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Trial registered on ANZCTR

Registration number
Ethics application status
Date submitted
Date registered
Date last updated
Date data sharing statement initially provided
Type of registration
Prospectively registered

Titles & IDs
Public title
Using behavioural economics to improve testing for HIV and other sexually transmitted infections among men who have sex with men
Scientific title
Using behavioural economics to improve testing for HIV and other sexually transmitted infections among men who have sex with men
Secondary ID [1] 300006 0
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Human immunodeficiency virus (HIV) 315491 0
sexually transmitted infection 315492 0
Condition category
Condition code
Infection 313778 313778 0 0
Acquired immune deficiency syndrome (AIDS / HIV)
Infection 313779 313779 0 0
Sexually transmitted infections

Study type
Description of intervention(s) / exposure
Reframing the content of SMS message to remind someone to get tested for HIV or other sexually transmitted infections (STIs).
Participants will receive a SMS message e.g. Positive frame: "To stay healthy, regular testing is recommended. Phone for an appointment"; Negative frame: "Not testing regularly might harm your health. Phone for an appointment"; Social norm frame: "The majority of people receiving this message will attend for STI. Phone for an appointment". This message will be administered according to the client's predetermined frequency of reminders (i.e. every 3 or 6 or 12 months). Melbourne Sexual Health Centre (MSHC) will send out the SMS. We will monitor whether clients are returning to MSHC within a month of receiving the message. If clients don't return to MSHC, they will receive a short SMS to see if they tested for STIs elsewhere.

The framing of the message will be changed every month - so all individuals scheduled to receive a reminder in that month will receive that framed message. We will run the trial over 6 months with rotating messages (e.g. month 1 = social norm, month 2 = positive framing, month 3 = negative framing, month 4 = social norm, month 5 = positive framing, month 6 = negative framing).
Intervention code [1] 316273 0
Early detection / Screening
Comparator / control treatment
Historical control group who have received traditional reminder SMS message (i.e. neutral frame: "Your next check-up is now due. Phone for an appointment") using Melbourne Sexual Health Centre records from Oct 2018 to October 2019.
Control group

Primary outcome [1] 322191 0
Testing for HIV/STI within one month of receiving the SMS message.
This will be through an audit of our clinic's medical record system to see if the person had re-attended for an STI test.
Timepoint [1] 322191 0
Within one month post-reminder.
Secondary outcome [1] 377633 0
HIV and/or STI positivity rate (composite outcome)
Audit of medical records
Timepoint [1] 377633 0
within 1 month of receiving SMS reminder
Secondary outcome [2] 377794 0
HIV positivity rate
Audit of medical records
Timepoint [2] 377794 0
within 1 month of receiving the SMS reminder
Secondary outcome [3] 377795 0
STI positivity rate (i.e. chlamydia or gonorrhoea or syphilis or mycoplasma genitalium or lymphogranuloma venereum or herpes)
Each STI will be evaluated separately.
Audit of medical records
Timepoint [3] 377795 0
within one month of SMS reminder

Key inclusion criteria
Men who have sex with men
age 18 years and over
Minimum age
18 Years
Maximum age
No limit
Can healthy volunteers participate?
Key exclusion criteria

Study design
Purpose of the study
Allocation to intervention
Non-randomised trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
not applicable
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
not applicable
Masking / blinding
Open (masking not used)
Who is / are masked / blinded?

Intervention assignment
Single group
Other design features
Not Applicable
Type of endpoint(s)
Statistical methods / analysis
Descriptive statistics to evaluate the proportion of men who were tested for STI/HIV following receipt of SMS message. Logistic regression models to identify factors associated with likelihood to test for STI/HIV e.g. age, educational level, location of residence, etc...

Recruitment status
Not yet recruiting
Date of first participant enrolment
Date of last participant enrolment
Date of last data collection
Sample size
Accrual to date
Recruitment in Australia
Recruitment state(s)

Funding & Sponsors
Funding source category [1] 304457 0
Name [1] 304457 0
Monash University
Address [1] 304457 0
Monash University, Wellington Rd, Clayton VIC 3800
Country [1] 304457 0
Primary sponsor type
Monash University
Monash University, Wellington Rd, Clayton VIC 3800
Secondary sponsor category [1] 304727 0
Name [1] 304727 0
Address [1] 304727 0
Country [1] 304727 0

Ethics approval
Ethics application status
Ethics committee name [1] 304892 0
Alfred Hospital Ethics Committee
Ethics committee address [1] 304892 0
55 Commercial Rd, Melbourne VIC 3004
Ethics committee country [1] 304892 0
Date submitted for ethics approval [1] 304892 0
Approval date [1] 304892 0
Ethics approval number [1] 304892 0

Brief summary
Regular HIV/sexually transmitted infection (STI) screening is particularly important for those at highest risk e.g. for men who have sex with men (MSM). Several national guidelines recommend sexually active individual to have an STI screening every 3 months. The aim of the proposed study will be to evaluate whether reframing SMS reminder messages may impact the retesting rates of clients of Melbourne Sexual Health Centre.
Trial website
Trial related presentations / publications
Public notes

Principal investigator
Name 98550 0
A/Prof Jason Ong
Address 98550 0
Melbourne Sexual Health Centre
580 Swanston Street, Carlton Victoria 3053
Country 98550 0
Phone 98550 0
+61 393416263
Fax 98550 0
Email 98550 0
Contact person for public queries
Name 98551 0
A/Prof Jason Ong
Address 98551 0
Melbourne Sexual Health Centre
580 Swanston Street, Carlton Victoria 3053
Country 98551 0
Phone 98551 0
+61 393416263
Fax 98551 0
Email 98551 0
Contact person for scientific queries
Name 98552 0
A/Prof Jason Ong
Address 98552 0
Melbourne Sexual Health Centre
580 Swanston Street, Carlton Victoria 3053
Country 98552 0
Phone 98552 0
+61 393416263
Fax 98552 0
Email 98552 0

Data sharing statement
Will individual participant data (IPD) for this trial be available (including data dictionaries)?
No/undecided IPD sharing reason/comment
We will provide aggregate/summary results to avoid identifying clients of our clinic.
What supporting documents are/will be available?
No other documents available
Summary results
No Results