purpose of the study
Treatment
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Masking / blinding
Blinded (masking used)
Who is / are masked / blinded?
The people receiving the treatment/s
The people administering the treatment/s
The people assessing the outcomes
The people analysing the results/data
Intervention assignment
Parallel
Other design features
Phase
Phase 3
Type of endpoint/s
Statistical methods / analysis

Recruitment
Recruitment status
Recruiting
Data analysis
Reason for early stopping/withdrawal
Other reasons
Date of first participant enrolment
Anticipated
Actual
Date of last participant enrolment
Anticipated
Actual
Date of last data collection
Anticipated
Actual
Sample size
Target
Accrual to date
Final
Recruitment in Australia
Recruitment state(s)
Recruitment hospital [1] 0 0
Royal Adelaide Hospital - Adelaide
Recruitment hospital [2] 0 0
Flinders Medical Centre - Adelaide
Recruitment hospital [3] 0 0
Ballarat Base Hospital - Ballarat
Recruitment hospital [4] 0 0
Sunshine Coast University Hospital - Birtinya
Recruitment hospital [5] 0 0
Cairns Base Hospital - Cairns
Recruitment hospital [6] 0 0
Royal Prince Alfred Hospital - Camperdown
Recruitment hospital [7] 0 0
Concord Repatriation General Hospital - Concord
Recruitment hospital [8] 0 0
The Canberra Hospital - Garran
Recruitment hospital [9] 0 0
Royal Brisbane and Women's Hospital - Herston
Recruitment hospital [10] 0 0
Royal Hobart Hospital - Hobart
Recruitment hospital [11] 0 0
Nepean Hospital - Kingswood
Recruitment hospital [12] 0 0
Core Research Group - Milton
Recruitment hospital [13] 0 0
Fiona Stanley Hospital - Murdoch
Recruitment hospital [14] 0 0
Gold Coast University Hospital - Southport
Recruitment hospital [15] 0 0
Westmead Hospital - Sydney
Recruitment hospital [16] 0 0
Latrobe Regional Hospital - Traralgon
Recruitment hospital [17] 0 0
The Queen Elizabeth Hospital - Woodville South
Recruitment postcode(s) [1] 0 0
5000 - Adelaide
Recruitment postcode(s) [2] 0 0
5042 - Adelaide
Recruitment postcode(s) [3] 0 0
3350 - Ballarat
Recruitment postcode(s) [4] 0 0
4575 - Birtinya
Recruitment postcode(s) [5] 0 0
4870 - Cairns
Recruitment postcode(s) [6] 0 0
2050 - Camperdown
Recruitment postcode(s) [7] 0 0
2139 - Concord
Recruitment postcode(s) [8] 0 0
2605 - Garran
Recruitment postcode(s) [9] 0 0
4029 - Herston
Recruitment postcode(s) [10] 0 0
7000 - Hobart
Recruitment postcode(s) [11] 0 0
2747 - Kingswood
Recruitment postcode(s) [12] 0 0
4064 - Milton
Recruitment postcode(s) [13] 0 0
6150 - Murdoch
Recruitment postcode(s) [14] 0 0
4215 - Southport
Recruitment postcode(s) [15] 0 0
2145 - Sydney
Recruitment postcode(s) [16] 0 0
3844 - Traralgon
Recruitment postcode(s) [17] 0 0
5011 - Woodville South
Recruitment outside Australia
Country [1] 0 0
United States of America
State/province [1] 0 0
Alabama
Country [2] 0 0
United States of America
State/province [2] 0 0
Arizona
Country [3] 0 0
United States of America
State/province [3] 0 0
Arkansas
Country [4] 0 0
United States of America
State/province [4] 0 0
California
Country [5] 0 0
United States of America
State/province [5] 0 0
Colorado
Country [6] 0 0
United States of America
State/province [6] 0 0
Connecticut
Country [7] 0 0
United States of America
State/province [7] 0 0
Florida
Country [8] 0 0
United States of America
State/province [8] 0 0
Georgia
Country [9] 0 0
United States of America
State/province [9] 0 0
Idaho
Country [10] 0 0
United States of America
State/province [10] 0 0
Illinois
Country [11] 0 0
United States of America
State/province [11] 0 0
Indiana
Country [12] 0 0
United States of America
State/province [12] 0 0
Kansas
Country [13] 0 0
United States of America
State/province [13] 0 0
Kentucky
Country [14] 0 0
United States of America
State/province [14] 0 0
Louisiana
Country [15] 0 0
United States of America
State/province [15] 0 0
Maine
Country [16] 0 0
United States of America
State/province [16] 0 0
Maryland
Country [17] 0 0
United States of America
State/province [17] 0 0
Massachusetts
Country [18] 0 0
United States of America
State/province [18] 0 0
Michigan
Country [19] 0 0
United States of America
State/province [19] 0 0
Minnesota
Country [20] 0 0
United States of America
State/province [20] 0 0
Missouri
Country [21] 0 0
United States of America
State/province [21] 0 0
Nebraska
Country [22] 0 0
United States of America
State/province [22] 0 0
Nevada
Country [23] 0 0
United States of America
State/province [23] 0 0
New Jersey
Country [24] 0 0
United States of America
State/province [24] 0 0
New York
Country [25] 0 0
United States of America
State/province [25] 0 0
North Carolina
Country [26] 0 0
United States of America
State/province [26] 0 0
North Dakota
Country [27] 0 0
United States of America
State/province [27] 0 0
Ohio
Country [28] 0 0
United States of America
State/province [28] 0 0
Oklahoma
Country [29] 0 0
United States of America
State/province [29] 0 0
Pennsylvania
Country [30] 0 0
United States of America
State/province [30] 0 0
South Carolina
Country [31] 0 0
United States of America
State/province [31] 0 0
South Dakota
Country [32] 0 0
United States of America
State/province [32] 0 0
Tennessee
Country [33] 0 0
United States of America
State/province [33] 0 0
Texas
Country [34] 0 0
United States of America
State/province [34] 0 0
Virginia
Country [35] 0 0
United States of America
State/province [35] 0 0
Washington
Country [36] 0 0
United States of America
State/province [36] 0 0
Wisconsin
Country [37] 0 0
Argentina
State/province [37] 0 0
Bahia Blanca
Country [38] 0 0
Argentina
State/province [38] 0 0
Buenos Aires
Country [39] 0 0
Argentina
State/province [39] 0 0
Caba
Country [40] 0 0
Argentina
State/province [40] 0 0
Ciudad Autonoma Buenos Aires
Country [41] 0 0
Argentina
State/province [41] 0 0
Ciudad Autonoma de Buenos Aires
Country [42] 0 0
Argentina
State/province [42] 0 0
Cordoba
Country [43] 0 0
Argentina
State/province [43] 0 0
Coronel Suarez
Country [44] 0 0
Argentina
State/province [44] 0 0
Florencio Varela
Country [45] 0 0
Argentina
State/province [45] 0 0
La Plata
Country [46] 0 0
Argentina
State/province [46] 0 0
Mar del Plata
Country [47] 0 0
Argentina
State/province [47] 0 0
Quilmes
Country [48] 0 0
Argentina
State/province [48] 0 0
Rosario
Country [49] 0 0
Argentina
State/province [49] 0 0
Salta
Country [50] 0 0
Argentina
State/province [50] 0 0
San Martin
Country [51] 0 0
Argentina
State/province [51] 0 0
San Miguel de Tucuman
Country [52] 0 0
Argentina
State/province [52] 0 0
San Nicolas
Country [53] 0 0
Argentina
State/province [53] 0 0
Santa Fe
Country [54] 0 0
Argentina
State/province [54] 0 0
Venado Tuerto
Country [55] 0 0
Argentina
State/province [55] 0 0
Villa Maria
Country [56] 0 0
Austria
State/province [56] 0 0
Braunau am Inn
Country [57] 0 0
Austria
State/province [57] 0 0
Feldkirch
Country [58] 0 0
Austria
State/province [58] 0 0
Graz
Country [59] 0 0
Austria
State/province [59] 0 0
Linz
Country [60] 0 0
Belgium
State/province [60] 0 0
Bonheiden
Country [61] 0 0
Belgium
State/province [61] 0 0
Brasschaat
Country [62] 0 0
Belgium
State/province [62] 0 0
Brugge
Country [63] 0 0
Belgium
State/province [63] 0 0
Brussels
Country [64] 0 0
Belgium
State/province [64] 0 0
Bruxelles
Country [65] 0 0
Belgium
State/province [65] 0 0
Genk
Country [66] 0 0
Belgium
State/province [66] 0 0
Gent
Country [67] 0 0
Belgium
State/province [67] 0 0
Hasselt
Country [68] 0 0
Belgium
State/province [68] 0 0
Liege
Country [69] 0 0
Belgium
State/province [69] 0 0
Mechelen
Country [70] 0 0
Belgium
State/province [70] 0 0
Mol
Country [71] 0 0
Belgium
State/province [71] 0 0
Mons
Country [72] 0 0
Belgium
State/province [72] 0 0
Roeselare
Country [73] 0 0
Belgium
State/province [73] 0 0
Turnhout
Country [74] 0 0
Brazil
State/province [74] 0 0
Belo Horizonte
Country [75] 0 0
Brazil
State/province [75] 0 0
Botucatu
Country [76] 0 0
Brazil
State/province [76] 0 0
Brasilia
Country [77] 0 0
Brazil
State/province [77] 0 0
Campina Grande Do Sul
Country [78] 0 0
Brazil
State/province [78] 0 0
Campinas
Country [79] 0 0
Brazil
State/province [79] 0 0
Criciúma
Country [80] 0 0
Brazil
State/province [80] 0 0
Curitiba
Country [81] 0 0
Brazil
State/province [81] 0 0
Goiania
Country [82] 0 0
Brazil
State/province [82] 0 0
Marilia
Country [83] 0 0
Brazil
State/province [83] 0 0
Natal
Country [84] 0 0
Brazil
State/province [84] 0 0
Passo Fundo
Country [85] 0 0
Brazil
State/province [85] 0 0
Pelotas
Country [86] 0 0
Brazil
State/province [86] 0 0
Porto Alegre
Country [87] 0 0
Brazil
State/province [87] 0 0
Poços de Caldas
Country [88] 0 0
Brazil
State/province [88] 0 0
Recife
Country [89] 0 0
Brazil
State/province [89] 0 0
Ribeirao Preto
Country [90] 0 0
Brazil
State/province [90] 0 0
Rio de Janeiro
Country [91] 0 0
Brazil
State/province [91] 0 0
Salvador
Country [92] 0 0
Brazil
State/province [92] 0 0
Santo Andre
Country [93] 0 0
Brazil
State/province [93] 0 0
Sao Bernardo Do Campo
Country [94] 0 0
Brazil
State/province [94] 0 0
Sao Jose do Rio Preto
Country [95] 0 0
Brazil
State/province [95] 0 0
Sao Paulo
Country [96] 0 0
Brazil
State/province [96] 0 0
São José
Country [97] 0 0
Brazil
State/province [97] 0 0
Tatuí
Country [98] 0 0
Brazil
State/province [98] 0 0
Uberaba
Country [99] 0 0
Brazil
State/province [99] 0 0
Vitoria
Country [100] 0 0
Brazil
State/province [100] 0 0
Vitória
Country [101] 0 0
Brazil
State/province [101] 0 0
Votuporanga
Country [102] 0 0
Bulgaria
State/province [102] 0 0
Blagoevgrad
Country [103] 0 0
Bulgaria
State/province [103] 0 0
Burgas
Country [104] 0 0
Bulgaria
State/province [104] 0 0
Gabrovo
Country [105] 0 0
Bulgaria
State/province [105] 0 0
Haskovo
Country [106] 0 0
Bulgaria
State/province [106] 0 0
Panagyurishte
Country [107] 0 0
Bulgaria
State/province [107] 0 0
Pernik
Country [108] 0 0
Bulgaria
State/province [108] 0 0
Pleven
Country [109] 0 0
Bulgaria
State/province [109] 0 0
Plovdiv
Country [110] 0 0
Bulgaria
State/province [110] 0 0
Sofia
Country [111] 0 0
Bulgaria
State/province [111] 0 0
Stara Zagora
Country [112] 0 0
Canada
State/province [112] 0 0
Alberta
Country [113] 0 0
Canada
State/province [113] 0 0
British Columbia
Country [114] 0 0
Canada
State/province [114] 0 0
Nova Scotia
Country [115] 0 0
Canada
State/province [115] 0 0
Ontario
Country [116] 0 0
Canada
State/province [116] 0 0
Quebec
Country [117] 0 0
Canada
State/province [117] 0 0
Saskatchewan
Country [118] 0 0
Chile
State/province [118] 0 0
Puerto Varas
Country [119] 0 0
Chile
State/province [119] 0 0
Santiago
Country [120] 0 0
Chile
State/province [120] 0 0
Temuco
Country [121] 0 0
Chile
State/province [121] 0 0
Vina del Mar
Country [122] 0 0
China
State/province [122] 0 0
Baotou
Country [123] 0 0
China
State/province [123] 0 0
Beijing
Country [124] 0 0
China
State/province [124] 0 0
Changchun
Country [125] 0 0
China
State/province [125] 0 0
Changzhou
Country [126] 0 0
China
State/province [126] 0 0
Chengdu
Country [127] 0 0
China
State/province [127] 0 0
Chongqing
Country [128] 0 0
China
State/province [128] 0 0
Dongguan
Country [129] 0 0
China
State/province [129] 0 0
Fuzhou
Country [130] 0 0
China
State/province [130] 0 0
Guangzhou
Country [131] 0 0
China
State/province [131] 0 0
Guiyang
Country [132] 0 0
China
State/province [132] 0 0
Hangzhou
Country [133] 0 0
China
State/province [133] 0 0
Hefei
Country [134] 0 0
China
State/province [134] 0 0
Huizhou
Country [135] 0 0
China
State/province [135] 0 0
Jinan
Country [136] 0 0
China
State/province [136] 0 0
Jining
Country [137] 0 0
China
State/province [137] 0 0
Lanzhou
Country [138] 0 0
China
State/province [138] 0 0
Linfen
Country [139] 0 0
China
State/province [139] 0 0
Nanchang
Country [140] 0 0
China
State/province [140] 0 0
Nanjing
Country [141] 0 0
China
State/province [141] 0 0
Nanyang
Country [142] 0 0
China
State/province [142] 0 0
Ningbo
Country [143] 0 0
China
State/province [143] 0 0
Shanghai
Country [144] 0 0
China
State/province [144] 0 0
Shantou
Country [145] 0 0
China
State/province [145] 0 0
Shenzhen
Country [146] 0 0
China
State/province [146] 0 0
Su Zhou
Country [147] 0 0
China
State/province [147] 0 0
Suzhou
Country [148] 0 0
China
State/province [148] 0 0
Taiyuan
Country [149] 0 0
China
State/province [149] 0 0
Tianjin
Country [150] 0 0
China
State/province [150] 0 0
Wenzhou
Country [151] 0 0
China
State/province [151] 0 0
Wuhan
Country [152] 0 0
China
State/province [152] 0 0
Wuxi
Country [153] 0 0
China
State/province [153] 0 0
Xian
Country [154] 0 0
China
State/province [154] 0 0
Xinxiang
Country [155] 0 0
China
State/province [155] 0 0
Xuzhou
Country [156] 0 0
China
State/province [156] 0 0
Yanji
Country [157] 0 0
China
State/province [157] 0 0
Yichang
Country [158] 0 0
China
State/province [158] 0 0
Yinchuan
Country [159] 0 0
China
State/province [159] 0 0
Zhanjiang
Country [160] 0 0
China
State/province [160] 0 0
Zhengzhou
Country [161] 0 0
China
State/province [161] 0 0
Zhongshan
Country [162] 0 0
China
State/province [162] 0 0
Zunyi
Country [163] 0 0
Croatia
State/province [163] 0 0
Dubrovnik
Country [164] 0 0
Croatia
State/province [164] 0 0
Krapinske Toplice
Country [165] 0 0
Croatia
State/province [165] 0 0
Rijeka
Country [166] 0 0
Croatia
State/province [166] 0 0
Slavonski Brod
Country [167] 0 0
Croatia
State/province [167] 0 0
Zagreb
Country [168] 0 0
Czechia
State/province [168] 0 0
Brno
Country [169] 0 0
Czechia
State/province [169] 0 0
Ceske Budejovice
Country [170] 0 0
Czechia
State/province [170] 0 0
Hradec Kralove
Country [171] 0 0
Czechia
State/province [171] 0 0
Jihlava
Country [172] 0 0
Czechia
State/province [172] 0 0
Kolin
Country [173] 0 0
Czechia
State/province [173] 0 0
Liberec
Country [174] 0 0
Czechia
State/province [174] 0 0
Ostrava-Poruba
Country [175] 0 0
Czechia
State/province [175] 0 0
Pardubice
Country [176] 0 0
Czechia
State/province [176] 0 0
Plzen
Country [177] 0 0
Czechia
State/province [177] 0 0
Prague
Country [178] 0 0
Czechia
State/province [178] 0 0
Praha 10
Country [179] 0 0
Czechia
State/province [179] 0 0
Praha 2
Country [180] 0 0
Czechia
State/province [180] 0 0
Praha 4
Country [181] 0 0
Czechia
State/province [181] 0 0
Slany
Country [182] 0 0
Czechia
State/province [182] 0 0
Trinec
Country [183] 0 0
Denmark
State/province [183] 0 0
Aahus N
Country [184] 0 0
Denmark
State/province [184] 0 0
Copenhagen S
Country [185] 0 0
Denmark
State/province [185] 0 0
Frederiksberg
Country [186] 0 0
Denmark
State/province [186] 0 0
Herning
Country [187] 0 0
Denmark
State/province [187] 0 0
Holbæk
Country [188] 0 0
Denmark
State/province [188] 0 0
Hvidovre
Country [189] 0 0
Denmark
State/province [189] 0 0
Slagelse
Country [190] 0 0
Denmark
State/province [190] 0 0
Svendborg
Country [191] 0 0
Denmark
State/province [191] 0 0
Viborg
Country [192] 0 0
France
State/province [192] 0 0
Angers
Country [193] 0 0
France
State/province [193] 0 0
Chambray Les Tours
Country [194] 0 0
France
State/province [194] 0 0
Corbeil Essonnes cedex
Country [195] 0 0
France
State/province [195] 0 0
Creteil
Country [196] 0 0
France
State/province [196] 0 0
Dijon cedex
Country [197] 0 0
France
State/province [197] 0 0
La Tronche
Country [198] 0 0
France
State/province [198] 0 0
Le Coudray
Country [199] 0 0
France
State/province [199] 0 0
Lille Cedex
Country [200] 0 0
France
State/province [200] 0 0
Lyon
Country [201] 0 0
France
State/province [201] 0 0
Montauban
Country [202] 0 0
France
State/province [202] 0 0
Montpellier
Country [203] 0 0
France
State/province [203] 0 0
Mulhouse Cedex
Country [204] 0 0
France
State/province [204] 0 0
Nantes Cedex 1
Country [205] 0 0
France
State/province [205] 0 0
Nice Cedex 1
Country [206] 0 0
France
State/province [206] 0 0
Nîmes Cedex 9
Country [207] 0 0
France
State/province [207] 0 0
Paris cedex 14
Country [208] 0 0
France
State/province [208] 0 0
Paris
Country [209] 0 0
France
State/province [209] 0 0
Pau Cedex
Country [210] 0 0
France
State/province [210] 0 0
Pessac
Country [211] 0 0
France
State/province [211] 0 0
Poitiers
Country [212] 0 0
France
State/province [212] 0 0
Potigny
Country [213] 0 0
France
State/province [213] 0 0
Rouen cedex
Country [214] 0 0
France
State/province [214] 0 0
Rouen
Country [215] 0 0
France
State/province [215] 0 0
Strasbourg
Country [216] 0 0
France
State/province [216] 0 0
Toulouse Cedex 9
Country [217] 0 0
France
State/province [217] 0 0
Vandoeuvre les Nancy Cedex
Country [218] 0 0
France
State/province [218] 0 0
Versailles Cedex
Country [219] 0 0
Germany
State/province [219] 0 0
Bad Friedrichshall
Country [220] 0 0
Germany
State/province [220] 0 0
Bad Krozingen
Country [221] 0 0
Germany
State/province [221] 0 0
Bad Nauheim
Country [222] 0 0
Germany
State/province [222] 0 0
Berlin
Country [223] 0 0
Germany
State/province [223] 0 0
Bielefeld
Country [224] 0 0
Germany
State/province [224] 0 0
Bitburg
Country [225] 0 0
Germany
State/province [225] 0 0
Bonn-Beuel
Country [226] 0 0
Germany
State/province [226] 0 0
Bonn
Country [227] 0 0
Germany
State/province [227] 0 0
Brandenburg an der Havel
Country [228] 0 0
Germany
State/province [228] 0 0
Bremen
Country [229] 0 0
Germany
State/province [229] 0 0
Dortmund
Country [230] 0 0
Germany
State/province [230] 0 0
Dresden
Country [231] 0 0
Germany
State/province [231] 0 0
Erfurt
Country [232] 0 0
Germany
State/province [232] 0 0
Frankfurt
Country [233] 0 0
Germany
State/province [233] 0 0
Greifswald
Country [234] 0 0
Germany
State/province [234] 0 0
Hamburg
Country [235] 0 0
Germany
State/province [235] 0 0
Leverkusen
Country [236] 0 0
Germany
State/province [236] 0 0
Ludwigshafen
Country [237] 0 0
Germany
State/province [237] 0 0
Luedenscheid
Country [238] 0 0
Germany
State/province [238] 0 0
Magdeburg
Country [239] 0 0
Germany
State/province [239] 0 0
Mainz
Country [240] 0 0
Germany
State/province [240] 0 0
Mannheim
Country [241] 0 0
Germany
State/province [241] 0 0
Moenchengladbach
Country [242] 0 0
Germany
State/province [242] 0 0
Neuwied
Country [243] 0 0
Germany
State/province [243] 0 0
Remscheid
Country [244] 0 0
Germany
State/province [244] 0 0
Rostock
Country [245] 0 0
Germany
State/province [245] 0 0
Worms
Country [246] 0 0
Greece
State/province [246] 0 0
Alexandroupolis
Country [247] 0 0
Greece
State/province [247] 0 0
Athens
Country [248] 0 0
Greece
State/province [248] 0 0
Heraklion
Country [249] 0 0
Greece
State/province [249] 0 0
Ioannina
Country [250] 0 0
Greece
State/province [250] 0 0
Larissa
Country [251] 0 0
Greece
State/province [251] 0 0
Patra
Country [252] 0 0
Greece
State/province [252] 0 0
Thessaloniki
Country [253] 0 0
Hungary
State/province [253] 0 0
Budapest
Country [254] 0 0
Hungary
State/province [254] 0 0
Debrecen
Country [255] 0 0
Hungary
State/province [255] 0 0
Kaposvar
Country [256] 0 0
Hungary
State/province [256] 0 0
Kecskemet
Country [257] 0 0
Hungary
State/province [257] 0 0
Pecs
Country [258] 0 0
Hungary
State/province [258] 0 0
Szeged
Country [259] 0 0
Hungary
State/province [259] 0 0
Szekszárd
Country [260] 0 0
Hungary
State/province [260] 0 0
Szolnok
Country [261] 0 0
Hungary
State/province [261] 0 0
Szombathely
Country [262] 0 0
Hungary
State/province [262] 0 0
Zalaegerszeg
Country [263] 0 0
India
State/province [263] 0 0
Ahmedabad
Country [264] 0 0
India
State/province [264] 0 0
Aligarh
Country [265] 0 0
India
State/province [265] 0 0
Bangalore
Country [266] 0 0
India
State/province [266] 0 0
Belgaum
Country [267] 0 0
India
State/province [267] 0 0
Bikaner
Country [268] 0 0
India
State/province [268] 0 0
Chennai
Country [269] 0 0
India
State/province [269] 0 0
Cochin
Country [270] 0 0
India
State/province [270] 0 0
Delhi
Country [271] 0 0
India
State/province [271] 0 0
Hyderabad
Country [272] 0 0
India
State/province [272] 0 0
Hyderbad
Country [273] 0 0
India
State/province [273] 0 0
Kolkata
Country [274] 0 0
India
State/province [274] 0 0
Ludhiana
Country [275] 0 0
India
State/province [275] 0 0
Mangalore
Country [276] 0 0
India
State/province [276] 0 0
Mumbai
Country [277] 0 0
India
State/province [277] 0 0
Nagpur
Country [278] 0 0
India
State/province [278] 0 0
New Delhi
Country [279] 0 0
India
State/province [279] 0 0
Pune
Country [280] 0 0
India
State/province [280] 0 0
Shimoga
Country [281] 0 0
India
State/province [281] 0 0
Surat
Country [282] 0 0
India
State/province [282] 0 0
Vijayawada
Country [283] 0 0
India
State/province [283] 0 0
Vishakhapatnam
Country [284] 0 0
Israel
State/province [284] 0 0
Afula
Country [285] 0 0
Israel
State/province [285] 0 0
Ashdod
Country [286] 0 0
Israel
State/province [286] 0 0
Ashkelon
Country [287] 0 0
Israel
State/province [287] 0 0
Beersheba
Country [288] 0 0
Israel
State/province [288] 0 0
Haifa
Country [289] 0 0
Israel
State/province [289] 0 0
Holon
Country [290] 0 0
Israel
State/province [290] 0 0
Jerusalem
Country [291] 0 0
Israel
State/province [291] 0 0
Kfar Sava
Country [292] 0 0
Israel
State/province [292] 0 0
Naharya
Country [293] 0 0
Israel
State/province [293] 0 0
Petah Tikva
Country [294] 0 0
Israel
State/province [294] 0 0
Ramat Gan
Country [295] 0 0
Israel
State/province [295] 0 0
Rechovot
Country [296] 0 0
Israel
State/province [296] 0 0
Rishon Lezion
Country [297] 0 0
Israel
State/province [297] 0 0
Safed
Country [298] 0 0
Israel
State/province [298] 0 0
Tiberias
Country [299] 0 0
Italy
State/province [299] 0 0
Alessandria
Country [300] 0 0
Italy
State/province [300] 0 0
Bergamo
Country [301] 0 0
Italy
State/province [301] 0 0
Bologna
Country [302] 0 0
Italy
State/province [302] 0 0
Chieti
Country [303] 0 0
Italy
State/province [303] 0 0
Ferrara
Country [304] 0 0
Italy
State/province [304] 0 0
La Spezia
Country [305] 0 0
Italy
State/province [305] 0 0
Mestre
Country [306] 0 0
Italy
State/province [306] 0 0
Milano
Country [307] 0 0
Italy
State/province [307] 0 0
Napoli
Country [308] 0 0
Italy
State/province [308] 0 0
Parma
Country [309] 0 0
Italy
State/province [309] 0 0
Pavia
Country [310] 0 0
Italy
State/province [310] 0 0
Pisa
Country [311] 0 0
Italy
State/province [311] 0 0
Roma
Country [312] 0 0
Italy
State/province [312] 0 0
Rozzano
Country [313] 0 0
Italy
State/province [313] 0 0
Sassari
Country [314] 0 0
Italy
State/province [314] 0 0
Seriate
Country [315] 0 0
Italy
State/province [315] 0 0
Sesto San Giovanni
Country [316] 0 0
Italy
State/province [316] 0 0
Torrette Di Ancona
Country [317] 0 0
Italy
State/province [317] 0 0
Treviglio
Country [318] 0 0
Japan
State/province [318] 0 0
Aichi
Country [319] 0 0
Japan
State/province [319] 0 0
Amagasaki shi
Country [320] 0 0
Japan
State/province [320] 0 0
Chiba
Country [321] 0 0
Japan
State/province [321] 0 0
Chikushino-shi
Country [322] 0 0
Japan
State/province [322] 0 0
Fukui-shi
Country [323] 0 0
Japan
State/province [323] 0 0
Fukuoka-shi
Country [324] 0 0
Japan
State/province [324] 0 0
Fukuoka
Country [325] 0 0
Japan
State/province [325] 0 0
Gifu
Country [326] 0 0
Japan
State/province [326] 0 0
Gunma
Country [327] 0 0
Japan
State/province [327] 0 0
Himeji-shi
Country [328] 0 0
Japan
State/province [328] 0 0
Hiratsuka-shi
Country [329] 0 0
Japan
State/province [329] 0 0
Hirosaki
Country [330] 0 0
Japan
State/province [330] 0 0
Hiroshima
Country [331] 0 0
Japan
State/province [331] 0 0
Isehara
Country [332] 0 0
Japan
State/province [332] 0 0
Ishikawa
Country [333] 0 0
Japan
State/province [333] 0 0
Itabashi Ku
Country [334] 0 0
Japan
State/province [334] 0 0
Izunokuni-shi
Country [335] 0 0
Japan
State/province [335] 0 0
Kamogawa
Country [336] 0 0
Japan
State/province [336] 0 0
Kanagawa
Country [337] 0 0
Japan
State/province [337] 0 0
Kanazawa-shi
Country [338] 0 0
Japan
State/province [338] 0 0
Kasuga-shi
Country [339] 0 0
Japan
State/province [339] 0 0
Kisarazu-shi
Country [340] 0 0
Japan
State/province [340] 0 0
Kitakyushu-shi
Country [341] 0 0
Japan
State/province [341] 0 0
Kochi
Country [342] 0 0
Japan
State/province [342] 0 0
Koga
Country [343] 0 0
Japan
State/province [343] 0 0
Kumamoto-shi
Country [344] 0 0
Japan
State/province [344] 0 0
Kurashiki
Country [345] 0 0
Japan
State/province [345] 0 0
Kure-shi
Country [346] 0 0
Japan
State/province [346] 0 0
Kyoto-shi
Country [347] 0 0
Japan
State/province [347] 0 0
Kyoto
Country [348] 0 0
Japan
State/province [348] 0 0
Matsudo-shi
Country [349] 0 0
Japan
State/province [349] 0 0
Matsumoto-shi
Country [350] 0 0
Japan
State/province [350] 0 0
Meguro-ku
Country [351] 0 0
Japan
State/province [351] 0 0
Minato-ku
Country [352] 0 0
Japan
State/province [352] 0 0
Miyazaki-shi
Country [353] 0 0
Japan
State/province [353] 0 0
Nagoya-shi
Country [354] 0 0
Japan
State/province [354] 0 0
Nishinomiya-shi
Country [355] 0 0
Japan
State/province [355] 0 0
Okayama shi
Country [356] 0 0
Japan
State/province [356] 0 0
Osaka-shi
Country [357] 0 0
Japan
State/province [357] 0 0
Osaka
Country [358] 0 0
Japan
State/province [358] 0 0
Sagamihara
Country [359] 0 0
Japan
State/province [359] 0 0
Saga
Country [360] 0 0
Japan
State/province [360] 0 0
Saitama-shi
Country [361] 0 0
Japan
State/province [361] 0 0
Saitama
Country [362] 0 0
Japan
State/province [362] 0 0
Sendai
Country [363] 0 0
Japan
State/province [363] 0 0
Shinagawa
Country [364] 0 0
Japan
State/province [364] 0 0
Shinjuku-ku
Country [365] 0 0
Japan
State/province [365] 0 0
Shiwa-gun
Country [366] 0 0
Japan
State/province [366] 0 0
Suita-Shi
Country [367] 0 0
Japan
State/province [367] 0 0
Takamatsu
Country [368] 0 0
Japan
State/province [368] 0 0
Tokushima
Country [369] 0 0
Japan
State/province [369] 0 0
Tokyo
Country [370] 0 0
Japan
State/province [370] 0 0
Toyama-shi
Country [371] 0 0
Japan
State/province [371] 0 0
Tsuchiura-City
Country [372] 0 0
Japan
State/province [372] 0 0
Tsukuba shi
Country [373] 0 0
Japan
State/province [373] 0 0
Tsu
Country [374] 0 0
Japan
State/province [374] 0 0
Ube
Country [375] 0 0
Japan
State/province [375] 0 0
Urayasu-shi
Country [376] 0 0
Japan
State/province [376] 0 0
Ureshino-shi
Country [377] 0 0
Japan
State/province [377] 0 0
Wakayama
Country [378] 0 0
Japan
State/province [378] 0 0
Yokohama
Country [379] 0 0
Korea, Republic of
State/province [379] 0 0
Bucheon-si
Country [380] 0 0
Korea, Republic of
State/province [380] 0 0
Busan
Country [381] 0 0
Korea, Republic of
State/province [381] 0 0
Cheongju-si
Country [382] 0 0
Korea, Republic of
State/province [382] 0 0
Chuncheon
Country [383] 0 0
Korea, Republic of
State/province [383] 0 0
Daegu
Country [384] 0 0
Korea, Republic of
State/province [384] 0 0
Daejeon
Country [385] 0 0
Korea, Republic of
State/province [385] 0 0
Gangseo-gu
Country [386] 0 0
Korea, Republic of
State/province [386] 0 0
Goyang-si
Country [387] 0 0
Korea, Republic of
State/province [387] 0 0
Gwangju
Country [388] 0 0
Korea, Republic of
State/province [388] 0 0
Gyeonggi Do
Country [389] 0 0
Korea, Republic of
State/province [389] 0 0
Incheon
Country [390] 0 0
Korea, Republic of
State/province [390] 0 0
Sejong-si
Country [391] 0 0
Korea, Republic of
State/province [391] 0 0
Seoul
Country [392] 0 0
Korea, Republic of
State/province [392] 0 0
Wonju
Country [393] 0 0
Korea, Republic of
State/province [393] 0 0
Yangsan Si
Country [394] 0 0
Latvia
State/province [394] 0 0
Daugavpils
Country [395] 0 0
Latvia
State/province [395] 0 0
Riga
Country [396] 0 0
Lithuania
State/province [396] 0 0
Kaunas
Country [397] 0 0
Lithuania
State/province [397] 0 0
Klaipeda
Country [398] 0 0
Lithuania
State/province [398] 0 0
Vilnius
Country [399] 0 0
Malaysia
State/province [399] 0 0
Kota Bahru
Country [400] 0 0
Malaysia
State/province [400] 0 0
Kota Bharu
Country [401] 0 0
Malaysia
State/province [401] 0 0
Kota Kinabalu
Country [402] 0 0
Malaysia
State/province [402] 0 0
Kuala Lumpur
Country [403] 0 0
Malaysia
State/province [403] 0 0
Kuching
Country [404] 0 0
Malaysia
State/province [404] 0 0
Miri
Country [405] 0 0
Malaysia
State/province [405] 0 0
Pulau Pinang
Country [406] 0 0
Malaysia
State/province [406] 0 0
Seberang Jaya
Country [407] 0 0
Malaysia
State/province [407] 0 0
Selayang
Country [408] 0 0
Mexico
State/province [408] 0 0
Aguascalientes
Country [409] 0 0
Mexico
State/province [409] 0 0
Culiacan
Country [410] 0 0
Mexico
State/province [410] 0 0
Mazatlan
Country [411] 0 0
Mexico
State/province [411] 0 0
Mexico
Country [412] 0 0
Mexico
State/province [412] 0 0
Monterrey
Country [413] 0 0
Mexico
State/province [413] 0 0
Queretaro
Country [414] 0 0
Mexico
State/province [414] 0 0
San Luis Potosí
Country [415] 0 0
Mexico
State/province [415] 0 0
Tijuana
Country [416] 0 0
Mexico
State/province [416] 0 0
Torreon
Country [417] 0 0
Mexico
State/province [417] 0 0
Xalapa
Country [418] 0 0
Netherlands
State/province [418] 0 0
Alkmaar
Country [419] 0 0
Netherlands
State/province [419] 0 0
Almelo
Country [420] 0 0
Netherlands
State/province [420] 0 0
Amersfoort
Country [421] 0 0
Netherlands
State/province [421] 0 0
Amsterdam
Country [422] 0 0
Netherlands
State/province [422] 0 0
Deventer
Country [423] 0 0
Netherlands
State/province [423] 0 0
Ede
Country [424] 0 0
Netherlands
State/province [424] 0 0
Eindhoven
Country [425] 0 0
Netherlands
State/province [425] 0 0
Emmen
Country [426] 0 0
Netherlands
State/province [426] 0 0
Enschede
Country [427] 0 0
Netherlands
State/province [427] 0 0
Goes
Country [428] 0 0
Netherlands
State/province [428] 0 0
Gouda
Country [429] 0 0
Netherlands
State/province [429] 0 0
Harderwijk
Country [430] 0 0
Netherlands
State/province [430] 0 0
Heerlen
Country [431] 0 0
Netherlands
State/province [431] 0 0
Helmond
Country [432] 0 0
Netherlands
State/province [432] 0 0
Leiderdorp
Country [433] 0 0
Netherlands
State/province [433] 0 0
Maastricht
Country [434] 0 0
Netherlands
State/province [434] 0 0
Nieuwegein
Country [435] 0 0
Netherlands
State/province [435] 0 0
Nijmegen
Country [436] 0 0
Netherlands
State/province [436] 0 0
Roosendaal
Country [437] 0 0
Netherlands
State/province [437] 0 0
Rotterdam
Country [438] 0 0
Netherlands
State/province [438] 0 0
s-Hertogenbosch
Country [439] 0 0
Netherlands
State/province [439] 0 0
Sneek
Country [440] 0 0
Netherlands
State/province [440] 0 0
Tiel
Country [441] 0 0
Netherlands
State/province [441] 0 0
Utrecht
Country [442] 0 0
Netherlands
State/province [442] 0 0
Veldhoven
Country [443] 0 0
Netherlands
State/province [443] 0 0
Venlo
Country [444] 0 0
Netherlands
State/province [444] 0 0
Zutphen
Country [445] 0 0
New Zealand
State/province [445] 0 0
Auckland
Country [446] 0 0
New Zealand
State/province [446] 0 0
Christchurch
Country [447] 0 0
New Zealand
State/province [447] 0 0
Dunedin
Country [448] 0 0
New Zealand
State/province [448] 0 0
Hastings
Country [449] 0 0
New Zealand
State/province [449] 0 0
New Plymouth
Country [450] 0 0
New Zealand
State/province [450] 0 0
Otahuhu
Country [451] 0 0
New Zealand
State/province [451] 0 0
Rotorua
Country [452] 0 0
New Zealand
State/province [452] 0 0
Tauranga
Country [453] 0 0
New Zealand
State/province [453] 0 0
Whangarei
Country [454] 0 0
North Macedonia
State/province [454] 0 0
Skopje
Country [455] 0 0
North Macedonia
State/province [455] 0 0
Tetovo
Country [456] 0 0
Philippines
State/province [456] 0 0
Angeles
Country [457] 0 0
Philippines
State/province [457] 0 0
Cavite
Country [458] 0 0
Philippines
State/province [458] 0 0
Davao City
Country [459] 0 0
Philippines
State/province [459] 0 0
Davao
Country [460] 0 0
Philippines
State/province [460] 0 0
Iloilo
Country [461] 0 0
Philippines
State/province [461] 0 0
Lipa City
Country [462] 0 0
Philippines
State/province [462] 0 0
Mandaluyong
Country [463] 0 0
Philippines
State/province [463] 0 0
Manila
Country [464] 0 0
Philippines
State/province [464] 0 0
Marikina City
Country [465] 0 0
Poland
State/province [465] 0 0
Bialystok
Country [466] 0 0
Poland
State/province [466] 0 0
Bydgoszcz
Country [467] 0 0
Poland
State/province [467] 0 0
Bytom
Country [468] 0 0
Poland
State/province [468] 0 0
Elblag
Country [469] 0 0
Poland
State/province [469] 0 0
Katowice
Country [470] 0 0
Poland
State/province [470] 0 0
Kielce
Country [471] 0 0
Poland
State/province [471] 0 0
Krakow
Country [472] 0 0
Poland
State/province [472] 0 0
Lodz
Country [473] 0 0
Poland
State/province [473] 0 0
Lublin
Country [474] 0 0
Poland
State/province [474] 0 0
Naleczow
Country [475] 0 0
Poland
State/province [475] 0 0
Olsztyn
Country [476] 0 0
Poland
State/province [476] 0 0
Oswiecim
Country [477] 0 0
Poland
State/province [477] 0 0
Poznan
Country [478] 0 0
Poland
State/province [478] 0 0
Przemysl
Country [479] 0 0
Poland
State/province [479] 0 0
Siedlce
Country [480] 0 0
Poland
State/province [480] 0 0
Skierniewice
Country [481] 0 0
Poland
State/province [481] 0 0
Sopot
Country [482] 0 0
Poland
State/province [482] 0 0
Torun
Country [483] 0 0
Poland
State/province [483] 0 0
Warszawa
Country [484] 0 0
Poland
State/province [484] 0 0
Walbrzych
Country [485] 0 0
Poland
State/province [485] 0 0
Wroclaw
Country [486] 0 0
Portugal
State/province [486] 0 0
Aveiro
Country [487] 0 0
Portugal
State/province [487] 0 0
Braga
Country [488] 0 0
Portugal
State/province [488] 0 0
Coimbra
Country [489] 0 0
Portugal
State/province [489] 0 0
Covilha
Country [490] 0 0
Portugal
State/province [490] 0 0
Guimaraes
Country [491] 0 0
Portugal
State/province [491] 0 0
Leiria
Country [492] 0 0
Portugal
State/province [492] 0 0
Lisboa
Country [493] 0 0
Portugal
State/province [493] 0 0
Lisbon
Country [494] 0 0
Portugal
State/province [494] 0 0
Santa Maria da Feira
Country [495] 0 0
Portugal
State/province [495] 0 0
Vila Nova de Gaia
Country [496] 0 0
Portugal
State/province [496] 0 0
Vila Real
Country [497] 0 0
Romania
State/province [497] 0 0
Baia-Mare
Country [498] 0 0
Romania
State/province [498] 0 0
Brasov
Country [499] 0 0
Romania
State/province [499] 0 0
Bucharest
Country [500] 0 0
Romania
State/province [500] 0 0
Bucuresti
Country [501] 0 0
Romania
State/province [501] 0 0
Cluj-Napoca
Country [502] 0 0
Romania
State/province [502] 0 0
Constanta
Country [503] 0 0
Romania
State/province [503] 0 0
Craiova
Country [504] 0 0
Romania
State/province [504] 0 0
Iasi
Country [505] 0 0
Romania
State/province [505] 0 0
Oradea
Country [506] 0 0
Romania
State/province [506] 0 0
Pitesti
Country [507] 0 0
Romania
State/province [507] 0 0
Targu-Mures
Country [508] 0 0
Romania
State/province [508] 0 0
Tg. Mures
Country [509] 0 0
Romania
State/province [509] 0 0
Timisoara
Country [510] 0 0
Serbia
State/province [510] 0 0
Belgrade
Country [511] 0 0
Serbia
State/province [511] 0 0
Kragujevac
Country [512] 0 0
Serbia
State/province [512] 0 0
Niska Banja
Country [513] 0 0
Serbia
State/province [513] 0 0
Nis
Country [514] 0 0
Serbia
State/province [514] 0 0
Pancevo
Country [515] 0 0
Serbia
State/province [515] 0 0
Smederevo
Country [516] 0 0
Serbia
State/province [516] 0 0
Sremska Mitrovica
Country [517] 0 0
Serbia
State/province [517] 0 0
Zajecar
Country [518] 0 0
Singapore
State/province [518] 0 0
Singapore
Country [519] 0 0
Slovakia
State/province [519] 0 0
Banska Bystrica
Country [520] 0 0
Slovakia
State/province [520] 0 0
Bardejov
Country [521] 0 0
Slovakia
State/province [521] 0 0
Bratislava
Country [522] 0 0
Slovakia
State/province [522] 0 0
Brezno
Country [523] 0 0
Slovakia
State/province [523] 0 0
Kosice
Country [524] 0 0
Slovakia
State/province [524] 0 0
Košice
Country [525] 0 0
Slovakia
State/province [525] 0 0
Lucenec
Country [526] 0 0
Slovakia
State/province [526] 0 0
Martin
Country [527] 0 0
Slovakia
State/province [527] 0 0
Moldava nad Bodvou
Country [528] 0 0
Slovakia
State/province [528] 0 0
Nitra
Country [529] 0 0
Slovakia
State/province [529] 0 0
Nove Zamky
Country [530] 0 0
Slovakia
State/province [530] 0 0
Svidnik
Country [531] 0 0
Slovakia
State/province [531] 0 0
Zilina
Country [532] 0 0
Slovakia
State/province [532] 0 0
Zvolen
Country [533] 0 0
South Africa
State/province [533] 0 0
Cape Town
Country [534] 0 0
South Africa
State/province [534] 0 0
Centurion
Country [535] 0 0
South Africa
State/province [535] 0 0
Durban
Country [536] 0 0
South Africa
State/province [536] 0 0
Johannesburg
Country [537] 0 0
South Africa
State/province [537] 0 0
Mossel Bay
Country [538] 0 0
South Africa
State/province [538] 0 0
Somerset West
Country [539] 0 0
South Africa
State/province [539] 0 0
Worcester
Country [540] 0 0
Spain
State/province [540] 0 0
Alicante
Country [541] 0 0
Spain
State/province [541] 0 0
Barcelona
Country [542] 0 0
Spain
State/province [542] 0 0
El Palmar
Country [543] 0 0
Spain
State/province [543] 0 0
Gijon
Country [544] 0 0
Spain
State/province [544] 0 0
Lleida
Country [545] 0 0
Spain
State/province [545] 0 0
Madrid
Country [546] 0 0
Spain
State/province [546] 0 0
Malaga
Country [547] 0 0
Spain
State/province [547] 0 0
Manises
Country [548] 0 0
Spain
State/province [548] 0 0
Pamplona
Country [549] 0 0
Spain
State/province [549] 0 0
Santiago de Compostela
Country [550] 0 0
Spain
State/province [550] 0 0
Tarragona
Country [551] 0 0
Spain
State/province [551] 0 0
Valencia
Country [552] 0 0
Spain
State/province [552] 0 0
Vigo
Country [553] 0 0
Spain
State/province [553] 0 0
Zaragoza
Country [554] 0 0
Switzerland
State/province [554] 0 0
Basel
Country [555] 0 0
Switzerland
State/province [555] 0 0
Bern
Country [556] 0 0
Switzerland
State/province [556] 0 0
Geneve 14
Country [557] 0 0
Switzerland
State/province [557] 0 0
Lugano
Country [558] 0 0
Switzerland
State/province [558] 0 0
Zuerich
Country [559] 0 0
Taiwan
State/province [559] 0 0
Changhua
Country [560] 0 0
Taiwan
State/province [560] 0 0
Kaohsiung
Country [561] 0 0
Taiwan
State/province [561] 0 0
New Taipei
Country [562] 0 0
Taiwan
State/province [562] 0 0
Taichung
Country [563] 0 0
Taiwan
State/province [563] 0 0
Tainan
Country [564] 0 0
Taiwan
State/province [564] 0 0
Taipei City
Country [565] 0 0
Taiwan
State/province [565] 0 0
Taipei
Country [566] 0 0
Taiwan
State/province [566] 0 0
Taoyuan County
Country [567] 0 0
Taiwan
State/province [567] 0 0
Yilan County
Country [568] 0 0
Thailand
State/province [568] 0 0
Bangkoknoi
Country [569] 0 0
Thailand
State/province [569] 0 0
Bangkok
Country [570] 0 0
Thailand
State/province [570] 0 0
Chiangmai
Country [571] 0 0
Thailand
State/province [571] 0 0
Nai Mueang Subdistrict Mueang
Country [572] 0 0
Thailand
State/province [572] 0 0
Pathum Wan
Country [573] 0 0
Turkey
State/province [573] 0 0
Afyon
Country [574] 0 0
Turkey
State/province [574] 0 0
Ankara
Country [575] 0 0
Turkey
State/province [575] 0 0
Eskisehir
Country [576] 0 0
Turkey
State/province [576] 0 0
Istanbul
Country [577] 0 0
Turkey
State/province [577] 0 0
Izmir
Country [578] 0 0
Turkey
State/province [578] 0 0
Karabuk
Country [579] 0 0
Turkey
State/province [579] 0 0
Kayseri
Country [580] 0 0
Turkey
State/province [580] 0 0
Kutahya
Country [581] 0 0
Turkey
State/province [581] 0 0
Mersin
Country [582] 0 0
Turkey
State/province [582] 0 0
Samsun
Country [583] 0 0
United Kingdom
State/province [583] 0 0
Basingstoke
Country [584] 0 0
United Kingdom
State/province [584] 0 0
Bath
Country [585] 0 0
United Kingdom
State/province [585] 0 0
Birmingham
Country [586] 0 0
United Kingdom
State/province [586] 0 0
Bournemouth
Country [587] 0 0
United Kingdom
State/province [587] 0 0
Bristol
Country [588] 0 0
United Kingdom
State/province [588] 0 0
Dorchester
Country [589] 0 0
United Kingdom
State/province [589] 0 0
Dudley
Country [590] 0 0
United Kingdom
State/province [590] 0 0
East Kilbride
Country [591] 0 0
United Kingdom
State/province [591] 0 0
Edinburgh
Country [592] 0 0
United Kingdom
State/province [592] 0 0
Exeter
Country [593] 0 0
United Kingdom
State/province [593] 0 0
Hampstead
Country [594] 0 0
United Kingdom
State/province [594] 0 0
Harefield
Country [595] 0 0
United Kingdom
State/province [595] 0 0
Isleworth
Country [596] 0 0
United Kingdom
State/province [596] 0 0
Kingston upon Thames
Country [597] 0 0
United Kingdom
State/province [597] 0 0
Leeds
Country [598] 0 0
United Kingdom
State/province [598] 0 0
Lincoln
Country [599] 0 0
United Kingdom
State/province [599] 0 0
Londonderry
Country [600] 0 0
United Kingdom
State/province [600] 0 0
London
Country [601] 0 0
United Kingdom
State/province [601] 0 0
Manchester
Country [602] 0 0
United Kingdom
State/province [602] 0 0
Middlesbrough
Country [603] 0 0
United Kingdom
State/province [603] 0 0
Newcastle Upon Tyne
Country [604] 0 0
United Kingdom
State/province [604] 0 0
Peterborough
Country [605] 0 0
United Kingdom
State/province [605] 0 0
Plymouth
Country [606] 0 0
United Kingdom
State/province [606] 0 0
Portsmouth
Country [607] 0 0
United Kingdom
State/province [607] 0 0
Redhill
Country [608] 0 0
United Kingdom
State/province [608] 0 0
Stevenage
Country [609] 0 0
United Kingdom
State/province [609] 0 0
Swansea
Country [610] 0 0
United Kingdom
State/province [610] 0 0
Taunton
Country [611] 0 0
United Kingdom
State/province [611] 0 0
Torquay
Country [612] 0 0
United Kingdom
State/province [612] 0 0
West Bromwich
Country [613] 0 0
United Kingdom
State/province [613] 0 0
Wigan
Country [614] 0 0
United Kingdom
State/province [614] 0 0
Yeovil
Country [615] 0 0
Vietnam
State/province [615] 0 0
Hanoi
Country [616] 0 0
Vietnam
State/province [616] 0 0
Ho Chi Minh

Funding & Sponsors
Primary sponsor type
Commercial sector/industry
Name
Janssen Research & Development, LLC
Address
Country
Other collaborator category [1] 0 0
Commercial sector/industry
Name [1] 0 0
Bristol-Myers Squibb
Address [1] 0 0
Country [1] 0 0

Ethics approval
Ethics application status

Summary
Brief summary
Trial website
Trial related presentations / publications
Public notes

Contacts
Principal investigator
Name 0 0
Janssen Research & Development, LLC Clinical Trial
Address 0 0
Janssen Research & Development, LLC
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for public queries
Name 0 0
Study Contact
Address 0 0
Country 0 0
Phone 0 0
844-434-4210
Fax 0 0
Email 0 0
Participate-In-This-Study@its.jnj.com
Contact person for scientific queries

Data sharing statement
Will individual participant data (IPD) for this trial be available (including data dictionaries)?
Yes
What data in particular will be shared?
The data sharing policy of the Janssen Pharmaceutical Companies of Johnson \& Johnson is available at www.janssen.com/clinical-trials/transparency. As noted on this site, requests for access to the study data can be submitted through Yale Open Data Access (YODA) Project site at yoda.yale.edu
When will data be available (start and end dates)?
Available to whom?
Available for what types of analyses?
How or where can data be obtained?
IPD available at link: https://www.janssen.com/clinical-trials/transparency


What supporting documents are/will be available?

No Supporting Document Provided



Results publications and other study-related documents

No documents have been uploaded by study researchers.