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Trial details imported from

For full trial details, please see the original record at

Registration number
Ethics application status
Date submitted
Date registered
Date last updated

Titles & IDs
Public title
ETHOS ENGAGE: Enhancing Treatment of Hepatitis C in Opioid Substitution Settings
Scientific title
Enhancing Treatment of Hepatitis C in Opioid Substitution Settings II (ETHOS II): A Partnership Project to Enhance Hepatitis C Care in Drug and Alcohol Clinics
Secondary ID [1] 0 0
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Hepatitis C 0 0
Condition category
Condition code
Infection 0 0 0 0
Other infectious diseases
Oral and Gastrointestinal 0 0 0 0
Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

Study type
Description of intervention(s) / exposure
Treatment: Surgery - Campaign days

Experimental: Campaign Days - All participants have the intervention of the campaign days which include hepatitis C screening, fibroscans and clinical assessments.

Treatment: Surgery: Campaign days
Participants who consent will complete study procedures (Hep C test, fibroscan, questionnaire, clinical assessment) and followed up through medical record review.

Intervention code [1] 0 0
Treatment: Surgery
Comparator / control treatment
Control group

Primary outcome [1] 0 0
Number of participants commencing anti-HCV treatment - Evaluation of number of participants commencing anti-HCV treatment
Timepoint [1] 0 0
Every year post enrolment for up to 3 years

Key inclusion criteria
- Participant has voluntarily signed the informed consent form;

- 18 years of age or older;

- History of injecting drug use;

- Recent injecting drug use (previous six months) or currently receiving OST.
Minimum age
18 Years
Maximum age
No limit
Both males and females
Can healthy volunteers participate?
Key exclusion criteria
- Women who are, or might be pregnant.

Study design
Purpose of the study
Health Services Research
Allocation to intervention
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Masking / blinding
Open (masking not used)
Who is / are masked / blinded?

Intervention assignment
Single group
Other design features
Not Applicable
Type of endpoint(s)
Statistical methods / analysis

Recruitment status
Data analysis
Reason for early stopping/withdrawal
Other reasons
Date of first participant enrolment
Date of last participant enrolment
Date of last data collection
Sample size
Accrual to date
Recruitment in Australia
Recruitment state(s)
Recruitment hospital [1] 0 0
Coopers Cottage, Campbelltown Drug Health Services - Campbelltown
Recruitment hospital [2] 0 0
Rankin Court Treatment Centre - Darlinghurst
Recruitment hospital [3] 0 0
Liverpool Opioid Treatment Program - Liverpool
Recruitment hospital [4] 0 0
WSLHD Mount Druitt Drug Health OST Clinic - Mount Druitt
Recruitment hospital [5] 0 0
Lawrence Avenue Methadone Program (LAMP) - Nowra
Recruitment hospital [6] 0 0
The Orana Centre - Wollongong
Recruitment hospital [7] 0 0
Roma Street Clinic - Brisbane
Recruitment hospital [8] 0 0
Youthlink - Cairns
Recruitment postcode(s) [1] 0 0
2560 - Campbelltown
Recruitment postcode(s) [2] 0 0
2010 - Darlinghurst
Recruitment postcode(s) [3] 0 0
2170 - Liverpool
Recruitment postcode(s) [4] 0 0
2770 - Mount Druitt
Recruitment postcode(s) [5] 0 0
2541 - Nowra
Recruitment postcode(s) [6] 0 0
2500 - Wollongong
Recruitment postcode(s) [7] 0 0
4034 - Brisbane
Recruitment postcode(s) [8] 0 0
4870 - Cairns

Funding & Sponsors
Primary sponsor type
Kirby Institute
Other collaborator category [1] 0 0
Name [1] 0 0
National Health and Medical Research Council, Australia
Address [1] 0 0
Country [1] 0 0

Ethics approval
Ethics application status

Brief summary
The overall goals of the ETHOS II Project are to enhance hepatitis C virus (HCV) care in drug
treatment clinics and needle and syringe programs (NSPs) in New South Wales and Australia,
and to develop a translational framework for subsequent establishment of HCV screening and
treatment programs in drug treatment clinics and NSPs across NSW and nationally.
Trial website
Trial related presentations / publications
Public notes

Principal investigator
Name 0 0
Address 0 0
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for public queries
Name 0 0
David Silk, BSc
Address 0 0
Country 0 0
Phone 0 0
+61 2 9385 0878
Fax 0 0
Email 0 0
Contact person for scientific queries

Summary results
For IPD and results data, please see